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DOLK rabbit pAb

商品貨號： PLA020732

適應(yīng) 性： 人,小鼠

￥600元

規(guī)格：

40μL 100μL 200μL

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MSDS

說明書

商品描述

基因名稱： DOLK KIAA1094 TMEM15 UNQ2422/PRO4980
蛋白名稱： DOLK
Human_gene_id： 22845
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=22845
Human_swiss_prot_no： Q9UPQ8
Human_swiss_link： https://www.uniprot.org/uniprotkb/Q9UPQ8/entry
Mouse_gene_id： 227697
Mouse_gene_link： https://www.uniprot.org/uniprot/227697
Mouse_swiss_prot_no： Q8R2Y3
Mouse_swiss_link： https://www.uniprot.org/uniprotkb/Q8R2Y3
特異性： This antibody detects endogenous levels of DOLK at Human/Mouse
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來源： Polyclonal, Rabbit,IgG
稀釋： WB 1：500-2000
純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度： 1 mg/ml
儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
說明書： 1
Msds： MSDS_Antibody.pdf
分子量： 59kD
功能： catalytic activity:CTP + dolichol = CDP + dolichyl phosphate.,disease:Defects in DOLK are the cause of congenital disorder of glycosylation type 1M (CDG1M) [MIM:610768]; also known as dolichol kinase deficiency. CDGs are a family of severe inherited diseases caused by a defect in glycoprotein biosynthesis. They are characterized by under-glycosylated serum glycoproteins. These multisystem disorders present with a wide variety of clinical features, such as disorders of the nervous system development, psychomotor retardation, dysmorphic features, hypotonia, coagulation disorders, and immunodeficiency. The broad spectrum of features reflects the critical role of N-glycoproteins during embryonic development, differentiation, and maintenance of cell functions. CDG1M is a very severe disorder with death occurring in early infancy.,function:Involved in the synthesis of the sugar donor Dol-P-Man which is required in the synthesis of N-linked and O-linked oligosaccharides and for that of GPI anchors.,miscellaneous:Complements the defects in growth, dolichol kinase activity and protein N-glycosylation at the restrictive temperature in yeast sec59 mutant cells.,similarity:Belongs to the polyprenol kinase family.,tissue specificity:Ubiquitous.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： Endoplasmic reticulum membrane ; Multi-pass membrane protein .
組織表達(dá)： Ubiquitous.
科研貨號： PLA020732

DOLK rabbit pAb

Catalog No PLA020732

Product information

基因名稱： DOLK KIAA1094 TMEM15 UNQ2422/PRO4980
蛋白名稱： DOLK
Human_gene_id： 22845
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=22845
Human_swiss_prot_no： Q9UPQ8
Human_swiss_link： https://www.uniprot.org/uniprotkb/Q9UPQ8/entry
Mouse_gene_id： 227697
Mouse_gene_link： https://www.uniprot.org/uniprot/227697
Mouse_swiss_prot_no： Q8R2Y3
Mouse_swiss_link： https://www.uniprot.org/uniprotkb/Q8R2Y3
特異性： This antibody detects endogenous levels of DOLK at Human/Mouse
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來源： Polyclonal, Rabbit,IgG
稀釋： WB 1：500-2000
純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度： 1 mg/ml
儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
說明書： 1
Msds： MSDS_Antibody.pdf
分子量： 59kD
功能： catalytic activity:CTP + dolichol = CDP + dolichyl phosphate.,disease:Defects in DOLK are the cause of congenital disorder of glycosylation type 1M (CDG1M) [MIM:610768]; also known as dolichol kinase deficiency. CDGs are a family of severe inherited diseases caused by a defect in glycoprotein biosynthesis. They are characterized by under-glycosylated serum glycoproteins. These multisystem disorders present with a wide variety of clinical features, such as disorders of the nervous system development, psychomotor retardation, dysmorphic features, hypotonia, coagulation disorders, and immunodeficiency. The broad spectrum of features reflects the critical role of N-glycoproteins during embryonic development, differentiation, and maintenance of cell functions. CDG1M is a very severe disorder with death occurring in early infancy.,function:Involved in the synthesis of the sugar donor Dol-P-Man which is required in the synthesis of N-linked and O-linked oligosaccharides and for that of GPI anchors.,miscellaneous:Complements the defects in growth, dolichol kinase activity and protein N-glycosylation at the restrictive temperature in yeast sec59 mutant cells.,similarity:Belongs to the polyprenol kinase family.,tissue specificity:Ubiquitous.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： Endoplasmic reticulum membrane ; Multi-pass membrane protein .
組織表達(dá)： Ubiquitous.
科研貨號： PLA020732

Hunan UPT Biotechnology Co.,Ltd

Website：m.tjdqdt.com Servive hotline :4006916686

E-mail：service@uptbio.com

Address：

Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.

亚洲国产日韩不卡综合,明星ai换脸磁力资源种子搜索,成人性闻CCAV下载,欧美日本国产在线a小说v,亚洲欧洲综合一区二区三区,里中结衣av中文字幕