別名: FTO;KIAA1752;Alpha-ketoglutarate-dependent dioxygenase FTO;Fat mass and obesity-associated protein
Organism-1: Human
基因ID-1: 79068
SwissProt-1: Q9C0B1
Organism-2: Mouse
基因ID-2: 26383
SwissProt-2: Q8BGW1
Organism-3: Rat
基因ID-3: 291905
SwissProt-3: Q2A121
背景: This gene is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non-heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes. [provided by RefSeq, Jul 2011],
別名: FTO;KIAA1752;Alpha-ketoglutarate-dependent dioxygenase FTO;Fat mass and obesity-associated protein
Organism-1: Human
基因ID-1: 79068
SwissProt-1: Q9C0B1
Organism-2: Mouse
基因ID-2: 26383
SwissProt-2: Q8BGW1
Organism-3: Rat
基因ID-3: 291905
SwissProt-3: Q2A121
背景: This gene is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non-heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes. [provided by RefSeq, Jul 2011],
細胞定位: Cytoplasm, Nucleus
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