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S27A1 rabbit pAb

商品貨號(hào)： PLA020679

適應(yīng) 性： 人,小鼠,大鼠

￥600元

規(guī)格：

40μL 100μL 200μL

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MSDS

說明書

商品描述

基因名稱： SLC27A1 ACSVL5 FATP1
蛋白名稱： S27A1
Human_gene_id： 376497
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=376497
Human_swiss_prot_no： Q6PCB7
Human_swiss_link： https://www.uniprot.org/uniprotkb/Q6PCB7/entry
Mouse_gene_id： 26457
Mouse_gene_link： https://www.uniprot.org/uniprot/26457
Mouse_swiss_prot_no： Q60714
Mouse_swiss_link： https://www.uniprot.org/uniprotkb/Q60714
Rat_swiss_prot_no： P97849
Rat_swiss_link： https://www.uniprot.org/uniprotkb/P97849
特異性： This antibody detects endogenous levels of S27A1 at Human/Mouse/Rat
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來源： Polyclonal, Rabbit,IgG
稀釋： WB 1：500-2000
純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度： 1 mg/ml
儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
說明書： 1
Msds： MSDS_Antibody.pdf
分子量： 71kD
功能： function:Involved in translocation of long-chain fatty acids (LFCA) across the plasma membrane. The LFCA import appears to be hormone-regulated in a tissue-specific manner. In adipocytes, but not myocytes, insulin induces a rapid translocation of Fatp1 from intracellular compartments to the plasma membrane, paralleled by increased LFCA uptake. May act directly as a bona fide transporter, or alternatively, in a cytoplasmic or membrane-associated multimeric protein complex to trap and draw fatty acids towards accumulation. Plays a pivotal role in regulating available LFCA substrates from exogenous sources in tissues undergoing high levels of beta-oxidation or triglyceride synthesis. May be involved in regulation of cholesterol metabolism. Has acyl-CoA ligase activity for long-chain and very-long-chain fatty acids.,miscellaneous:FATP1-mediated fatty acid uptake is associated to paramaters related to insulin resistance, which is associated with disturbed fatty acid metabolism and homeostasis, such as obesity.,similarity:Belongs to the ATP-dependent AMP-binding enzyme family.,subcellular location:Plasma membrane and intracellular membranes, at least in adipocytes. Predominantly cytoplasmic in myocytes.,subunit:Self-associates. May function as an homodimer.,tissue specificity:Highest levels of expression are detected in muscle and adipose tissue small, intermediate levels in small intestine, and barely detectable in liver.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： Cell membrane ; Single-pass membrane protein . Endomembrane system ; Single-pass membrane protein . Cytoplasm . Plasma membrane and intracellular membranes, at least in adipocytes. In adipocytes, but not myocytes, insulin via the mTORC1 signaling pathway induces a rapid translocation of SLC27A1 from intracellular compartments to the plasma membrane, paralleled by increased LCFA uptake. Insulin-dependent translocation from the cytoplasm to the cell membrane is regulated by EPRS1. Predominantly cytoplasmic in myocytes. .
組織表達(dá)： Highest levels of expression are detected in muscle and adipose tissue small, intermediate levels in small intestine, and barely detectable in liver. Expressed in brain gray matter (PubMed:21395585).
科研貨號(hào)： PLA020679

S27A1 rabbit pAb

Catalog No PLA020679

Product information

基因名稱： SLC27A1 ACSVL5 FATP1
蛋白名稱： S27A1
Human_gene_id： 376497
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=376497
Human_swiss_prot_no： Q6PCB7
Human_swiss_link： https://www.uniprot.org/uniprotkb/Q6PCB7/entry
Mouse_gene_id： 26457
Mouse_gene_link： https://www.uniprot.org/uniprot/26457
Mouse_swiss_prot_no： Q60714
Mouse_swiss_link： https://www.uniprot.org/uniprotkb/Q60714
Rat_swiss_prot_no： P97849
Rat_swiss_link： https://www.uniprot.org/uniprotkb/P97849
特異性： This antibody detects endogenous levels of S27A1 at Human/Mouse/Rat
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來源： Polyclonal, Rabbit,IgG
稀釋： WB 1：500-2000
純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度： 1 mg/ml
儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
說明書： 1
Msds： MSDS_Antibody.pdf
分子量： 71kD
功能： function:Involved in translocation of long-chain fatty acids (LFCA) across the plasma membrane. The LFCA import appears to be hormone-regulated in a tissue-specific manner. In adipocytes, but not myocytes, insulin induces a rapid translocation of Fatp1 from intracellular compartments to the plasma membrane, paralleled by increased LFCA uptake. May act directly as a bona fide transporter, or alternatively, in a cytoplasmic or membrane-associated multimeric protein complex to trap and draw fatty acids towards accumulation. Plays a pivotal role in regulating available LFCA substrates from exogenous sources in tissues undergoing high levels of beta-oxidation or triglyceride synthesis. May be involved in regulation of cholesterol metabolism. Has acyl-CoA ligase activity for long-chain and very-long-chain fatty acids.,miscellaneous:FATP1-mediated fatty acid uptake is associated to paramaters related to insulin resistance, which is associated with disturbed fatty acid metabolism and homeostasis, such as obesity.,similarity:Belongs to the ATP-dependent AMP-binding enzyme family.,subcellular location:Plasma membrane and intracellular membranes, at least in adipocytes. Predominantly cytoplasmic in myocytes.,subunit:Self-associates. May function as an homodimer.,tissue specificity:Highest levels of expression are detected in muscle and adipose tissue small, intermediate levels in small intestine, and barely detectable in liver.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： Cell membrane ; Single-pass membrane protein . Endomembrane system ; Single-pass membrane protein . Cytoplasm . Plasma membrane and intracellular membranes, at least in adipocytes. In adipocytes, but not myocytes, insulin via the mTORC1 signaling pathway induces a rapid translocation of SLC27A1 from intracellular compartments to the plasma membrane, paralleled by increased LCFA uptake. Insulin-dependent translocation from the cytoplasm to the cell membrane is regulated by EPRS1. Predominantly cytoplasmic in myocytes. .
組織表達(dá)： Highest levels of expression are detected in muscle and adipose tissue small, intermediate levels in small intestine, and barely detectable in liver. Expressed in brain gray matter (PubMed:21395585).
科研貨號(hào)： PLA020679

Hunan UPT Biotechnology Co.,Ltd

Website：m.tjdqdt.com Servive hotline :4006916686

E-mail：service@uptbio.com

Address：

Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.

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