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PRGC2 rabbit pAb

商品貨號(hào)： PLA021226

適應(yīng) 性： 人,小鼠,大鼠

￥600元

規(guī)格：

40μL 100μL 200μL

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MSDS

說明書

商品描述

基因名稱： PPARGC1B PERC PGC1 PGC1B PPARGC1
蛋白名稱： PRGC2
Human_gene_id： 133522
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=133522
Human_swiss_prot_no： Q86YN6
Human_swiss_link： https://www.uniprot.org/uniprotkb/Q86YN6/entry
Mouse_gene_id： 170826
Mouse_gene_link： https://www.uniprot.org/uniprot/170826
Mouse_swiss_prot_no： Q8VHJ7
Mouse_swiss_link： https://www.uniprot.org/uniprotkb/Q8VHJ7
Rat_gene_id： 291567
Rat_gene_link： https://www.uniprot.org/uniprot/291567
Rat_swiss_prot_no： Q811R2
Rat_swiss_link： https://www.uniprot.org/uniprotkb/Q811R2
特異性： This antibody detects endogenous levels of PRGC2 at Human/Mouse/Rat
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來源： Polyclonal, Rabbit,IgG
稀釋： WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度： 1 mg/ml
儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
說明書： 1
Msds： MSDS_Antibody.pdf
分子量： 113kD
功能： domain:Contains 2 Leu-Xaa-Xaa-Leu-Leu (LXXLL) motif, which are usually required for the association with nuclear receptors.,function:Plays a role of stimulator of transcription factors and nuclear receptors activities. Activates transcritional activity of estrogen receptor alpha, nuclear respiratory factor 1 (NRF1) and glucocorticoid receptor in the presence of glucocorticoids. May play a role in constitutive non-adrenergic-mediated mitochondrial biogenesis as suggested by increased basal oxygen consumption and mitochondrial number when overexpressed. May be involved in fat oxidation and non-oxidative glucose metabolism and in the regulation of energy expenditure.,induction:Repressed by saturated fatty acids such as palmitate and stearate in skeletal muscle cells. Induced by insulin and reduced by aging in skeletal muscle biopsies. Down-regulated in type 2 diabetes mellitus subjects as well as in pre-diabetics.,polymorphism:Variation of PPARGC1B may contribute to the pathogenesis of obesity, with a widespread Ala-203 allele being a risk factor for the development of this common disorders.,similarity:Contains 1 RRM (RNA recognition motif) domain.,subunit:Interacts with hepatocyte nuclear factor 4-alpha/HNF4A, Sterol regulatory binding transcription factor 1/SREBF1, PPAR-alpha/PPARA, thyroid hormone receptor beta/THRB and host cell factor/HCFC1. Interacts with estrogen-related receptor gamma/ESRRG and alpha/ESRRA (By similarity). Interacts with estrogen receptor alpha/ESR1.,tissue specificity:Ubiquitous with higher expression in heart, brain and skeletal muscle.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： Nucleus .
組織表達(dá)： Ubiquitous with higher expression in heart, brain and skeletal muscle.
科研貨號(hào)： PLA021226

PRGC2 rabbit pAb

Catalog No PLA021226

Product information

基因名稱： PPARGC1B PERC PGC1 PGC1B PPARGC1
蛋白名稱： PRGC2
Human_gene_id： 133522
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=133522
Human_swiss_prot_no： Q86YN6
Human_swiss_link： https://www.uniprot.org/uniprotkb/Q86YN6/entry
Mouse_gene_id： 170826
Mouse_gene_link： https://www.uniprot.org/uniprot/170826
Mouse_swiss_prot_no： Q8VHJ7
Mouse_swiss_link： https://www.uniprot.org/uniprotkb/Q8VHJ7
Rat_gene_id： 291567
Rat_gene_link： https://www.uniprot.org/uniprot/291567
Rat_swiss_prot_no： Q811R2
Rat_swiss_link： https://www.uniprot.org/uniprotkb/Q811R2
特異性： This antibody detects endogenous levels of PRGC2 at Human/Mouse/Rat
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來源： Polyclonal, Rabbit,IgG
稀釋： WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度： 1 mg/ml
儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
說明書： 1
Msds： MSDS_Antibody.pdf
分子量： 113kD
功能： domain:Contains 2 Leu-Xaa-Xaa-Leu-Leu (LXXLL) motif, which are usually required for the association with nuclear receptors.,function:Plays a role of stimulator of transcription factors and nuclear receptors activities. Activates transcritional activity of estrogen receptor alpha, nuclear respiratory factor 1 (NRF1) and glucocorticoid receptor in the presence of glucocorticoids. May play a role in constitutive non-adrenergic-mediated mitochondrial biogenesis as suggested by increased basal oxygen consumption and mitochondrial number when overexpressed. May be involved in fat oxidation and non-oxidative glucose metabolism and in the regulation of energy expenditure.,induction:Repressed by saturated fatty acids such as palmitate and stearate in skeletal muscle cells. Induced by insulin and reduced by aging in skeletal muscle biopsies. Down-regulated in type 2 diabetes mellitus subjects as well as in pre-diabetics.,polymorphism:Variation of PPARGC1B may contribute to the pathogenesis of obesity, with a widespread Ala-203 allele being a risk factor for the development of this common disorders.,similarity:Contains 1 RRM (RNA recognition motif) domain.,subunit:Interacts with hepatocyte nuclear factor 4-alpha/HNF4A, Sterol regulatory binding transcription factor 1/SREBF1, PPAR-alpha/PPARA, thyroid hormone receptor beta/THRB and host cell factor/HCFC1. Interacts with estrogen-related receptor gamma/ESRRG and alpha/ESRRA (By similarity). Interacts with estrogen receptor alpha/ESR1.,tissue specificity:Ubiquitous with higher expression in heart, brain and skeletal muscle.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： Nucleus .
組織表達(dá)： Ubiquitous with higher expression in heart, brain and skeletal muscle.
科研貨號(hào)： PLA021226

Hunan UPT Biotechnology Co.,Ltd

Website：m.tjdqdt.com Servive hotline :4006916686

E-mail：service@uptbio.com

Address：

Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.

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