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PTF1A rabbit pAb

商品貨號(hào)： PLA020915

適應(yīng) 性： 人,小鼠,大鼠

￥600元

規(guī)格：

40μL 100μL 200μL

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MSDS

說(shuō)明書

商品描述

基因名稱： PTF1A BHLHA29 PTF1P48
蛋白名稱： PTF1A
Human_gene_id： 256297
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=256297
Human_swiss_prot_no： Q7RTS3
Human_swiss_link： https://www.uniprot.org/uniprotkb/Q7RTS3/entry
Mouse_gene_id： 19213
Mouse_gene_link： https://www.uniprot.org/uniprot/19213
Mouse_swiss_prot_no： Q9QX98
Mouse_swiss_link： https://www.uniprot.org/uniprotkb/Q9QX98
Rat_gene_id： 117034
Rat_gene_link： https://www.uniprot.org/uniprot/117034
Rat_swiss_prot_no： Q64305
Rat_swiss_link： https://www.uniprot.org/uniprotkb/Q64305
特異性： This antibody detects endogenous levels of PTF1A at Human/Mouse/Rat
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來(lái)源： Polyclonal, Rabbit,IgG
稀釋： WB 1:500-2000;IHC-p 1:50-300
純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度： 1 mg/ml
儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
說(shuō)明書： 1
Msds： MSDS_Antibody.pdf
分子量： 36kD
功能： disease:Defects in PTF1A are the cause of diabetes mellitus and cerebellar hypoplasia/agenesis [MIM:609069].,function:Transcriptional activator. Binds to the E-box consensus sequence 5'-CANNTG-3'. Plays an important role in determining whether cells allocated to the pancreatic buds continue towards pancreatic organogenesis or revert back to duodenal fates. May be involved in the maintenance of exocrine pancreas-specific gene expression including ELA1 and amylase. Required for the formation of pancreatic acinar and ductal cells (By similarity). Plays an important role in cerebellar development.,miscellaneous:An excellent marker of acinar cell differentiation in the pancreas.,similarity:Contains 1 basic helix-loop-helix (bHLH) domain.,subcellular location:In chronic pancreatitis associated with pancreas cancer preferentially accumulates in the cytoplasm of acinar/ductular complexes. In the cytoplasm loses its ability to form the PTF1 complex.,subunit:Component of the pancreas transcription factor 1 complex (PTF1) which is composed of TCF3/p75, TCF12/p64 and PTF1A/p48. TCF3 is responsible for the nuclear import of the p48/p64 complex. Interacts with TCF3 and RBPSUH/RBP-Jkappa.,tissue specificity:Pancreas-specific (at protein level). Loss of expression is seen in ductal type pancreas cancers.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： Nucleus . Cytoplasm . In chronic pancreatitis associated with pancreas cancer preferentially accumulates in the cytoplasm of acinar/ductular complexes. In the cytoplasm loses its ability to form the PTF1 complex (By similarity). .
組織表達(dá)： Pancreas-specific (at protein level). Loss of expression is seen in ductal type pancreas cancers.
科研貨號(hào)： PLA020915

PTF1A rabbit pAb

Catalog No PLA020915

Product information

基因名稱： PTF1A BHLHA29 PTF1P48
蛋白名稱： PTF1A
Human_gene_id： 256297
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=256297
Human_swiss_prot_no： Q7RTS3
Human_swiss_link： https://www.uniprot.org/uniprotkb/Q7RTS3/entry
Mouse_gene_id： 19213
Mouse_gene_link： https://www.uniprot.org/uniprot/19213
Mouse_swiss_prot_no： Q9QX98
Mouse_swiss_link： https://www.uniprot.org/uniprotkb/Q9QX98
Rat_gene_id： 117034
Rat_gene_link： https://www.uniprot.org/uniprot/117034
Rat_swiss_prot_no： Q64305
Rat_swiss_link： https://www.uniprot.org/uniprotkb/Q64305
特異性： This antibody detects endogenous levels of PTF1A at Human/Mouse/Rat
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來(lái)源： Polyclonal, Rabbit,IgG
稀釋： WB 1:500-2000;IHC-p 1:50-300
純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度： 1 mg/ml
儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
說(shuō)明書： 1
Msds： MSDS_Antibody.pdf
分子量： 36kD
功能： disease:Defects in PTF1A are the cause of diabetes mellitus and cerebellar hypoplasia/agenesis [MIM:609069].,function:Transcriptional activator. Binds to the E-box consensus sequence 5'-CANNTG-3'. Plays an important role in determining whether cells allocated to the pancreatic buds continue towards pancreatic organogenesis or revert back to duodenal fates. May be involved in the maintenance of exocrine pancreas-specific gene expression including ELA1 and amylase. Required for the formation of pancreatic acinar and ductal cells (By similarity). Plays an important role in cerebellar development.,miscellaneous:An excellent marker of acinar cell differentiation in the pancreas.,similarity:Contains 1 basic helix-loop-helix (bHLH) domain.,subcellular location:In chronic pancreatitis associated with pancreas cancer preferentially accumulates in the cytoplasm of acinar/ductular complexes. In the cytoplasm loses its ability to form the PTF1 complex.,subunit:Component of the pancreas transcription factor 1 complex (PTF1) which is composed of TCF3/p75, TCF12/p64 and PTF1A/p48. TCF3 is responsible for the nuclear import of the p48/p64 complex. Interacts with TCF3 and RBPSUH/RBP-Jkappa.,tissue specificity:Pancreas-specific (at protein level). Loss of expression is seen in ductal type pancreas cancers.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： Nucleus . Cytoplasm . In chronic pancreatitis associated with pancreas cancer preferentially accumulates in the cytoplasm of acinar/ductular complexes. In the cytoplasm loses its ability to form the PTF1 complex (By similarity). .
組織表達(dá)： Pancreas-specific (at protein level). Loss of expression is seen in ductal type pancreas cancers.
科研貨號(hào)： PLA020915

Hunan UPT Biotechnology Co.,Ltd

Website：m.tjdqdt.com Servive hotline :4006916686

E-mail：service@uptbio.com

Address：

Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.

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