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PMS2 Rabbit mAb

商品貨號(hào)： PRM8627

適應(yīng) 性： 人,

￥7000元

規(guī)格：

500ul

在線咨詢

MSDS

說明書

商品描述

發(fā)貨日期：現(xiàn)貨
靶點(diǎn)-Target： PMS2
反應(yīng)性-Reactivity：人,
應(yīng)用-Applications： WB,IHC,IF,IP,ELISA
MW(Calculated)： 96kD
MW(Observed)： 110kD
宿主物種-Host Species： Rabbit
同種型-Isotype： IgG,Kappa
偶聯(lián)-Conjugate： Unmodified
推薦稀釋比： IHC 1:200-1000;WB 1:500-5000;IF 1:200-1000;ELISA 1:5000-20000;IP 1:50-200
組成： PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
純化工藝： Protein A
儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
克隆性： Monoclonal
克隆號(hào)： PT0045R
特異性： Endogenous
基因名稱： PMS2 PMSL2
蛋白名稱： Postmeiotic Segregation Increased 2(PMS2)
別名： Mismatch repair endonuclease PMS2;DNA mismatch repair protein PMS2;PMS1 protein homolog 2;
Organism-1： Human
基因ID-1： 5395
SwissProt-1： P54278
背景： The protein encoded by this gene is a key component of the mismatch repair system that functions to correct DNA mismatches and small insertions and deletions that can occur during DNA replication and homologous recombination. This protein forms heterodimers with the gene product of the mutL homolog 1 (MLH1) gene to form the MutL-alpha heterodimer. The MutL-alpha heterodimer possesses an endonucleolytic activity that is activated following recognition of mismatches and insertion/deletion loops by the MutS-alpha and MutS-beta heterodimers, and is necessary for removal of the mismatched DNA. There is a DQHA(X)2E(X)4E motif found at the C-terminus of the protein encoded by this gene that forms part of the active site of the nuclease. Mutations in this gene have been associated with hereditary nonpolyposis colorectal cancer (HNPCC; also known as Lynch syndrome) and Turcot syndrome
細(xì)胞定位： Nuclear

PMS2 Rabbit mAb

Catalog No PRM8627

Product information

發(fā)貨日期：現(xiàn)貨
靶點(diǎn)-Target： PMS2
反應(yīng)性-Reactivity：人,
應(yīng)用-Applications： WB,IHC,IF,IP,ELISA
MW(Calculated)： 96kD
MW(Observed)： 110kD
宿主物種-Host Species： Rabbit
同種型-Isotype： IgG,Kappa
偶聯(lián)-Conjugate： Unmodified
推薦稀釋比： IHC 1:200-1000;WB 1:500-5000;IF 1:200-1000;ELISA 1:5000-20000;IP 1:50-200
組成： PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
純化工藝： Protein A
儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
克隆性： Monoclonal
克隆號(hào)： PT0045R
特異性： Endogenous
基因名稱： PMS2 PMSL2
蛋白名稱： Postmeiotic Segregation Increased 2(PMS2)
別名： Mismatch repair endonuclease PMS2;DNA mismatch repair protein PMS2;PMS1 protein homolog 2;
Organism-1： Human
基因ID-1： 5395
SwissProt-1： P54278
背景： The protein encoded by this gene is a key component of the mismatch repair system that functions to correct DNA mismatches and small insertions and deletions that can occur during DNA replication and homologous recombination. This protein forms heterodimers with the gene product of the mutL homolog 1 (MLH1) gene to form the MutL-alpha heterodimer. The MutL-alpha heterodimer possesses an endonucleolytic activity that is activated following recognition of mismatches and insertion/deletion loops by the MutS-alpha and MutS-beta heterodimers, and is necessary for removal of the mismatched DNA. There is a DQHA(X)2E(X)4E motif found at the C-terminus of the protein encoded by this gene that forms part of the active site of the nuclease. Mutations in this gene have been associated with hereditary nonpolyposis colorectal cancer (HNPCC; also known as Lynch syndrome) and Turcot syndrome
細(xì)胞定位： Nuclear

Hunan UPT Biotechnology Co.,Ltd

Website：m.tjdqdt.com Servive hotline :4006916686

E-mail：service@uptbio.com

Address：

Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.

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