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MPZL1 rabbit pAb

商品貨號(hào)： PLA021040

適應(yīng) 性： 人,小鼠,大鼠

￥600元

規(guī)格：

40μL 100μL 200μL

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MSDS

說明書

商品描述

基因名稱： MPZL1 PZR UNQ849/PRO1787
蛋白名稱： MPZL1
Human_gene_id： 9019
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=9019
Human_swiss_prot_no： O95297
Human_swiss_link： https://www.uniprot.org/uniprotkb/O95297/entry
Mouse_gene_id： 68481
Mouse_gene_link： https://www.uniprot.org/uniprot/68481
Mouse_swiss_prot_no： Q3TEW6
Mouse_swiss_link： https://www.uniprot.org/uniprotkb/Q3TEW6
Rat_gene_id： 360871
Rat_gene_link： https://www.uniprot.org/uniprot/360871
Rat_swiss_prot_no： Q6AYT8
Rat_swiss_link： https://www.uniprot.org/uniprotkb/Q6AYT8
特異性： This antibody detects endogenous levels of MPZL1 at Human/Mouse/Rat
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來源： Polyclonal, Rabbit,IgG
稀釋： WB 1:500-2000;IHC-p 1:50-300
純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度： 1 mg/ml
儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
說明書： 1
Msds： MSDS_Antibody.pdf
分子量： 30kD
功能： domain:Contains 2 copies of a cytoplasmic motif that is referred to as the immunoreceptor tyrosine-based inhibitor motif (ITIM). This motif is involved in modulation of cellular responses. The phosphorylated ITIM motif can bind the SH2 domain of several SH2-containing phosphatases.,function:Cell surface receptor, which is involved in signal transduction processes. Recruits PTPN11/SHP-2 to the cell membrane and is a putative substrate of PTPN11/SHP-2. Is a major receptor for concanavalin A (ConA) and is involved in cellular signaling induced by ConA, which probably includes Src family tyrosine-protein kinases. Isoform 3 seems to have a dominant negative role; it blocks tyrosine phosphorylation of MPZL1 induced by ConA. Isoform 1, but not isoform 2 and isoform 3, may be involved in regulation of integrin-mediated cell motility.,PTM:N-glycosylated.,PTM:Phosphorylated on tyrosine residues upon stimulation with pervanadate and concanavalin A (ConA). Phosphorylation at Tyr-241 and Tyr-263 is required for interaction with PTPN11/SHP-2. Dephosphorylated by PTPN11/SHP-2 (in vitro).,similarity:Belongs to the myelin P0 protein family.,similarity:Contains 1 Ig-like V-type (immunoglobulin-like) domain.,subunit:Interacts with phosphorylated PTPN11/SHP-2.,tissue specificity:Widely expressed with highest levels in heart, placenta, kidney and pancreas. Isoform 3 is relatively abundant in hemotopoietic tissues and fetal liver. Isoform 1 and isoform 3 are expressed in CD14- PB monocytes and pre-B cell progenitors. Isoform 3 appears to be the major isoform in CD34- promyelocytic and promonocytic cells. During differentiation in monocytic cells, the expression level of isoform 3 decreases and that of isoform 1 increases. Isoform 1 is prominent in stromal cells and, to a lesser extent, in umbelical vein endothelial cells and erythroid progenitors. Isoform 2 is expressed in a erythroid progenitor cell line.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： Membrane ; Single-pass type I membrane protein .
組織表達(dá)： Widely expressed with highest levels in heart, placenta, kidney and pancreas. Isoform 3 is relatively abundant in hematopoietic tissues and fetal liver. Isoform 1 and isoform 3 are expressed in CD14- PB monocytes and pre-B cell progenitors. Isoform 3 appears to be the major isoform in CD34- promyelocytic and promonocytic cells. During differentiation in monocytic cells, the expression level of isoform 3 decreases and that of isoform 1 increases. Isoform 1 is prominent in stromal cells and, to a lesser extent, in umbilical vein endothelial cells and erythroid progenitors. Isoform 2 is expressed in a erythroid progenitor cell line.
科研貨號(hào)： PLA021040

MPZL1 rabbit pAb

Catalog No PLA021040

Product information

基因名稱： MPZL1 PZR UNQ849/PRO1787
蛋白名稱： MPZL1
Human_gene_id： 9019
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=9019
Human_swiss_prot_no： O95297
Human_swiss_link： https://www.uniprot.org/uniprotkb/O95297/entry
Mouse_gene_id： 68481
Mouse_gene_link： https://www.uniprot.org/uniprot/68481
Mouse_swiss_prot_no： Q3TEW6
Mouse_swiss_link： https://www.uniprot.org/uniprotkb/Q3TEW6
Rat_gene_id： 360871
Rat_gene_link： https://www.uniprot.org/uniprot/360871
Rat_swiss_prot_no： Q6AYT8
Rat_swiss_link： https://www.uniprot.org/uniprotkb/Q6AYT8
特異性： This antibody detects endogenous levels of MPZL1 at Human/Mouse/Rat
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來源： Polyclonal, Rabbit,IgG
稀釋： WB 1:500-2000;IHC-p 1:50-300
純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度： 1 mg/ml
儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
說明書： 1
Msds： MSDS_Antibody.pdf
分子量： 30kD
功能： domain:Contains 2 copies of a cytoplasmic motif that is referred to as the immunoreceptor tyrosine-based inhibitor motif (ITIM). This motif is involved in modulation of cellular responses. The phosphorylated ITIM motif can bind the SH2 domain of several SH2-containing phosphatases.,function:Cell surface receptor, which is involved in signal transduction processes. Recruits PTPN11/SHP-2 to the cell membrane and is a putative substrate of PTPN11/SHP-2. Is a major receptor for concanavalin A (ConA) and is involved in cellular signaling induced by ConA, which probably includes Src family tyrosine-protein kinases. Isoform 3 seems to have a dominant negative role; it blocks tyrosine phosphorylation of MPZL1 induced by ConA. Isoform 1, but not isoform 2 and isoform 3, may be involved in regulation of integrin-mediated cell motility.,PTM:N-glycosylated.,PTM:Phosphorylated on tyrosine residues upon stimulation with pervanadate and concanavalin A (ConA). Phosphorylation at Tyr-241 and Tyr-263 is required for interaction with PTPN11/SHP-2. Dephosphorylated by PTPN11/SHP-2 (in vitro).,similarity:Belongs to the myelin P0 protein family.,similarity:Contains 1 Ig-like V-type (immunoglobulin-like) domain.,subunit:Interacts with phosphorylated PTPN11/SHP-2.,tissue specificity:Widely expressed with highest levels in heart, placenta, kidney and pancreas. Isoform 3 is relatively abundant in hemotopoietic tissues and fetal liver. Isoform 1 and isoform 3 are expressed in CD14- PB monocytes and pre-B cell progenitors. Isoform 3 appears to be the major isoform in CD34- promyelocytic and promonocytic cells. During differentiation in monocytic cells, the expression level of isoform 3 decreases and that of isoform 1 increases. Isoform 1 is prominent in stromal cells and, to a lesser extent, in umbelical vein endothelial cells and erythroid progenitors. Isoform 2 is expressed in a erythroid progenitor cell line.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： Membrane ; Single-pass type I membrane protein .
組織表達(dá)： Widely expressed with highest levels in heart, placenta, kidney and pancreas. Isoform 3 is relatively abundant in hematopoietic tissues and fetal liver. Isoform 1 and isoform 3 are expressed in CD14- PB monocytes and pre-B cell progenitors. Isoform 3 appears to be the major isoform in CD34- promyelocytic and promonocytic cells. During differentiation in monocytic cells, the expression level of isoform 3 decreases and that of isoform 1 increases. Isoform 1 is prominent in stromal cells and, to a lesser extent, in umbilical vein endothelial cells and erythroid progenitors. Isoform 2 is expressed in a erythroid progenitor cell line.
科研貨號(hào)： PLA021040

Hunan UPT Biotechnology Co.,Ltd

Website：m.tjdqdt.com Servive hotline :4006916686

E-mail：service@uptbio.com

Address：

Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.

亚洲国产日韩不卡综合,明星ai换脸磁力资源种子搜索,成人性闻CCAV下载,欧美日本国产在线a小说v,亚洲欧洲综合一区二区三区,里中结衣av中文字幕