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K2C75 rabbit pAb

商品貨號(hào)： PLA021195

適應(yīng) 性： 人,小鼠,大鼠

￥600元

規(guī)格：

40μL 100μL 200μL

在線咨詢

MSDS

說(shuō)明書(shū)

商品描述

基因名稱(chēng)： KRT75 K6HF KB18
蛋白名稱(chēng)： K2C75
Human_gene_id： 9119
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=9119
Human_swiss_prot_no： O95678
Human_swiss_link： https://www.uniprot.org/uniprotkb/O95678/entry
Mouse_gene_id： 109052
Mouse_gene_link： https://www.uniprot.org/uniprot/109052
Mouse_swiss_prot_no： Q8BGZ7
Mouse_swiss_link： https://www.uniprot.org/uniprotkb/Q8BGZ7
Rat_gene_id： 300247
Rat_gene_link： https://www.uniprot.org/uniprot/300247
Rat_swiss_prot_no： Q6IG05
Rat_swiss_link： https://www.uniprot.org/uniprotkb/Q6IG05
特異性： This antibody detects endogenous levels of K2C75 at Human/Mouse/Rat
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來(lái)源： Polyclonal, Rabbit,IgG
稀釋?zhuān)? WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度： 1 mg/ml
儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
說(shuō)明書(shū)： 1
Msds： MSDS_Antibody.pdf
分子量： 61kD
功能： disease:Defects in KRT75 may be a cause of loose anagen hair syndrome (LAHS) [MIM:600628]. In LAHS, anagen hairs are easily pulled from the scalp. The hair is relatively sparse and does not grow long. Hair of fair color and hair shafts of reduced caliber, and an early age of onset are features. Usually the hairs are not fragile and there are no areas of breakage.,function:Plays a central role in hair and nail formation. Essential component of keratin intermediate filaments in the companion layer of the hair follicle.,miscellaneous:May be used as a marker of hair differentiation.,miscellaneous:There are two types of cytoskeletal and microfibrillar keratin, I (acidic) and II (neutral to basic) (40-55 and 56-70 kDa, respectively).,polymorphism:The Thr-161 variant may increase risk to develop pseudofolliculitis barbae (PFB) [MIM:612318]. PFB is a common hair disorder characterized by a pustular foreign body inflammatory reaction that is induced by ingrown hairs of the facial and submental (barbea) regions after regular shaving. It occurs predominantly in black males, while it is rather rare and usually far less severe in Caucasian males.,similarity:Belongs to the intermediate filament family.,subunit:Heterodimer of a type I and a type II keratin (By similarity). May associate with KRT17.,tissue specificity:Highly expressed in hair follicles from scalp. Specifically expressed in the of the hair companion layer follicle, a single layered band of flat and vertically oriented cells between the cuboidal outer root sheath (ORS) cells and the inner root sheath (IRS) that stretches from the lowermost bulb region to the isthmus of the follicle. Also expressed in medullated hairs. In nails, it is almost exclusively present in the nail bed (at protein level).,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： intermediate filament,keratin filament,extracellular exosome,
組織表達(dá)： Highly expressed in hair follicles from scalp. Specifically expressed in the of the hair companion layer follicle, a single layered band of flat and vertically oriented cells between the cuboidal outer root sheath (ORS) cells and the inner root sheath (IRS) that stretches from the lowermost bulb region to the isthmus of the follicle. Also expressed in medullated hairs. In nails, it is almost exclusively present in the nail bed (at protein level).
科研貨號(hào)： PLA021195

K2C75 rabbit pAb

Catalog No PLA021195

Product information

基因名稱(chēng)： KRT75 K6HF KB18
蛋白名稱(chēng)： K2C75
Human_gene_id： 9119
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=9119
Human_swiss_prot_no： O95678
Human_swiss_link： https://www.uniprot.org/uniprotkb/O95678/entry
Mouse_gene_id： 109052
Mouse_gene_link： https://www.uniprot.org/uniprot/109052
Mouse_swiss_prot_no： Q8BGZ7
Mouse_swiss_link： https://www.uniprot.org/uniprotkb/Q8BGZ7
Rat_gene_id： 300247
Rat_gene_link： https://www.uniprot.org/uniprot/300247
Rat_swiss_prot_no： Q6IG05
Rat_swiss_link： https://www.uniprot.org/uniprotkb/Q6IG05
特異性： This antibody detects endogenous levels of K2C75 at Human/Mouse/Rat
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來(lái)源： Polyclonal, Rabbit,IgG
稀釋?zhuān)? WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度： 1 mg/ml
儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
說(shuō)明書(shū)： 1
Msds： MSDS_Antibody.pdf
分子量： 61kD
功能： disease:Defects in KRT75 may be a cause of loose anagen hair syndrome (LAHS) [MIM:600628]. In LAHS, anagen hairs are easily pulled from the scalp. The hair is relatively sparse and does not grow long. Hair of fair color and hair shafts of reduced caliber, and an early age of onset are features. Usually the hairs are not fragile and there are no areas of breakage.,function:Plays a central role in hair and nail formation. Essential component of keratin intermediate filaments in the companion layer of the hair follicle.,miscellaneous:May be used as a marker of hair differentiation.,miscellaneous:There are two types of cytoskeletal and microfibrillar keratin, I (acidic) and II (neutral to basic) (40-55 and 56-70 kDa, respectively).,polymorphism:The Thr-161 variant may increase risk to develop pseudofolliculitis barbae (PFB) [MIM:612318]. PFB is a common hair disorder characterized by a pustular foreign body inflammatory reaction that is induced by ingrown hairs of the facial and submental (barbea) regions after regular shaving. It occurs predominantly in black males, while it is rather rare and usually far less severe in Caucasian males.,similarity:Belongs to the intermediate filament family.,subunit:Heterodimer of a type I and a type II keratin (By similarity). May associate with KRT17.,tissue specificity:Highly expressed in hair follicles from scalp. Specifically expressed in the of the hair companion layer follicle, a single layered band of flat and vertically oriented cells between the cuboidal outer root sheath (ORS) cells and the inner root sheath (IRS) that stretches from the lowermost bulb region to the isthmus of the follicle. Also expressed in medullated hairs. In nails, it is almost exclusively present in the nail bed (at protein level).,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： intermediate filament,keratin filament,extracellular exosome,
組織表達(dá)： Highly expressed in hair follicles from scalp. Specifically expressed in the of the hair companion layer follicle, a single layered band of flat and vertically oriented cells between the cuboidal outer root sheath (ORS) cells and the inner root sheath (IRS) that stretches from the lowermost bulb region to the isthmus of the follicle. Also expressed in medullated hairs. In nails, it is almost exclusively present in the nail bed (at protein level).
科研貨號(hào)： PLA021195

Hunan UPT Biotechnology Co.,Ltd

Website：m.tjdqdt.com Servive hotline :4006916686

E-mail：service@uptbio.com

Address：

Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.

亚洲国产日韩不卡综合,明星ai换脸磁力资源种子搜索,成人性闻CCAV下载,欧美日本国产在线a小说v,亚洲欧洲综合一区二区三区,里中结衣av中文字幕