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UBL4A rabbit pAb

商品貨號： PLA021520

適應(yīng) 性： 人,小鼠,大鼠

￥600元

規(guī)格：

40μL 100μL 200μL

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MSDS

說明書

商品描述

基因名稱： UBL4A DXS254E GDX UBL4
蛋白名稱： Ubiquitin-like protein 4A (Ubiquitin-like protein GDX)
Human_gene_id： 8266
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=8266
Human_swiss_prot_no： P11441
Human_swiss_link： https://www.uniprot.org/uniprotkb/P11441/entry
Mouse_gene_id： 27643
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=27643
Mouse_swiss_prot_no： P21126
Mouse_swiss_link： https://www.uniprot.org/uniprotkb/P21126/entry
Rat_gene_id： 293864
Rat_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=293864
Rat_swiss_prot_no： B2GV38
Rat_swiss_link： https://www.uniprot.org/uniprotkb/B2GV38/entry
特異性： This antibody detects endogenous levels of UBL4A at Human, Mouse,Rat
組成： Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
來源： Polyclonal, Rabbit,IgG
稀釋： WB 1:500-2000 IHC 1:50-200
純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度： 1 mg/ml
儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
說明書： 1
Msds： MSDS_Antibody.pdf
其他名稱： Ubiquitin-like protein 4A (Ubiquitin-like protein GDX)
分子量： 17kD
功能： As part of a cytosolic protein quality control complex, the BAG6/BAT3 complex, maintains misfolded and hydrophobic patches-containing proteins in a soluble state and participates in their proper delivery to the endoplasmic reticulum or alternatively can promote their sorting to the proteasome where they undergo degradation . The BAG6/BAT3 complex is involved in the post-translational delivery of tail-anchored/type II transmembrane proteins to the endoplasmic reticulum membrane. Recruited to ribosomes, it interacts with the transmembrane region of newly synthesized tail-anchored proteins and together with SGTA and ASNA1 mediates their delivery to the endoplasmic reticulum . Client proteins that cannot be properly delivered to the endoplasmic reticulum are ubiquitinated and sorted to the proteasome . Similarly, the BAG6/BAT3 complex also functions as a sorting platform for proteins of the secretory pathway that are mislocalized to the cytosol either delivering them to the proteasome for degradation or to the endoplasmic reticulum . The BAG6/BAT3 complex also plays a role in the endoplasmic reticulum-associated degradation (ERAD), a quality control mechanism that eliminates unwanted proteins of the endoplasmic reticulum through their retrotranslocation to the cytosol and their targeting to the proteasome. It maintains these retrotranslocated proteins in an unfolded yet soluble state condition in the cytosol to ensure their proper delivery to the proteasome .
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： Cytoplasm, cytosol . Nucleus .
科研貨號： PLA021520

UBL4A rabbit pAb

Catalog No PLA021520

Product information

基因名稱： UBL4A DXS254E GDX UBL4
蛋白名稱： Ubiquitin-like protein 4A (Ubiquitin-like protein GDX)
Human_gene_id： 8266
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=8266
Human_swiss_prot_no： P11441
Human_swiss_link： https://www.uniprot.org/uniprotkb/P11441/entry
Mouse_gene_id： 27643
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=27643
Mouse_swiss_prot_no： P21126
Mouse_swiss_link： https://www.uniprot.org/uniprotkb/P21126/entry
Rat_gene_id： 293864
Rat_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=293864
Rat_swiss_prot_no： B2GV38
Rat_swiss_link： https://www.uniprot.org/uniprotkb/B2GV38/entry
特異性： This antibody detects endogenous levels of UBL4A at Human, Mouse,Rat
組成： Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
來源： Polyclonal, Rabbit,IgG
稀釋： WB 1:500-2000 IHC 1:50-200
純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度： 1 mg/ml
儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
說明書： 1
Msds： MSDS_Antibody.pdf
其他名稱： Ubiquitin-like protein 4A (Ubiquitin-like protein GDX)
分子量： 17kD
功能： As part of a cytosolic protein quality control complex, the BAG6/BAT3 complex, maintains misfolded and hydrophobic patches-containing proteins in a soluble state and participates in their proper delivery to the endoplasmic reticulum or alternatively can promote their sorting to the proteasome where they undergo degradation . The BAG6/BAT3 complex is involved in the post-translational delivery of tail-anchored/type II transmembrane proteins to the endoplasmic reticulum membrane. Recruited to ribosomes, it interacts with the transmembrane region of newly synthesized tail-anchored proteins and together with SGTA and ASNA1 mediates their delivery to the endoplasmic reticulum . Client proteins that cannot be properly delivered to the endoplasmic reticulum are ubiquitinated and sorted to the proteasome . Similarly, the BAG6/BAT3 complex also functions as a sorting platform for proteins of the secretory pathway that are mislocalized to the cytosol either delivering them to the proteasome for degradation or to the endoplasmic reticulum . The BAG6/BAT3 complex also plays a role in the endoplasmic reticulum-associated degradation (ERAD), a quality control mechanism that eliminates unwanted proteins of the endoplasmic reticulum through their retrotranslocation to the cytosol and their targeting to the proteasome. It maintains these retrotranslocated proteins in an unfolded yet soluble state condition in the cytosol to ensure their proper delivery to the proteasome .
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： Cytoplasm, cytosol . Nucleus .
科研貨號： PLA021520

Hunan UPT Biotechnology Co.,Ltd

Website：m.tjdqdt.com Servive hotline :4006916686

E-mail：service@uptbio.com

Address：

Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.

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