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ENC1 rabbit pAb

商品貨號(hào)： PLA020861

適應(yīng) 性： 人,小鼠

￥600元

規(guī)格：

40μL 100μL 200μL

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MSDS

說明書

商品描述

基因名稱： ENC1 KLHL37 NRPB PIG10
蛋白名稱： ENC1
Human_gene_id： 8507
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=8507
Human_swiss_prot_no： O14682
Human_swiss_link： https://www.uniprot.org/uniprotkb/O14682/entry
Mouse_gene_id： 13803
Mouse_gene_link： https://www.uniprot.org/uniprot/13803
Mouse_swiss_prot_no： O35709
Mouse_swiss_link： https://www.uniprot.org/uniprotkb/O35709
特異性： This antibody detects endogenous levels of ENC1 at Human/Mouse
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來源： Polyclonal, Rabbit,IgG
稀釋： WB 1：500-2000
純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度： 1 mg/ml
儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
說明書： 1
Msds： MSDS_Antibody.pdf
分子量： 65kD
功能： developmental stage:Dramatically up-regulated upon neuronal differentiation.,function:Actin-binding protein involved in the regulation of neuronal process formation and in differentiation of neural crest cells. May be down-regulated in neuroblastoma tumors. Substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.,induction:By TP53/p53.,pathway:Protein modification; protein ubiquitination.,PTM:Phosphorylated.,PTM:Ubiquitinated and probably targeted for proteasome-independent degradation.,similarity:Contains 1 BTB (POZ) domain.,similarity:Contains 6 Kelch repeats.,subunit:Binds to RB1. Hypophosphorylated RB1 associates with ENC1 during neuronal differentiation, while hyperphosphorylated RB1 associates with ENC1 in undifferentiating cells. Part of a complex that contains CUL3, RBX1 and ENC1.,tissue specificity:Detected in fetal brain tissue, moderate expression in fetal heart, lung and kidney. Highly expressed in adult brain, particularly high in the hippocampus and amygdala, and spinal chord. Detectable in adult pancreas.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： Nucleus matrix . Cytoplasm . Cytoplasm, cytoskeleton .
組織表達(dá)： Detected in fetal brain tissue, moderate expression in fetal heart, lung and kidney. Highly expressed in adult brain, particularly high in the hippocampus and amygdala, and spinal chord. Detectable in adult pancreas. May be down-regulated in neuroblastoma tumors.
科研貨號(hào)： PLA020861

ENC1 rabbit pAb

Catalog No PLA020861

Product information

基因名稱： ENC1 KLHL37 NRPB PIG10
蛋白名稱： ENC1
Human_gene_id： 8507
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=8507
Human_swiss_prot_no： O14682
Human_swiss_link： https://www.uniprot.org/uniprotkb/O14682/entry
Mouse_gene_id： 13803
Mouse_gene_link： https://www.uniprot.org/uniprot/13803
Mouse_swiss_prot_no： O35709
Mouse_swiss_link： https://www.uniprot.org/uniprotkb/O35709
特異性： This antibody detects endogenous levels of ENC1 at Human/Mouse
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來源： Polyclonal, Rabbit,IgG
稀釋： WB 1：500-2000
純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度： 1 mg/ml
儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
說明書： 1
Msds： MSDS_Antibody.pdf
分子量： 65kD
功能： developmental stage:Dramatically up-regulated upon neuronal differentiation.,function:Actin-binding protein involved in the regulation of neuronal process formation and in differentiation of neural crest cells. May be down-regulated in neuroblastoma tumors. Substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.,induction:By TP53/p53.,pathway:Protein modification; protein ubiquitination.,PTM:Phosphorylated.,PTM:Ubiquitinated and probably targeted for proteasome-independent degradation.,similarity:Contains 1 BTB (POZ) domain.,similarity:Contains 6 Kelch repeats.,subunit:Binds to RB1. Hypophosphorylated RB1 associates with ENC1 during neuronal differentiation, while hyperphosphorylated RB1 associates with ENC1 in undifferentiating cells. Part of a complex that contains CUL3, RBX1 and ENC1.,tissue specificity:Detected in fetal brain tissue, moderate expression in fetal heart, lung and kidney. Highly expressed in adult brain, particularly high in the hippocampus and amygdala, and spinal chord. Detectable in adult pancreas.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： Nucleus matrix . Cytoplasm . Cytoplasm, cytoskeleton .
組織表達(dá)： Detected in fetal brain tissue, moderate expression in fetal heart, lung and kidney. Highly expressed in adult brain, particularly high in the hippocampus and amygdala, and spinal chord. Detectable in adult pancreas. May be down-regulated in neuroblastoma tumors.
科研貨號(hào)： PLA020861

Hunan UPT Biotechnology Co.,Ltd

Website：m.tjdqdt.com Servive hotline :4006916686

E-mail：service@uptbio.com

Address：

Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.

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