儲存: -15°C to -25°C/1 year(Do not lower than -25°C)
克隆性: Monoclonal
克隆號: PT0079R
特異性: Endogenous
基因名稱: STAT1
蛋白名稱: Signal transducer and activator of transcription 1-alpha/beta (Transcription factor ISGF-3 components p91/p84)
別名: Signal transducer and activator of transcription 1-alpha/beta;Transcription factor ISGF-3 components p91/p84;
Organism-1: Human
基因ID-1: 6772
SwissProt-1: P42224
Organism-2: Mouse
SwissProt-2: P42225
背景: signal transducer and activator of transcription 1(STAT1) Homo sapiens The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. Two alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008],
儲存: -15°C to -25°C/1 year(Do not lower than -25°C)
克隆性: Monoclonal
克隆號: PT0079R
特異性: Endogenous
基因名稱: STAT1
蛋白名稱: Signal transducer and activator of transcription 1-alpha/beta (Transcription factor ISGF-3 components p91/p84)
別名: Signal transducer and activator of transcription 1-alpha/beta;Transcription factor ISGF-3 components p91/p84;
Organism-1: Human
基因ID-1: 6772
SwissProt-1: P42224
Organism-2: Mouse
SwissProt-2: P42225
背景: signal transducer and activator of transcription 1(STAT1) Homo sapiens The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. Two alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008],
細(xì)胞定位: Nuclear
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