儲存: -15°C to -25°C/1 year(Do not lower than -25°C)
克隆性: Monoclonal
克隆號: PT0600R
特異性: Endogenous
基因名稱: HDAC4
蛋白名稱: Histone deacetylase 4
別名: HDAC4;KIAA0288;Histone deacetylase 4;HD4
Organism-1: Human
基因ID-1: 9759
SwissProt-1: P56524
Organism-2: Mouse
基因ID-2: 208727
SwissProt-2: Q6NZM9
Organism-3: Rat
基因ID-3: 363287
SwissProt-3: Q99P99
背景: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3. [provided by RefSeq, Jul 2008],
儲存: -15°C to -25°C/1 year(Do not lower than -25°C)
克隆性: Monoclonal
克隆號: PT0600R
特異性: Endogenous
基因名稱: HDAC4
蛋白名稱: Histone deacetylase 4
別名: HDAC4;KIAA0288;Histone deacetylase 4;HD4
Organism-1: Human
基因ID-1: 9759
SwissProt-1: P56524
Organism-2: Mouse
基因ID-2: 208727
SwissProt-2: Q6NZM9
Organism-3: Rat
基因ID-3: 363287
SwissProt-3: Q99P99
背景: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3. [provided by RefSeq, Jul 2008],
細胞定位: Cytoplasm, Nucleus
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