儲存: -15°C to -25°C/1 year(Do not lower than -25°C)
克隆性: Monoclonal
克隆號: PT0549R
特異性: Endogenous
基因名稱: EIF4EBP1
蛋白名稱: Eukaryotic translation initiation factor 4E-binding protein 1
別名: EIF4EBP1;Eukaryotic translation initiation factor 4E-binding protein 1;4E-BP1;eIF4E-binding protein 1;Phosphorylated heat- and acid-stable protein regulated by insulin 1;PHAS-I
Organism-1: Human
基因ID-1: 1978
SwissProt-1: Q13541
Organism-2: Mouse
基因ID-2: 13685
SwissProt-2: Q60876
Organism-3: Rat
基因ID-3: 116636
SwissProt-3: Q62622
背景: This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation. [provided by RefSeq, Jul 2008],
儲存: -15°C to -25°C/1 year(Do not lower than -25°C)
克隆性: Monoclonal
克隆號: PT0549R
特異性: Endogenous
基因名稱: EIF4EBP1
蛋白名稱: Eukaryotic translation initiation factor 4E-binding protein 1
別名: EIF4EBP1;Eukaryotic translation initiation factor 4E-binding protein 1;4E-BP1;eIF4E-binding protein 1;Phosphorylated heat- and acid-stable protein regulated by insulin 1;PHAS-I
Organism-1: Human
基因ID-1: 1978
SwissProt-1: Q13541
Organism-2: Mouse
基因ID-2: 13685
SwissProt-2: Q60876
Organism-3: Rat
基因ID-3: 116636
SwissProt-3: Q62622
背景: This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation. [provided by RefSeq, Jul 2008],
細胞定位: Nucleus
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