儲(chǔ)存: -15°C to -25°C/1 year(Do not lower than -25°C)
克隆性: Monoclonal
克隆號(hào): PT0980R
特異性: Endogenous
基因名稱: MyD88
蛋白名稱: Myeloid differentiation primary response protein MyD88
別名: MYD88;Myeloid differentiation primary response protein MyD88
Organism-1: Human
基因ID-1: 4615
SwissProt-1: Q99836
Organism-2: Mouse
基因ID-2: 17874
SwissProt-2: P22366
Organism-3: Rat
基因ID-3: 301059
SwissProt-3: Q6Y1S1
背景: This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010],
儲(chǔ)存: -15°C to -25°C/1 year(Do not lower than -25°C)
克隆性: Monoclonal
克隆號(hào): PT0980R
特異性: Endogenous
基因名稱: MyD88
蛋白名稱: Myeloid differentiation primary response protein MyD88
別名: MYD88;Myeloid differentiation primary response protein MyD88
Organism-1: Human
基因ID-1: 4615
SwissProt-1: Q99836
Organism-2: Mouse
基因ID-2: 17874
SwissProt-2: P22366
Organism-3: Rat
基因ID-3: 301059
SwissProt-3: Q6Y1S1
背景: This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010],
細(xì)胞定位: Cytoplasm . Nucleus .
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