儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
克隆性： Monoclonal
克隆號： PT0241R
特異性： Endogenous
基因名稱： NRAS HRAS1
蛋白名稱： GTPase NRas (Transforming protein N-Ras)
Organism-1： Human
基因ID-1： 4893
SwissProt-1： P01111
Organism-2： Mouse
SwissProt-2： P08556
Organism-3： Rat
SwissProt-3： Q04970
背景： This is an N-ras oncogene encoding a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. The encoded protein, which has intrinsic GTPase activity, is activated by a guanine nucleotide-exchange factor and inactivated by a GTPase activating protein. Mutations in this gene have been associated with somatic rectal cancer, follicular thyroid cancer, autoimmune lymphoproliferative syndrome, Noonan syndrome, and juvenile myelomonocytic leukemia. [provided by RefSeq, Jun 2011]
儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
克隆性： Monoclonal
克隆號： PT0241R
特異性： Endogenous
基因名稱： NRAS HRAS1
蛋白名稱： GTPase NRas (Transforming protein N-Ras)
Organism-1： Human
基因ID-1： 4893
SwissProt-1： P01111
Organism-2： Mouse
SwissProt-2： P08556
Organism-3： Rat
SwissProt-3： Q04970
背景： This is an N-ras oncogene encoding a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. The encoded protein, which has intrinsic GTPase activity, is activated by a guanine nucleotide-exchange factor and inactivated by a GTPase activating protein. Mutations in this gene have been associated with somatic rectal cancer, follicular thyroid cancer, autoimmune lymphoproliferative syndrome, Noonan syndrome, and juvenile myelomonocytic leukemia. [provided by RefSeq, Jun 2011]
細胞定位： Membrane
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