儲存: -15°C to -25°C/1 year(Do not lower than -25°C)
克隆號: PT0959R
特異性: Endogenous
基因名稱: FOXO4
蛋白名稱: Forkhead box protein O4
別名: FOXO4;AFX;AFX1;MLLT7;Forkhead box protein O4;Fork head domain transcription factor AFX1
Organism-1: Human
基因ID-1: 4303
SwissProt-1: P98177
Organism-2: Mouse
基因ID-2: 54601
SwissProt-2: Q9WVH3
背景: This gene encodes a member of the O class of winged helix/forkhead transcription factor family. Proteins encoded by this class are regulated by factors involved in growth and differentiation indicating they play a role in these processes. A translocation involving this gene on chromosome X and the homolog of the Drosophila trithorax gene, encoding a DNA binding protein, located on chromosome 11 is associated with leukemia. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2010],
細胞定位: Cytoplasm. Nucleus. When phosphorylated, translocated from nucleus to cytoplasm. Dephosphorylation triggers nuclear translocation. Monoubiquitination increases nuclear localization. When deubiquitinated, translocated from nucleus to cytoplasm.
儲存: -15°C to -25°C/1 year(Do not lower than -25°C)
克隆號: PT0959R
特異性: Endogenous
基因名稱: FOXO4
蛋白名稱: Forkhead box protein O4
別名: FOXO4;AFX;AFX1;MLLT7;Forkhead box protein O4;Fork head domain transcription factor AFX1
Organism-1: Human
基因ID-1: 4303
SwissProt-1: P98177
Organism-2: Mouse
基因ID-2: 54601
SwissProt-2: Q9WVH3
背景: This gene encodes a member of the O class of winged helix/forkhead transcription factor family. Proteins encoded by this class are regulated by factors involved in growth and differentiation indicating they play a role in these processes. A translocation involving this gene on chromosome X and the homolog of the Drosophila trithorax gene, encoding a DNA binding protein, located on chromosome 11 is associated with leukemia. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2010],
細胞定位: Cytoplasm. Nucleus. When phosphorylated, translocated from nucleus to cytoplasm. Dephosphorylation triggers nuclear translocation. Monoubiquitination increases nuclear localization. When deubiquitinated, translocated from nucleus to cytoplasm.
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