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ROCK1 Rabbit mAb

商品貨號(hào)： PRM8506

適應(yīng) 性： 人,小鼠,大鼠

￥800元

規(guī)格：

50ul

在線咨詢

MSDS

說(shuō)明書(shū)

商品描述

發(fā)貨日期：現(xiàn)貨
靶點(diǎn)-Target： ROCK1
反應(yīng)性-Reactivity：人,小鼠,大鼠
應(yīng)用-Applications： WB,IHC,IF,IP,ELISA
MW(Calculated)： 158kD
MW(Observed)： 158kD
宿主物種-Host Species： Rabbit
同種型-Isotype： IgG,Kappa
偶聯(lián)-Conjugate： Unmodified
推薦稀釋比： IHC 1:200-1:1000;WB 1:1000-1:5000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200,
組成： PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
純化工藝： Protein A
儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
克隆性： Monoclonal
克隆號(hào)： PT0305R
特異性： Endogenous
基因名稱： >>cGMP-PKG signaling pathway;>>cAMP signaling pathway;>>Chemokine signaling pathway;>>Sphingolipid signaling pathway;>>Vascular smooth muscle contraction;>>TGF-beta signaling pathway;>>Axon guidance;>>Focal adhesion;>>Tight junction;>>Platelet activation;>>Leukocyte transendothelial migration;>>Regulation of actin cytoskeleton;>>Oxytocin signaling pathway;>>Pathogenic Escherichia coli infection;>>Shigellosis;>>Yersinia infection;>>Human cytomegalovirus infection;>>Pathways in cancer;>>Proteoglycans in cancer;>>MicroRNAs in cancer
蛋白名稱： ROCK1
別名： ROCK1;Rho-associated protein kinase 1;Renal carcinoma antigen NY-REN-35;Rho-associated;coiled-coil-containing protein kinase 1;Rho-associated, coiled-coil-containing protein kinase I;ROCK-I;p160 ROCK-1;p160ROCK
Organism-1： Human
基因ID-1： 6093
SwissProt-1： Q13464
Organism-2： Mouse
基因ID-2： 19877
SwissProt-2： P70335
Organism-3： Rat
基因ID-3： 81762
SwissProt-3： Q63644
背景： This gene encodes a protein serine/threonine kinase that is activated when bound to the GTP-bound form of Rho. The small GTPase Rho regulates formation of focal adhesions and stress fibers of fibroblasts, as well as adhesion and aggregation of platelets and lymphocytes by shuttling between the inactive GDP-bound form and the active GTP-bound form. Rho is also essential in cytokinesis and plays a role in transcriptional activation by serum response factor. This protein, a downstream effector of Rho, phosphorylates and activates LIM kinase, which in turn, phosphorylates cofilin, inhibiting its actin-depolymerizing activity. A pseudogene, related to this gene, is also located on chromosome 18. [provided by RefSeq, Aug 2015],
細(xì)胞定位： Cytoplasm, Membrane

ROCK1 Rabbit mAb

Catalog No PRM8506

Product information

發(fā)貨日期：現(xiàn)貨
靶點(diǎn)-Target： ROCK1
反應(yīng)性-Reactivity：人,小鼠,大鼠
應(yīng)用-Applications： WB,IHC,IF,IP,ELISA
MW(Calculated)： 158kD
MW(Observed)： 158kD
宿主物種-Host Species： Rabbit
同種型-Isotype： IgG,Kappa
偶聯(lián)-Conjugate： Unmodified
推薦稀釋比： IHC 1:200-1:1000;WB 1:1000-1:5000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200,
組成： PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
純化工藝： Protein A
儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
克隆性： Monoclonal
克隆號(hào)： PT0305R
特異性： Endogenous
基因名稱： >>cGMP-PKG signaling pathway;>>cAMP signaling pathway;>>Chemokine signaling pathway;>>Sphingolipid signaling pathway;>>Vascular smooth muscle contraction;>>TGF-beta signaling pathway;>>Axon guidance;>>Focal adhesion;>>Tight junction;>>Platelet activation;>>Leukocyte transendothelial migration;>>Regulation of actin cytoskeleton;>>Oxytocin signaling pathway;>>Pathogenic Escherichia coli infection;>>Shigellosis;>>Yersinia infection;>>Human cytomegalovirus infection;>>Pathways in cancer;>>Proteoglycans in cancer;>>MicroRNAs in cancer
蛋白名稱： ROCK1
別名： ROCK1;Rho-associated protein kinase 1;Renal carcinoma antigen NY-REN-35;Rho-associated;coiled-coil-containing protein kinase 1;Rho-associated, coiled-coil-containing protein kinase I;ROCK-I;p160 ROCK-1;p160ROCK
Organism-1： Human
基因ID-1： 6093
SwissProt-1： Q13464
Organism-2： Mouse
基因ID-2： 19877
SwissProt-2： P70335
Organism-3： Rat
基因ID-3： 81762
SwissProt-3： Q63644
背景： This gene encodes a protein serine/threonine kinase that is activated when bound to the GTP-bound form of Rho. The small GTPase Rho regulates formation of focal adhesions and stress fibers of fibroblasts, as well as adhesion and aggregation of platelets and lymphocytes by shuttling between the inactive GDP-bound form and the active GTP-bound form. Rho is also essential in cytokinesis and plays a role in transcriptional activation by serum response factor. This protein, a downstream effector of Rho, phosphorylates and activates LIM kinase, which in turn, phosphorylates cofilin, inhibiting its actin-depolymerizing activity. A pseudogene, related to this gene, is also located on chromosome 18. [provided by RefSeq, Aug 2015],
細(xì)胞定位： Cytoplasm, Membrane

Hunan UPT Biotechnology Co.,Ltd

Website：m.tjdqdt.com Servive hotline :4006916686

E-mail：service@uptbio.com

Address：

Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.

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