儲(chǔ)存: -15°C to -25°C/1 year(Do not lower than -25°C)
克隆性: Monoclonal
克隆號(hào): PT1060R
特異性: Endogenous
基因名稱: NR4A1
蛋白名稱: Nuclear receptor subfamily 4 group A member 1
別名: NR4A1;GFRP1;HMR;NAK1;Nuclear receptor subfamily 4 group A member 1;Early response protein NAK1;Nuclear hormone receptor NUR/77;Nur77;Orphan nuclear receptor HMR;Orphan nuclear receptor TR3;ST-59;Testicular receptor 3
Organism-1: Human
基因ID-1: 3164
SwissProt-1: P22736
Organism-2: Mouse
基因ID-2: 15370
SwissProt-2: P12813
Organism-3: Rat
基因ID-3: 79240
SwissProt-3: P22829
背景: This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. Expression is induced by phytohemagglutinin in human lymphocytes and by serum stimulation of arrested fibroblasts. The encoded protein acts as a nuclear transcription factor. Translocation of the protein from the nucleus to mitochondria induces apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2011],
細(xì)胞定位: Nucleus . Cytoplasm . Mitochondrion . Nuclear export to the cytoplasm is XPO1-mediated and positively regulated by IFI27 (PubMed:22427340). Translocation to the mitochondrion upon interaction with RXRA and upon the presence of 9-cis retinoic acid (PubMed:17761950). .
儲(chǔ)存: -15°C to -25°C/1 year(Do not lower than -25°C)
克隆性: Monoclonal
克隆號(hào): PT1060R
特異性: Endogenous
基因名稱: NR4A1
蛋白名稱: Nuclear receptor subfamily 4 group A member 1
別名: NR4A1;GFRP1;HMR;NAK1;Nuclear receptor subfamily 4 group A member 1;Early response protein NAK1;Nuclear hormone receptor NUR/77;Nur77;Orphan nuclear receptor HMR;Orphan nuclear receptor TR3;ST-59;Testicular receptor 3
Organism-1: Human
基因ID-1: 3164
SwissProt-1: P22736
Organism-2: Mouse
基因ID-2: 15370
SwissProt-2: P12813
Organism-3: Rat
基因ID-3: 79240
SwissProt-3: P22829
背景: This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. Expression is induced by phytohemagglutinin in human lymphocytes and by serum stimulation of arrested fibroblasts. The encoded protein acts as a nuclear transcription factor. Translocation of the protein from the nucleus to mitochondria induces apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2011],
細(xì)胞定位: Nucleus . Cytoplasm . Mitochondrion . Nuclear export to the cytoplasm is XPO1-mediated and positively regulated by IFI27 (PubMed:22427340). Translocation to the mitochondrion upon interaction with RXRA and upon the presence of 9-cis retinoic acid (PubMed:17761950). .
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