功能: sequence caution:Translated as Trp.,similarity:Contains 2 FYVE-type zinc fingers.,subcellular location:Resides predominantly in the cisternal stacks of the Golgi.,subunit:Binds to phosphatidylinositol-3-phosphate (PtdIns3P) through its FYVE-type zinc finger.,tissue specificity:Isoform 1 was expressed in all tissues examined, including, brain, placenta, lung, liver, skeletal muscle, pancreas and kidney. Both isoforms, 1 and 2 showed a high expression in heart. Isoform 2 is also detected in the testis.,
相關(guān)產(chǎn)品: RS0001,RS0002,YM3028,YM3029
細(xì)胞定位: Golgi apparatus, Golgi stack . Golgi apparatus . Endoplasmic reticulum . Lipid droplet . Preautophagosomal structure . Mitochondrion . Resides predominantly in the cisternal stacks of the Golgi (PubMed:11256955). Colocalizes with TRIM13 on the perinuclear endoplasmic reticulum (PubMed:22178386). During starvation conditions, localizes to omegasomes which are endoplasmic reticulum connected strutures at the origin of preautophagosomal structures (PubMed:31293035, PubMed:25876663). Localizes to lipid droplets in the presence of oleic acid (PubMed:31293035, PubMed:30970241). .
組織表達(dá): [Isoform 2]: Highly expressed in heart. Also detected in the testis. ; [Isoform 1]: Expressed in all tissues examined, including, brain, placenta, lung, liver, skeletal muscle, pancreas and kidney. Highly expressed in heart.
功能: sequence caution:Translated as Trp.,similarity:Contains 2 FYVE-type zinc fingers.,subcellular location:Resides predominantly in the cisternal stacks of the Golgi.,subunit:Binds to phosphatidylinositol-3-phosphate (PtdIns3P) through its FYVE-type zinc finger.,tissue specificity:Isoform 1 was expressed in all tissues examined, including, brain, placenta, lung, liver, skeletal muscle, pancreas and kidney. Both isoforms, 1 and 2 showed a high expression in heart. Isoform 2 is also detected in the testis.,
相關(guān)產(chǎn)品: RS0001,RS0002,YM3028,YM3029
細(xì)胞定位: Golgi apparatus, Golgi stack . Golgi apparatus . Endoplasmic reticulum . Lipid droplet . Preautophagosomal structure . Mitochondrion . Resides predominantly in the cisternal stacks of the Golgi (PubMed:11256955). Colocalizes with TRIM13 on the perinuclear endoplasmic reticulum (PubMed:22178386). During starvation conditions, localizes to omegasomes which are endoplasmic reticulum connected strutures at the origin of preautophagosomal structures (PubMed:31293035, PubMed:25876663). Localizes to lipid droplets in the presence of oleic acid (PubMed:31293035, PubMed:30970241). .
組織表達(dá): [Isoform 2]: Highly expressed in heart. Also detected in the testis. ; [Isoform 1]: Expressed in all tissues examined, including, brain, placenta, lung, liver, skeletal muscle, pancreas and kidney. Highly expressed in heart.
科研貨號(hào): PLA020631
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