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DAZ1 rabbit pAb

商品貨號(hào)： PLA021262

適應(yīng) 性： 人,大鼠,小鼠,

￥600元

規(guī)格：

40μL 100μL 200μL

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MSDS

說明書

商品描述

基因名稱： DAZ1 DAZ SPGY
蛋白名稱： DAZ1
Human_gene_id： 1617
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=1617
Human_swiss_prot_no： Q9NQZ3
Human_swiss_link： https://www.uniprot.org/uniprotkb/Q9NQZ3/entry
特異性： This antibody detects endogenous levels of DAZ1 at Human
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來源： Polyclonal, Rabbit,IgG
稀釋： WB 1：500-2000
純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度： 1 mg/ml
儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
說明書： 1
Msds： MSDS_Antibody.pdf
分子量： 82kD
功能： caution:DAZ4 is the only DAZ gene whose expression has not been clearly demonstrated. PubMed:10936047 could not exclude the possibility that the transcript they isolated derives from DAZ1.,disease:AZFc deletions in the Yq11.23 region, including the DAZ genes, are a cause of azoospermia or oligospermia. They lead to male infertility due to impaired spermatogenesis and are found 2-10% of azoospermic or severe oligospermic males.,disease:AZFc deletions in the Yq11.23 region, including the DAZ genes, are a cause of azoospermia or oligospermia. They lead to male infertility due to impaired spermatogenesis and are found 2-10% of azoospermic or severe oligospermic males. Some AZFc deletions remove only the DAZ and DAZ2 genes and cause severe oligozoospermia.,domain:The DAZ-like repeats are essential and mediate the interaction with DAZAP1 and DAZAP2.,function:RNA-binding protein that plays an essential role in spermatogenesis. May act by binding to the 3'-UTR of mRNAs and regulating their translation.,miscellaneous:The DAZ proteins (DAZ, DAZ2, DAZ4 and DAZ4) are all encoded by a strongly repeated region of the Y chromosome, in two clusters each comprising an inverted pair of DAZ genes. They are very similar, which gives their indidual characterization difficult. Thus, most experiments do not discriminate between the different members. One can therefore suppose that reported interactions with a DAZ protein involve all the 4 proteins.,polymorphism:The number as well as the precise structure of the DAZ proteins probably differs within the population.,similarity:Belongs to the RRM DAZ family.,similarity:Contains 1 RRM (RNA recognition motif) domain.,similarity:Contains 12 DAZ-like domains.,similarity:Contains 15 DAZ-like domains.,similarity:Contains 2 RRM (RNA recognition motif) domains.,similarity:Contains 3 RRM (RNA recognition motif) domains.,similarity:Contains 9 DAZ-like domains.,subcellular location:Predominantly cytoplasmic. Nuclear at some stages of spermatozoide development. Localizes both to the nuclei and cytoplasm of spermatozoide differentiation. Nuclear in fetal gonocytes and in spermatogonial nuclei. It then relocates to the cytoplasm during male meiosis.,subunit:Forms a heterodimer with BOLL and DAZL. Interacts with PUM2, DAZAP1, DAZAP2, DZIP1 and DZIP3.,tissue specificity:Testis specific.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： Cytoplasm . Nucleus . Predominantly cytoplasmic. Nuclear at some stages of spermatozoide development. Localizes both to the nuclei and cytoplasm of spermatozoide differentiation. Nuclear in fetal gonocytes and in spermatogonial nuclei. It then relocates to the cytoplasm during male meiosis.
組織表達(dá)： Testis-specific. Expression restricted to premeiotic germ cells, particularly in spermatogonia (at protein level).
科研貨號(hào)： PLA021262

DAZ1 rabbit pAb

Catalog No PLA021262

Product information

基因名稱： DAZ1 DAZ SPGY
蛋白名稱： DAZ1
Human_gene_id： 1617
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=1617
Human_swiss_prot_no： Q9NQZ3
Human_swiss_link： https://www.uniprot.org/uniprotkb/Q9NQZ3/entry
特異性： This antibody detects endogenous levels of DAZ1 at Human
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來源： Polyclonal, Rabbit,IgG
稀釋： WB 1：500-2000
純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度： 1 mg/ml
儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
說明書： 1
Msds： MSDS_Antibody.pdf
分子量： 82kD
功能： caution:DAZ4 is the only DAZ gene whose expression has not been clearly demonstrated. PubMed:10936047 could not exclude the possibility that the transcript they isolated derives from DAZ1.,disease:AZFc deletions in the Yq11.23 region, including the DAZ genes, are a cause of azoospermia or oligospermia. They lead to male infertility due to impaired spermatogenesis and are found 2-10% of azoospermic or severe oligospermic males.,disease:AZFc deletions in the Yq11.23 region, including the DAZ genes, are a cause of azoospermia or oligospermia. They lead to male infertility due to impaired spermatogenesis and are found 2-10% of azoospermic or severe oligospermic males. Some AZFc deletions remove only the DAZ and DAZ2 genes and cause severe oligozoospermia.,domain:The DAZ-like repeats are essential and mediate the interaction with DAZAP1 and DAZAP2.,function:RNA-binding protein that plays an essential role in spermatogenesis. May act by binding to the 3'-UTR of mRNAs and regulating their translation.,miscellaneous:The DAZ proteins (DAZ, DAZ2, DAZ4 and DAZ4) are all encoded by a strongly repeated region of the Y chromosome, in two clusters each comprising an inverted pair of DAZ genes. They are very similar, which gives their indidual characterization difficult. Thus, most experiments do not discriminate between the different members. One can therefore suppose that reported interactions with a DAZ protein involve all the 4 proteins.,polymorphism:The number as well as the precise structure of the DAZ proteins probably differs within the population.,similarity:Belongs to the RRM DAZ family.,similarity:Contains 1 RRM (RNA recognition motif) domain.,similarity:Contains 12 DAZ-like domains.,similarity:Contains 15 DAZ-like domains.,similarity:Contains 2 RRM (RNA recognition motif) domains.,similarity:Contains 3 RRM (RNA recognition motif) domains.,similarity:Contains 9 DAZ-like domains.,subcellular location:Predominantly cytoplasmic. Nuclear at some stages of spermatozoide development. Localizes both to the nuclei and cytoplasm of spermatozoide differentiation. Nuclear in fetal gonocytes and in spermatogonial nuclei. It then relocates to the cytoplasm during male meiosis.,subunit:Forms a heterodimer with BOLL and DAZL. Interacts with PUM2, DAZAP1, DAZAP2, DZIP1 and DZIP3.,tissue specificity:Testis specific.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： Cytoplasm . Nucleus . Predominantly cytoplasmic. Nuclear at some stages of spermatozoide development. Localizes both to the nuclei and cytoplasm of spermatozoide differentiation. Nuclear in fetal gonocytes and in spermatogonial nuclei. It then relocates to the cytoplasm during male meiosis.
組織表達(dá)： Testis-specific. Expression restricted to premeiotic germ cells, particularly in spermatogonia (at protein level).
科研貨號(hào)： PLA021262

Hunan UPT Biotechnology Co.,Ltd

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E-mail：service@uptbio.com

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