儲(chǔ)存: -15°C to -25°C/1 year(Do not lower than -25°C)
克隆性: Monoclonal
克隆號(hào): PT0592R
特異性: Endogenous
基因名稱: PTPN11
蛋白名稱: Tyrosine-protein phosphatase non-receptor type 11
別名: PTPN11;PTP2C;SHPTP2;Tyrosine-protein phosphatase non-receptor type 11;Protein-tyrosine phosphatase 1D;PTP-1D;Protein-tyrosine phosphatase 2C;PTP-2C;SH-PTP2;SHP-2;Shp2;SH-PTP3
Organism-1: Human
基因ID-1: 5781
SwissProt-1: Q06124
Organism-2: Mouse
基因ID-2: 19247
SwissProt-2: P35235
Organism-3: Rat
基因ID-3: 25622
SwissProt-3: P41499
背景: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in this gene are a cause of Noonan syndrome as well as acute myeloid leukemia. [provided by RefSeq, Aug 2016],
儲(chǔ)存: -15°C to -25°C/1 year(Do not lower than -25°C)
克隆性: Monoclonal
克隆號(hào): PT0592R
特異性: Endogenous
基因名稱: PTPN11
蛋白名稱: Tyrosine-protein phosphatase non-receptor type 11
別名: PTPN11;PTP2C;SHPTP2;Tyrosine-protein phosphatase non-receptor type 11;Protein-tyrosine phosphatase 1D;PTP-1D;Protein-tyrosine phosphatase 2C;PTP-2C;SH-PTP2;SHP-2;Shp2;SH-PTP3
Organism-1: Human
基因ID-1: 5781
SwissProt-1: Q06124
Organism-2: Mouse
基因ID-2: 19247
SwissProt-2: P35235
Organism-3: Rat
基因ID-3: 25622
SwissProt-3: P41499
背景: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in this gene are a cause of Noonan syndrome as well as acute myeloid leukemia. [provided by RefSeq, Aug 2016],
細(xì)胞定位: Cytoplasm, Nucleus
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