儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
克隆性： Monoclonal
克隆號： PT0114R
特異性： Endogenous
基因名稱： STAT2
蛋白名稱： Signal transducer and activator of transcription 2
別名： STAT2;Signal transducer and activator of transcription 2;p113
Organism-1： Human
基因ID-1： 6773
SwissProt-1： P52630
Organism-2： Mouse
SwissProt-2： Q9WVL2
背景： The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. In response to interferon (IFN), this protein forms a complex with STAT1 and IFN regulatory factor family protein p48 (ISGF3G), in which this protein acts as a transactivator, but lacks the ability to bind DNA directly. Transcription adaptor P300/CBP (EP300/CREBBP) has been shown to interact specifically with this protein, which is thought to be involved in the process of blocking IFN-alpha response by adenovirus. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010],
儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
克隆性： Monoclonal
克隆號： PT0114R
特異性： Endogenous
基因名稱： STAT2
蛋白名稱： Signal transducer and activator of transcription 2
別名： STAT2;Signal transducer and activator of transcription 2;p113
Organism-1： Human
基因ID-1： 6773
SwissProt-1： P52630
Organism-2： Mouse
SwissProt-2： Q9WVL2
背景： The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. In response to interferon (IFN), this protein forms a complex with STAT1 and IFN regulatory factor family protein p48 (ISGF3G), in which this protein acts as a transactivator, but lacks the ability to bind DNA directly. Transcription adaptor P300/CBP (EP300/CREBBP) has been shown to interact specifically with this protein, which is thought to be involved in the process of blocking IFN-alpha response by adenovirus. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010],
細胞定位： Cytoplasm, Nucleus
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