儲存: -15°C to -25°C/1 year(Do not lower than -25°C)
克隆性: Monoclonal
克隆號: PT0607R
特異性: Endogenous
基因名稱: BBC3
蛋白名稱: Bcl-2-binding component 3
別名: BBC3;PUMA;Bcl-2-binding component 3;JFY-1;p53 up-regulated modulator of apoptosis
Organism-1: Human
基因ID-1: 27113
SwissProt-1: Q9BXH1
Organism-2: Mouse
基因ID-2: 170770
SwissProt-2: Q99ML1
Organism-3: Rat
基因ID-3: 317673
SwissProt-3: Q80ZG6
背景: This gene encodes a member of the BCL-2 family of proteins. This family member belongs to the BH3-only pro-apoptotic subclass. The protein cooperates with direct activator proteins to induce mitochondrial outer membrane permeabilization and apoptosis. It can bind to anti-apoptotic Bcl-2 family members to induce mitochondrial dysfunction and caspase activation. Because of its pro-apoptotic role, this gene is a potential drug target for cancer therapy and for tissue injury. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2011],
儲存: -15°C to -25°C/1 year(Do not lower than -25°C)
克隆性: Monoclonal
克隆號: PT0607R
特異性: Endogenous
基因名稱: BBC3
蛋白名稱: Bcl-2-binding component 3
別名: BBC3;PUMA;Bcl-2-binding component 3;JFY-1;p53 up-regulated modulator of apoptosis
Organism-1: Human
基因ID-1: 27113
SwissProt-1: Q9BXH1
Organism-2: Mouse
基因ID-2: 170770
SwissProt-2: Q99ML1
Organism-3: Rat
基因ID-3: 317673
SwissProt-3: Q80ZG6
背景: This gene encodes a member of the BCL-2 family of proteins. This family member belongs to the BH3-only pro-apoptotic subclass. The protein cooperates with direct activator proteins to induce mitochondrial outer membrane permeabilization and apoptosis. It can bind to anti-apoptotic Bcl-2 family members to induce mitochondrial dysfunction and caspase activation. Because of its pro-apoptotic role, this gene is a potential drug target for cancer therapy and for tissue injury. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2011],
細(xì)胞定位: Mitochondrion
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