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SEN15 rabbit pAb

商品貨號： PLA021076

適應(yīng) 性： 人,小鼠

￥600元

規(guī)格：

40μL 100μL 200μL

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MSDS

說明書

商品描述

基因名稱： TSEN15 C1orf19 SEN15
蛋白名稱： SEN15
Human_gene_id： 116461
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=116461
Human_swiss_prot_no： Q8WW01
Human_swiss_link： https://www.uniprot.org/uniprotkb/Q8WW01/entry
Mouse_gene_id： 66637
Mouse_gene_link： https://www.uniprot.org/uniprot/66637
Mouse_swiss_prot_no： Q8R3W5
Mouse_swiss_link： https://www.uniprot.org/uniprotkb/Q8R3W5
特異性： This antibody detects endogenous levels of SEN15 at Human/Mouse
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來源： Polyclonal, Rabbit,IgG
稀釋： WB 1:500-2000;IHC-p 1:50-300
純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度： 1 mg/ml
儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
說明書： 1
Msds： MSDS_Antibody.pdf
分子量： 19kD
功能： caution:Although only weakly related to the S.cerevisiae SEN15 protein, it probably displays the same function within the tRNA splicing endonuclease complex.,function:Non-catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5' and 3' splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA body. The tRNA splicing endonuclease is also involved in mRNA processing via its association with pre-mRNA 3' end processing factors, establishing a link between pre-tRNA splicing and pre-mRNA 3' end formation, suggesting that the endonuclease subunits function in multiple RNA-processing events.,similarity:Belongs to the SEN15 family.,subcellular location:May be transiently localized in the nucleolus.,subunit:tRNA splicing endonuclease is a heterotetramer composed of SEN2, SEN15, SEN34/LENG5 and SEN54. tRNA splicing endonuclease complex also contains proteins of the pre-mRNA 3' end processing machinery such as CLP1, CPSF1, CPSF4 and CSTF2.,tissue specificity:Widely expressed. Highly expressed in testis and uterus.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： Nucleus . Nucleus, nucleolus . May be transiently localized in the nucleolus. .
組織表達(dá)： Widely expressed. Highly expressed in testis and uterus.
科研貨號： PLA021076

SEN15 rabbit pAb

Catalog No PLA021076

Product information

基因名稱： TSEN15 C1orf19 SEN15
蛋白名稱： SEN15
Human_gene_id： 116461
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=116461
Human_swiss_prot_no： Q8WW01
Human_swiss_link： https://www.uniprot.org/uniprotkb/Q8WW01/entry
Mouse_gene_id： 66637
Mouse_gene_link： https://www.uniprot.org/uniprot/66637
Mouse_swiss_prot_no： Q8R3W5
Mouse_swiss_link： https://www.uniprot.org/uniprotkb/Q8R3W5
特異性： This antibody detects endogenous levels of SEN15 at Human/Mouse
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來源： Polyclonal, Rabbit,IgG
稀釋： WB 1:500-2000;IHC-p 1:50-300
純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度： 1 mg/ml
儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
說明書： 1
Msds： MSDS_Antibody.pdf
分子量： 19kD
功能： caution:Although only weakly related to the S.cerevisiae SEN15 protein, it probably displays the same function within the tRNA splicing endonuclease complex.,function:Non-catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5' and 3' splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA body. The tRNA splicing endonuclease is also involved in mRNA processing via its association with pre-mRNA 3' end processing factors, establishing a link between pre-tRNA splicing and pre-mRNA 3' end formation, suggesting that the endonuclease subunits function in multiple RNA-processing events.,similarity:Belongs to the SEN15 family.,subcellular location:May be transiently localized in the nucleolus.,subunit:tRNA splicing endonuclease is a heterotetramer composed of SEN2, SEN15, SEN34/LENG5 and SEN54. tRNA splicing endonuclease complex also contains proteins of the pre-mRNA 3' end processing machinery such as CLP1, CPSF1, CPSF4 and CSTF2.,tissue specificity:Widely expressed. Highly expressed in testis and uterus.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： Nucleus . Nucleus, nucleolus . May be transiently localized in the nucleolus. .
組織表達(dá)： Widely expressed. Highly expressed in testis and uterus.
科研貨號： PLA021076

Hunan UPT Biotechnology Co.,Ltd

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E-mail：service@uptbio.com

Address：

Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.

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