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GREM1 rabbit pAb

商品貨號(hào)： PLA021517

適應(yīng) 性： 人,小鼠,大鼠

￥600元

規(guī)格：

40μL 100μL 200μL

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MSDS

說(shuō)明書

商品描述

基因名稱： GREM1 CKTSF1B1 DAND2 DRM PIG2
蛋白名稱： Gremlin-1 (Cell proliferation-inducing gene 2 protein) (Cysteine knot superfamily 1, BMP antagonist 1) (DAN domain family member 2) (Down-regulated in Mos-transformed cells protein) (Increased in high glucose protein 2) (IHG-2)
Human_gene_id： 26585
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=26585
Human_swiss_prot_no： O60565
Human_swiss_link： https://www.uniprot.org/uniprotkb/O60565/entry
Mouse_gene_id： 23892
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=23892
Mouse_swiss_prot_no： O70326
Mouse_swiss_link： https://www.uniprot.org/uniprotkb/O70326/entry
Rat_gene_id： 50566
Rat_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=50566
Rat_swiss_prot_no： O35793
Rat_swiss_link： https://www.uniprot.org/uniprotkb/O35793/entry
特異性： This antibody detects endogenous levels of GREM1 at Human, Mouse,Rat
組成： Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
來(lái)源： Polyclonal, Rabbit,IgG
稀釋： WB 1:500-2000 IHC 1:50-200
純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度： 1 mg/ml
儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
說(shuō)明書： 1
Msds： MSDS_Antibody.pdf
其他名稱： Gremlin-1 (Cell proliferation-inducing gene 2 protein) (Cysteine knot superfamily 1, BMP antagonist 1) (DAN domain family member 2) (Down-regulated in Mos-transformed cells protein) (Increased in high glucose protein 2) (IHG-2)
分子量： 20kD
功能： Cytokine that may play an important role during carcinogenesis and metanephric kidney organogenesis, as a BMP antagonist required for early limb outgrowth and patterning in maintaining the FGF4-SHH feedback loop. Down-regulates the BMP4 signaling in a dose-dependent manner (By similarity). Antagonist of BMP2; inhibits BMP2-mediated differentiation of osteoblasts (in vitro) . Acts as inhibitor of monocyte chemotaxis. Can inhibit the growth or viability of normal cells but not transformed cells when is overexpressed (By similarity).
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： Secreted .
組織表達(dá)： Highly expressed in small intestine, fetal brain and colon. Expression is restricted to intestinal subepithelial myofibroblasts (ISEMFs) at the crypt base. In subjects with HMPS1, by contrast, GREM1 is expressed, not only in basal ISEMFs, but also at very high levels in epithelial cells (predominantly colonocytes), with expression extending most of the way up the sides of the crypt. Weakly expressed in brain, ovary, prostate, pancreas and skeletal muscle. In brain found in the region localized around the internal capsule in the large subcortical nuclei, including caudate, putamen, substantia nigra, thalamus and subthalamus. Predominantly expressed in normal cells including neurons, astrocytes and fibroblasts.
科研貨號(hào)： PLA021517

GREM1 rabbit pAb

Catalog No PLA021517

Product information

基因名稱： GREM1 CKTSF1B1 DAND2 DRM PIG2
蛋白名稱： Gremlin-1 (Cell proliferation-inducing gene 2 protein) (Cysteine knot superfamily 1, BMP antagonist 1) (DAN domain family member 2) (Down-regulated in Mos-transformed cells protein) (Increased in high glucose protein 2) (IHG-2)
Human_gene_id： 26585
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=26585
Human_swiss_prot_no： O60565
Human_swiss_link： https://www.uniprot.org/uniprotkb/O60565/entry
Mouse_gene_id： 23892
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=23892
Mouse_swiss_prot_no： O70326
Mouse_swiss_link： https://www.uniprot.org/uniprotkb/O70326/entry
Rat_gene_id： 50566
Rat_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=50566
Rat_swiss_prot_no： O35793
Rat_swiss_link： https://www.uniprot.org/uniprotkb/O35793/entry
特異性： This antibody detects endogenous levels of GREM1 at Human, Mouse,Rat
組成： Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
來(lái)源： Polyclonal, Rabbit,IgG
稀釋： WB 1:500-2000 IHC 1:50-200
純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度： 1 mg/ml
儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
說(shuō)明書： 1
Msds： MSDS_Antibody.pdf
其他名稱： Gremlin-1 (Cell proliferation-inducing gene 2 protein) (Cysteine knot superfamily 1, BMP antagonist 1) (DAN domain family member 2) (Down-regulated in Mos-transformed cells protein) (Increased in high glucose protein 2) (IHG-2)
分子量： 20kD
功能： Cytokine that may play an important role during carcinogenesis and metanephric kidney organogenesis, as a BMP antagonist required for early limb outgrowth and patterning in maintaining the FGF4-SHH feedback loop. Down-regulates the BMP4 signaling in a dose-dependent manner (By similarity). Antagonist of BMP2; inhibits BMP2-mediated differentiation of osteoblasts (in vitro) . Acts as inhibitor of monocyte chemotaxis. Can inhibit the growth or viability of normal cells but not transformed cells when is overexpressed (By similarity).
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： Secreted .
組織表達(dá)： Highly expressed in small intestine, fetal brain and colon. Expression is restricted to intestinal subepithelial myofibroblasts (ISEMFs) at the crypt base. In subjects with HMPS1, by contrast, GREM1 is expressed, not only in basal ISEMFs, but also at very high levels in epithelial cells (predominantly colonocytes), with expression extending most of the way up the sides of the crypt. Weakly expressed in brain, ovary, prostate, pancreas and skeletal muscle. In brain found in the region localized around the internal capsule in the large subcortical nuclei, including caudate, putamen, substantia nigra, thalamus and subthalamus. Predominantly expressed in normal cells including neurons, astrocytes and fibroblasts.
科研貨號(hào)： PLA021517

Hunan UPT Biotechnology Co.,Ltd

Website：m.tjdqdt.com Servive hotline :4006916686

E-mail：service@uptbio.com

Address：

Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.

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