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ZN423 rabbit pAb

商品貨號(hào)： PLA020474

適應(yīng) 性： 人,小鼠,大鼠

￥600元

規(guī)格：

40μL 100μL 200μL

在線咨詢(xún)

MSDS

說(shuō)明書(shū)

商品描述

基因名稱(chēng)： ZNF423 KIAA0760 NPHP14 OAZ
蛋白名稱(chēng)： ZN423
Human_gene_id： 23090
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=23090
Human_swiss_prot_no： Q2M1K9
Human_swiss_link： https://www.uniprot.org/uniprotkb/Q2M1K9/entry
Mouse_gene_id： 94187
Mouse_gene_link： https://www.uniprot.org/uniprot/94187
Mouse_swiss_prot_no： Q80TS5
Mouse_swiss_link： https://www.uniprot.org/uniprotkb/Q80TS5
Rat_gene_id： 94188
Rat_gene_link： https://www.uniprot.org/uniprot/94188
Rat_swiss_prot_no： O08961
Rat_swiss_link： https://www.uniprot.org/uniprotkb/O08961
特異性： This antibody detects endogenous levels of ZN423 at Human/Mouse/Rat
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來(lái)源： Polyclonal, Rabbit,IgG
稀釋?zhuān)? WB 1：500-2000
純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度： 1 mg/ml
儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
說(shuō)明書(shū)： 1
Msds： MSDS_Antibody.pdf
分子量： 141kD
功能： domain:Uses different DNA- and protein-binding zinc fingers to regulate the distinct BMP-Smad and Olf signaling pathways. C2H2-type zinc fingers 14-19 mediate the interaction with SMAD1 and SMAD4, while zinc fingers 28-30 mediate the interaction with EBF1. zinc fingers 2-8 bind the 5'-CCGCCC-3' DNA sequence in concert with EBF1, while zinc fingers 9-13 bind BMP target gene promoters in concert with SMADs.,function:Transcription factor that can both act as an activator or a repressor depending on the context. Plays a central role in BMP signaling and olfactory neurogenesis. Associates with SMADs in response to BMP2 leading to activate transcription of BMP target genes. Acts as a transcriptional repressor via its interaction with EBF1, a transcription factor involved in terminal olfactory receptor neurons differentiation; this interaction preventing EBF1 to bind DNA and activate olfactory-specific genes. Involved in olfactory neurogenesis by participating in a developmental switch that regulates the transition from differentiation to maturation in olfactory receptor neurons. Controls proliferation and differentiation of neural precursors in cerebellar vermis formation.,similarity:Belongs to the krueppel C2H2-type zinc-finger protein family.,similarity:Contains 30 C2H2-type zinc fingers.,subunit:Homodimer (By similarity). Interacts with PARP1 and EBF1 (By similarity). Interacts with SMAD1 and SMAD4.,tissue specificity:Expressed in brain, lung, skeletal muscle, heart, pancreas and kidney but not liver or placenta. Also expressed in aorta, ovary, pituitary, small intestine, fetal brain, fetal kidney and, within the adult brain, in the substantia nigra, medulla, amygdala, thalamus and cerebellum.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： Nucleus .
組織表達(dá)： Expressed in brain, lung, skeletal muscle, heart, pancreas and kidney but not liver or placenta. Also expressed in aorta, ovary, pituitary, small intestine, fetal brain, fetal kidney and, within the adult brain, in the substantia nigra, medulla, amygdala, thalamus and cerebellum.
科研貨號(hào)： PLA020474

ZN423 rabbit pAb

Catalog No PLA020474

Product information

基因名稱(chēng)： ZNF423 KIAA0760 NPHP14 OAZ
蛋白名稱(chēng)： ZN423
Human_gene_id： 23090
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=23090
Human_swiss_prot_no： Q2M1K9
Human_swiss_link： https://www.uniprot.org/uniprotkb/Q2M1K9/entry
Mouse_gene_id： 94187
Mouse_gene_link： https://www.uniprot.org/uniprot/94187
Mouse_swiss_prot_no： Q80TS5
Mouse_swiss_link： https://www.uniprot.org/uniprotkb/Q80TS5
Rat_gene_id： 94188
Rat_gene_link： https://www.uniprot.org/uniprot/94188
Rat_swiss_prot_no： O08961
Rat_swiss_link： https://www.uniprot.org/uniprotkb/O08961
特異性： This antibody detects endogenous levels of ZN423 at Human/Mouse/Rat
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來(lái)源： Polyclonal, Rabbit,IgG
稀釋?zhuān)? WB 1：500-2000
純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度： 1 mg/ml
儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
說(shuō)明書(shū)： 1
Msds： MSDS_Antibody.pdf
分子量： 141kD
功能： domain:Uses different DNA- and protein-binding zinc fingers to regulate the distinct BMP-Smad and Olf signaling pathways. C2H2-type zinc fingers 14-19 mediate the interaction with SMAD1 and SMAD4, while zinc fingers 28-30 mediate the interaction with EBF1. zinc fingers 2-8 bind the 5'-CCGCCC-3' DNA sequence in concert with EBF1, while zinc fingers 9-13 bind BMP target gene promoters in concert with SMADs.,function:Transcription factor that can both act as an activator or a repressor depending on the context. Plays a central role in BMP signaling and olfactory neurogenesis. Associates with SMADs in response to BMP2 leading to activate transcription of BMP target genes. Acts as a transcriptional repressor via its interaction with EBF1, a transcription factor involved in terminal olfactory receptor neurons differentiation; this interaction preventing EBF1 to bind DNA and activate olfactory-specific genes. Involved in olfactory neurogenesis by participating in a developmental switch that regulates the transition from differentiation to maturation in olfactory receptor neurons. Controls proliferation and differentiation of neural precursors in cerebellar vermis formation.,similarity:Belongs to the krueppel C2H2-type zinc-finger protein family.,similarity:Contains 30 C2H2-type zinc fingers.,subunit:Homodimer (By similarity). Interacts with PARP1 and EBF1 (By similarity). Interacts with SMAD1 and SMAD4.,tissue specificity:Expressed in brain, lung, skeletal muscle, heart, pancreas and kidney but not liver or placenta. Also expressed in aorta, ovary, pituitary, small intestine, fetal brain, fetal kidney and, within the adult brain, in the substantia nigra, medulla, amygdala, thalamus and cerebellum.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： Nucleus .
組織表達(dá)： Expressed in brain, lung, skeletal muscle, heart, pancreas and kidney but not liver or placenta. Also expressed in aorta, ovary, pituitary, small intestine, fetal brain, fetal kidney and, within the adult brain, in the substantia nigra, medulla, amygdala, thalamus and cerebellum.
科研貨號(hào)： PLA020474

Hunan UPT Biotechnology Co.,Ltd

Website：m.tjdqdt.com Servive hotline :4006916686

E-mail：service@uptbio.com

Address：

Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.

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