儲(chǔ)存: -15°C to -25°C/1 year(Do not lower than -25°C)
克隆性: Monoclonal
克隆號(hào): PT0642R
特異性: Endogenous
基因名稱: MMP2
蛋白名稱: 72 kDa type IV collagenase
別名: MMP2;CLG4A;72 kDa type IV collagenase;72 kDa gelatinase;Gelatinase A;Matrix metalloproteinase-2;MMP-2;TBE-1
Organism-1: Human
基因ID-1: 4313
SwissProt-1: P08253
Organism-2: Mouse
基因ID-2: 17390
SwissProt-2: P33434
Organism-3: Rat
基因ID-3: 81686
SwissProt-3: P33436
背景: matrix metallopeptidase 2(MMP2) Homo sapiens This gene is a member of the matrix metalloproteinase (MMP) gene family, that are zinc-dependent enzymes capable of cleaving components of the extracellular matrix and molecules involved in signal transduction. The protein encoded by this gene is a gelatinase A, type IV collagenase, that contains three fibronectin type II repeats in its catalytic site that allow binding of denatured type IV and V collagen and elastin. Unlike most MMP family members, activation of this protein can occur on the cell membrane. This enzyme can be activated extracellularly by proteases, or, intracellulary by its S-glutathiolation with no requirement for proteolytical removal of the pro-domain. This protein is thought to be involved in multiple pathways including roles in the nervous system, endometrial menstrual breakdown, regulation of vascularization, and metastasis. Mutations in this gene have been associated with Win
儲(chǔ)存: -15°C to -25°C/1 year(Do not lower than -25°C)
克隆性: Monoclonal
克隆號(hào): PT0642R
特異性: Endogenous
基因名稱: MMP2
蛋白名稱: 72 kDa type IV collagenase
別名: MMP2;CLG4A;72 kDa type IV collagenase;72 kDa gelatinase;Gelatinase A;Matrix metalloproteinase-2;MMP-2;TBE-1
Organism-1: Human
基因ID-1: 4313
SwissProt-1: P08253
Organism-2: Mouse
基因ID-2: 17390
SwissProt-2: P33434
Organism-3: Rat
基因ID-3: 81686
SwissProt-3: P33436
背景: matrix metallopeptidase 2(MMP2) Homo sapiens This gene is a member of the matrix metalloproteinase (MMP) gene family, that are zinc-dependent enzymes capable of cleaving components of the extracellular matrix and molecules involved in signal transduction. The protein encoded by this gene is a gelatinase A, type IV collagenase, that contains three fibronectin type II repeats in its catalytic site that allow binding of denatured type IV and V collagen and elastin. Unlike most MMP family members, activation of this protein can occur on the cell membrane. This enzyme can be activated extracellularly by proteases, or, intracellulary by its S-glutathiolation with no requirement for proteolytical removal of the pro-domain. This protein is thought to be involved in multiple pathways including roles in the nervous system, endometrial menstrual breakdown, regulation of vascularization, and metastasis. Mutations in this gene have been associated with Win
細(xì)胞定位: Cytoplasm, Nucleus
Hunan UPT Biotechnology Co.,Ltd
Website:m.tjdqdt.com Servive hotline :4006916686
E-mail:service@uptbio.com
Address:
Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road,
Yuelu District, Changsha City, Hunan Province, China.