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Centaurin-β1 rabbit pAb

商品貨號(hào)： PLA021274

適應(yīng) 性： 人,大鼠,小鼠,

￥600元

規(guī)格：

40μL 100μL 200μL

在線咨詢(xún)

MSDS

說(shuō)明書(shū)

商品描述

基因名稱(chēng)： ACAP1 CENTB1 KIAA0050
蛋白名稱(chēng)： Centaurin-β1
Human_gene_id： 9744
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=9744
Human_swiss_prot_no： Q15027
Human_swiss_link： https://www.uniprot.org/uniprotkb/Q15027/entry
Mouse_gene_id： 216859
Mouse_gene_link： https://www.uniprot.org/uniprot/216859
Mouse_swiss_prot_no： Q8K2H4
Mouse_swiss_link： https://www.uniprot.org/uniprotkb/Q8K2H4
特異性： This antibody detects endogenous levels of Human Centaurin-β1
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來(lái)源： Polyclonal, Rabbit,IgG
稀釋?zhuān)? WB 1:1000-2000 ELISA 1:5000-20000
純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度： 1 mg/ml
儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
說(shuō)明書(shū)： 1
Msds： MSDS_Antibody.pdf
其他名稱(chēng)： Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 (Centaurin-beta-1;Cnt-b1)
分子量： 81kD
功能： domain:PH domain binds phospholipids including phosphatidic acid, phosphatidylinositol 3-phosphate, phosphatidylinositol 3,5-bisphosphate (PIP2) and phosphatidylinositol 3,4,5-trisphosphate (PIP3). May mediate ACAP1-binding to PIP2 or PIP3 containing membranes.,enzyme regulation:GAP activity stimulated by phosphatidylinositol 4,5-bisphosphate (PIP2) and phosphatidic acid.,function:GTPase-activating protein (GAP) for ADP ribosylation factor 6 (ARF6) required for clathrin-dependent export of proteins from recycling endosomes to trans-Golgi network and cell surface.,miscellaneous:Cells overexpressing ACAP1 show an accumulation of ITGB1 in recycling endosomes and inhibition of stimulation-dependent cell migration. Cells with reduced levels of ACAP1 or AKT1 and AKT2 show inhibition of stimulation-dependent cell migration. Cells overexpressing ACAP1 and PIP5K1C show formation of tubular structures derived from endosomal membranes.,PTM:Phosphorylation at Ser-554 by PKB is required for interaction with ITGB1, export of ITGB1 from recycling endosomes to the cell surface and ITGB1-dependent cell migration.,similarity:Contains 1 Arf-GAP domain.,similarity:Contains 1 BAR domain.,similarity:Contains 1 PH domain.,similarity:Contains 3 ANK repeats.,subunit:Interacts with GTP-bound ARF6. Interacts with third cytoplasmic loop of SLC2A4/GLUT4. Interacts with CLTC. Interacts with GULP1. Forms a complex with GDP-bound ARF6 and GULP1.,tissue specificity:Highest level in lung and spleen. Low level in heart, kidney, liver and pancreas.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3286
細(xì)胞定位： Recycling endosome membrane ; Peripheral membrane protein ; Cytoplasmic side .
組織表達(dá)： Highest level in lung and spleen. Low level in heart, kidney, liver and pancreas.
科研貨號(hào)： PLA021274

Centaurin-β1 rabbit pAb

Catalog No PLA021274

Product information

基因名稱(chēng)： ACAP1 CENTB1 KIAA0050
蛋白名稱(chēng)： Centaurin-β1
Human_gene_id： 9744
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=9744
Human_swiss_prot_no： Q15027
Human_swiss_link： https://www.uniprot.org/uniprotkb/Q15027/entry
Mouse_gene_id： 216859
Mouse_gene_link： https://www.uniprot.org/uniprot/216859
Mouse_swiss_prot_no： Q8K2H4
Mouse_swiss_link： https://www.uniprot.org/uniprotkb/Q8K2H4
特異性： This antibody detects endogenous levels of Human Centaurin-β1
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來(lái)源： Polyclonal, Rabbit,IgG
稀釋?zhuān)? WB 1:1000-2000 ELISA 1:5000-20000
純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度： 1 mg/ml
儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
說(shuō)明書(shū)： 1
Msds： MSDS_Antibody.pdf
其他名稱(chēng)： Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 (Centaurin-beta-1;Cnt-b1)
分子量： 81kD
功能： domain:PH domain binds phospholipids including phosphatidic acid, phosphatidylinositol 3-phosphate, phosphatidylinositol 3,5-bisphosphate (PIP2) and phosphatidylinositol 3,4,5-trisphosphate (PIP3). May mediate ACAP1-binding to PIP2 or PIP3 containing membranes.,enzyme regulation:GAP activity stimulated by phosphatidylinositol 4,5-bisphosphate (PIP2) and phosphatidic acid.,function:GTPase-activating protein (GAP) for ADP ribosylation factor 6 (ARF6) required for clathrin-dependent export of proteins from recycling endosomes to trans-Golgi network and cell surface.,miscellaneous:Cells overexpressing ACAP1 show an accumulation of ITGB1 in recycling endosomes and inhibition of stimulation-dependent cell migration. Cells with reduced levels of ACAP1 or AKT1 and AKT2 show inhibition of stimulation-dependent cell migration. Cells overexpressing ACAP1 and PIP5K1C show formation of tubular structures derived from endosomal membranes.,PTM:Phosphorylation at Ser-554 by PKB is required for interaction with ITGB1, export of ITGB1 from recycling endosomes to the cell surface and ITGB1-dependent cell migration.,similarity:Contains 1 Arf-GAP domain.,similarity:Contains 1 BAR domain.,similarity:Contains 1 PH domain.,similarity:Contains 3 ANK repeats.,subunit:Interacts with GTP-bound ARF6. Interacts with third cytoplasmic loop of SLC2A4/GLUT4. Interacts with CLTC. Interacts with GULP1. Forms a complex with GDP-bound ARF6 and GULP1.,tissue specificity:Highest level in lung and spleen. Low level in heart, kidney, liver and pancreas.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3286
細(xì)胞定位： Recycling endosome membrane ; Peripheral membrane protein ; Cytoplasmic side .
組織表達(dá)： Highest level in lung and spleen. Low level in heart, kidney, liver and pancreas.
科研貨號(hào)： PLA021274

Hunan UPT Biotechnology Co.,Ltd

Website：m.tjdqdt.com Servive hotline :4006916686

E-mail：service@uptbio.com

Address：

Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.

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