儲(chǔ)存: -15°C to -25°C/1 year(Do not lower than -25°C)
克隆性: Monoclonal
克隆號(hào): PT0126R
特異性: Endogenous
基因名稱: TARDBP TDP43
蛋白名稱: TAR DNA-binding protein 43 (TDP-43)
Organism-1: Human
基因ID-1: 23435
SwissProt-1: Q13148
Organism-2: Mouse
SwissProt-2: Q921F2
背景: TAR DNA binding protein(TARDBP) Homo sapiens HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20. [provided by RefSeq, Jul 2008],
儲(chǔ)存: -15°C to -25°C/1 year(Do not lower than -25°C)
克隆性: Monoclonal
克隆號(hào): PT0126R
特異性: Endogenous
基因名稱: TARDBP TDP43
蛋白名稱: TAR DNA-binding protein 43 (TDP-43)
Organism-1: Human
基因ID-1: 23435
SwissProt-1: Q13148
Organism-2: Mouse
SwissProt-2: Q921F2
背景: TAR DNA binding protein(TARDBP) Homo sapiens HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20. [provided by RefSeq, Jul 2008],
細(xì)胞定位: Nucleus
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