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PERK Rabbit mAb

商品貨號(hào)： PRM8510

適應(yīng) 性： 人,小鼠,大鼠

￥800元

規(guī)格：

50ul

在線咨詢(xún)

MSDS

說(shuō)明書(shū)

商品描述

發(fā)貨日期：現(xiàn)貨
靶點(diǎn)-Target： PERK
反應(yīng)性-Reactivity：人,小鼠,大鼠
應(yīng)用-Applications： WB,IF,IP,ELISA
MW(Calculated)： 125kD
MW(Observed)： 140kD
宿主物種-Host Species： Rabbit
同種型-Isotype： IgG,Kappa
偶聯(lián)-Conjugate： Unmodified
推薦稀釋比： WB 1:1000-1:5000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200,
組成： PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
純化工藝： Protein A
儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
克隆性： Monoclonal
克隆號(hào)： PT0310R
特異性： Endogenous
基因名稱(chēng)： >>Mitophagy - animal;>>Autophagy - animal;>>Protein processing in endoplasmic reticulum;>>Apoptosis;>>Non-alcoholic fatty liver disease;>>Alzheimer disease;>>Parkinson disease;>>Amyotrophic lateral sclerosis;>>Prion disease;>>Pathways of neurodegeneration - multiple diseases;>>Hepatitis C;>>Measles;>>Herpes simplex virus 1 infection;>>Lipid and atherosclerosis
蛋白名稱(chēng)： EIF2AK3
別名： EIF2AK3;PEK;PERK;Eukaryotic translation initiation factor 2-alpha kinase 3;PRKR-like endoplasmic reticulum kinase;Pancreatic eIF2-alpha kinase;HsPEK
Organism-1： Human
基因ID-1： 9451
SwissProt-1： Q9NZJ5
Organism-2： Mouse
SwissProt-2： Q9Z2B5
Organism-3： Rat
基因ID-3： 29702
SwissProt-3： Q9Z1Z1
背景： The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2, leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. This protein is thought to modulate mitochondrial function. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. Mutations in this gene are associated with Wolcott-Rallison syndrome. [provided by RefSeq, Sep 2015],
細(xì)胞定位： Endoplasmic reticulum membrane

PERK Rabbit mAb

Catalog No PRM8510

Product information

發(fā)貨日期：現(xiàn)貨
靶點(diǎn)-Target： PERK
反應(yīng)性-Reactivity：人,小鼠,大鼠
應(yīng)用-Applications： WB,IF,IP,ELISA
MW(Calculated)： 125kD
MW(Observed)： 140kD
宿主物種-Host Species： Rabbit
同種型-Isotype： IgG,Kappa
偶聯(lián)-Conjugate： Unmodified
推薦稀釋比： WB 1:1000-1:5000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200,
組成： PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
純化工藝： Protein A
儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
克隆性： Monoclonal
克隆號(hào)： PT0310R
特異性： Endogenous
基因名稱(chēng)： >>Mitophagy - animal;>>Autophagy - animal;>>Protein processing in endoplasmic reticulum;>>Apoptosis;>>Non-alcoholic fatty liver disease;>>Alzheimer disease;>>Parkinson disease;>>Amyotrophic lateral sclerosis;>>Prion disease;>>Pathways of neurodegeneration - multiple diseases;>>Hepatitis C;>>Measles;>>Herpes simplex virus 1 infection;>>Lipid and atherosclerosis
蛋白名稱(chēng)： EIF2AK3
別名： EIF2AK3;PEK;PERK;Eukaryotic translation initiation factor 2-alpha kinase 3;PRKR-like endoplasmic reticulum kinase;Pancreatic eIF2-alpha kinase;HsPEK
Organism-1： Human
基因ID-1： 9451
SwissProt-1： Q9NZJ5
Organism-2： Mouse
SwissProt-2： Q9Z2B5
Organism-3： Rat
基因ID-3： 29702
SwissProt-3： Q9Z1Z1
背景： The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2, leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. This protein is thought to modulate mitochondrial function. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. Mutations in this gene are associated with Wolcott-Rallison syndrome. [provided by RefSeq, Sep 2015],
細(xì)胞定位： Endoplasmic reticulum membrane

Hunan UPT Biotechnology Co.,Ltd

Website：m.tjdqdt.com Servive hotline :4006916686

E-mail：service@uptbio.com

Address：

Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.

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