儲(chǔ)存: -15°C to -25°C/1 year(Do not lower than -25°C)
克隆性: Monoclonal
克隆號(hào): PT0250R
特異性: Endogenous
基因名稱: SIRT3
蛋白名稱: NAD-dependent protein deacetylase sirtuin-3 mitochondrial
別名: SIRT3;SIR2L3;NAD-dependent protein deacetylase sirtuin-3;mitochondrial;hSIRT3;Regulatory protein SIR2 homolog 3;SIR2-like protein 3
Organism-1: Human
基因ID-1: 23410
SwissProt-1: Q9NTG7
Organism-2: Mouse
SwissProt-2: Q8R104
背景: This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Two alternatively spliced transcript variants that encode different proteins have been described for this gene. [provided by RefSeq, Jul 2008],
儲(chǔ)存: -15°C to -25°C/1 year(Do not lower than -25°C)
克隆性: Monoclonal
克隆號(hào): PT0250R
特異性: Endogenous
基因名稱: SIRT3
蛋白名稱: NAD-dependent protein deacetylase sirtuin-3 mitochondrial
別名: SIRT3;SIR2L3;NAD-dependent protein deacetylase sirtuin-3;mitochondrial;hSIRT3;Regulatory protein SIR2 homolog 3;SIR2-like protein 3
Organism-1: Human
基因ID-1: 23410
SwissProt-1: Q9NTG7
Organism-2: Mouse
SwissProt-2: Q8R104
背景: This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Two alternatively spliced transcript variants that encode different proteins have been described for this gene. [provided by RefSeq, Jul 2008],
細(xì)胞定位: Mitochondrion matrix
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