儲存: -15°C to -25°C/1 year(Do not lower than -25°C)
克隆性: Monoclonal
克隆號: PT0689R
特異性: Endogenous
基因名稱: IL1B IL1F2
蛋白名稱: Interleukin-1 beta (IL-1 beta) (Catabolin)
別名: Interleukin-1 beta;IL-1 beta;Catabolin;
Organism-1: Human
基因ID-1: 3553
SwissProt-1: P01584
Organism-2: Mouse
基因ID-2: 16176
SwissProt-2: P10749
Organism-3: Rat
SwissProt-3: Q63264
背景: interleukin 1 beta(IL1B) Homo sapiens The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. [provided by RefSeq, Jul 2008],
儲存: -15°C to -25°C/1 year(Do not lower than -25°C)
克隆性: Monoclonal
克隆號: PT0689R
特異性: Endogenous
基因名稱: IL1B IL1F2
蛋白名稱: Interleukin-1 beta (IL-1 beta) (Catabolin)
別名: Interleukin-1 beta;IL-1 beta;Catabolin;
Organism-1: Human
基因ID-1: 3553
SwissProt-1: P01584
Organism-2: Mouse
基因ID-2: 16176
SwissProt-2: P10749
Organism-3: Rat
SwissProt-3: Q63264
背景: interleukin 1 beta(IL1B) Homo sapiens The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. [provided by RefSeq, Jul 2008],
細胞定位: Secreted
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