儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
克隆性： Monoclonal
克隆號： PT0665R
特異性： Endogenous
基因名稱： CEBPA
蛋白名稱： CCAAT/enhancer-binding protein alpha
別名： CEBPA;CCAAT/enhancer-binding protein alpha;C/EBP alpha
Organism-1： Human
基因ID-1： 1050
SwissProt-1： P49715
Organism-2： Mouse
基因ID-2： 12606
SwissProt-2： P53566
Organism-3： Rat
基因ID-3： 24252
SwissProt-3： P05554
背景： This intronless gene encodes a transcription factor that contains a basic leucine zipper (bZIP) domain and recognizes the CCAAT motif in the promoters of target genes. The encoded protein functions in homodimers and also heterodimers with CCAAT/enhancer-binding proteins beta and gamma. Activity of this protein can modulate the expression of genes involved in cell cycle regulation as well as in body weight homeostasis. Mutation of this gene is associated with acute myeloid leukemia. The use of alternative in-frame non-AUG (GUG) and AUG start codons results in protein isoforms with different lengths. Differential translation initiation is mediated by an out-of-frame, upstream open reading frame which is located between the GUG and the first AUG start codons. [provided by RefSeq, Dec 2013],
儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
克隆性： Monoclonal
克隆號： PT0665R
特異性： Endogenous
基因名稱： CEBPA
蛋白名稱： CCAAT/enhancer-binding protein alpha
別名： CEBPA;CCAAT/enhancer-binding protein alpha;C/EBP alpha
Organism-1： Human
基因ID-1： 1050
SwissProt-1： P49715
Organism-2： Mouse
基因ID-2： 12606
SwissProt-2： P53566
Organism-3： Rat
基因ID-3： 24252
SwissProt-3： P05554
背景： This intronless gene encodes a transcription factor that contains a basic leucine zipper (bZIP) domain and recognizes the CCAAT motif in the promoters of target genes. The encoded protein functions in homodimers and also heterodimers with CCAAT/enhancer-binding proteins beta and gamma. Activity of this protein can modulate the expression of genes involved in cell cycle regulation as well as in body weight homeostasis. Mutation of this gene is associated with acute myeloid leukemia. The use of alternative in-frame non-AUG (GUG) and AUG start codons results in protein isoforms with different lengths. Differential translation initiation is mediated by an out-of-frame, upstream open reading frame which is located between the GUG and the first AUG start codons. [provided by RefSeq, Dec 2013],
細胞定位： Nucleus
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