儲存: -15°C to -25°C/1 year(Do not lower than -25°C)
克隆性: Monoclonal
克隆號: PT0385R
特異性: Endogenous
基因名稱: MT-CO2 COII COXII MTCO2
蛋白名稱: Cytochrome c oxidase subunit 2 (Cytochrome c oxidase polypeptide II)
Organism-1: Human
基因ID-1: 4513
SwissProt-1: P00403
Organism-2: Mouse
SwissProt-2: P00405
Organism-3: Rat
SwissProt-3: P00406
背景: cofactor:Copper A.,disease:Defects in MT-CO2 are a cause of cytochrome c oxidase deficiency (COX deficiency) [MIM:220110]; also called mitochondrial complex IV deficiency. COX deficiency is a clinically heterogeneous disorder. The clinical features are ranging from isolated myopathy to severe multisystem disease, with onset from infancy to adulthood.,disease:Defects in MT-CO2 are associated with tumor formation.,function:Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. Subunit 2 transfers the electrons from cytochrome c via its binuclear copper A center to the bimetallic center of the catalytic subunit 1.,similarity:Belongs to the cytochrome c oxidase subunit 2 family.,
儲存: -15°C to -25°C/1 year(Do not lower than -25°C)
克隆性: Monoclonal
克隆號: PT0385R
特異性: Endogenous
基因名稱: MT-CO2 COII COXII MTCO2
蛋白名稱: Cytochrome c oxidase subunit 2 (Cytochrome c oxidase polypeptide II)
Organism-1: Human
基因ID-1: 4513
SwissProt-1: P00403
Organism-2: Mouse
SwissProt-2: P00405
Organism-3: Rat
SwissProt-3: P00406
背景: cofactor:Copper A.,disease:Defects in MT-CO2 are a cause of cytochrome c oxidase deficiency (COX deficiency) [MIM:220110]; also called mitochondrial complex IV deficiency. COX deficiency is a clinically heterogeneous disorder. The clinical features are ranging from isolated myopathy to severe multisystem disease, with onset from infancy to adulthood.,disease:Defects in MT-CO2 are associated with tumor formation.,function:Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. Subunit 2 transfers the electrons from cytochrome c via its binuclear copper A center to the bimetallic center of the catalytic subunit 1.,similarity:Belongs to the cytochrome c oxidase subunit 2 family.,
細胞定位: Cytoplasmic
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