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RN139 rabbit pAb

商品貨號： PLA021152

適應(yīng) 性： 人,小鼠

￥600元

規(guī)格：

40μL 100μL 200μL

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MSDS

說明書

商品描述

基因名稱： RNF139 TRC8
蛋白名稱： RN139
Human_gene_id： 11236
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=11236
Human_swiss_prot_no： Q8WU17
Human_swiss_link： https://www.uniprot.org/uniprotkb/Q8WU17/entry
Mouse_gene_id： 75841
Mouse_gene_link： https://www.uniprot.org/uniprot/75841
Mouse_swiss_prot_no： Q7TMV1
Mouse_swiss_link： https://www.uniprot.org/uniprotkb/Q7TMV1
特異性： This antibody detects endogenous levels of RN139 at Human/Mouse
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來源： Polyclonal, Rabbit,IgG
稀釋： WB 1:500-2000;IHC-p 1:50-300
純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度： 1 mg/ml
儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
說明書： 1
Msds： MSDS_Antibody.pdf
分子量： 73kD
功能： disease:Defects in RNF139 are a cause of renal cell carcinoma (RCC) [MIM:144700]. A chromosomal aberration involving RNF139 is found in hereditary RCC. Translocation (3;8)(q14.2;q24.1) with FHIT. The result is RNF139 is found to be fused to FHIT and disrupted within the sterol-sensing domain. In contrast, the FHIT coding region is maintained and expressed. Sporadic RCC, where an acquired mutation in RNF139 results in the duplication of 12 nucleotides in the 5'-UTR, has also been identified.,domain:The RING-type zinc finger domain may be essential for ubiquitin ligase activity.,function:Potential tumor suppressor for renal cell carcinoma. Plays a role in mediating ubiquitination. May function as a signaling receptor.,similarity:Contains 1 RING-type zinc finger.,subunit:Interacts with VHL.,tissue specificity:Highly expressed in testis, placenta and adrenal gland. Moderate expression in heart, brain, liver, skeletal muscle and pancreas, and low expression in lung and kidney.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： Endoplasmic reticulum membrane ; Multi-pass membrane protein .
組織表達(dá)： Highly expressed in testis, placenta and adrenal gland. Moderate expression in heart, brain, liver, skeletal muscle and pancreas, and low expression in lung and kidney.
科研貨號： PLA021152

RN139 rabbit pAb

Catalog No PLA021152

Product information

基因名稱： RNF139 TRC8
蛋白名稱： RN139
Human_gene_id： 11236
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=11236
Human_swiss_prot_no： Q8WU17
Human_swiss_link： https://www.uniprot.org/uniprotkb/Q8WU17/entry
Mouse_gene_id： 75841
Mouse_gene_link： https://www.uniprot.org/uniprot/75841
Mouse_swiss_prot_no： Q7TMV1
Mouse_swiss_link： https://www.uniprot.org/uniprotkb/Q7TMV1
特異性： This antibody detects endogenous levels of RN139 at Human/Mouse
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來源： Polyclonal, Rabbit,IgG
稀釋： WB 1:500-2000;IHC-p 1:50-300
純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度： 1 mg/ml
儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
說明書： 1
Msds： MSDS_Antibody.pdf
分子量： 73kD
功能： disease:Defects in RNF139 are a cause of renal cell carcinoma (RCC) [MIM:144700]. A chromosomal aberration involving RNF139 is found in hereditary RCC. Translocation (3;8)(q14.2;q24.1) with FHIT. The result is RNF139 is found to be fused to FHIT and disrupted within the sterol-sensing domain. In contrast, the FHIT coding region is maintained and expressed. Sporadic RCC, where an acquired mutation in RNF139 results in the duplication of 12 nucleotides in the 5'-UTR, has also been identified.,domain:The RING-type zinc finger domain may be essential for ubiquitin ligase activity.,function:Potential tumor suppressor for renal cell carcinoma. Plays a role in mediating ubiquitination. May function as a signaling receptor.,similarity:Contains 1 RING-type zinc finger.,subunit:Interacts with VHL.,tissue specificity:Highly expressed in testis, placenta and adrenal gland. Moderate expression in heart, brain, liver, skeletal muscle and pancreas, and low expression in lung and kidney.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： Endoplasmic reticulum membrane ; Multi-pass membrane protein .
組織表達(dá)： Highly expressed in testis, placenta and adrenal gland. Moderate expression in heart, brain, liver, skeletal muscle and pancreas, and low expression in lung and kidney.
科研貨號： PLA021152

Hunan UPT Biotechnology Co.,Ltd

Website：m.tjdqdt.com Servive hotline :4006916686

E-mail：service@uptbio.com

Address：

Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.

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