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CRBB1 rabbit pAb

商品貨號(hào)： PLA020460

適應(yīng) 性： 人,小鼠,大鼠

￥600元

規(guī)格：

40μL 100μL 200μL

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MSDS

說明書

商品描述

基因名稱： CRYBB1
蛋白名稱： CRBB1
Human_gene_id： 1414
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=1414
Human_swiss_prot_no： P53674
Human_swiss_link： https://www.uniprot.org/uniprotkb/P53674/entry
Mouse_gene_id： 12960
Mouse_gene_link： https://www.uniprot.org/uniprot/12960
Mouse_swiss_prot_no： Q9WVJ5
Mouse_swiss_link： https://www.uniprot.org/uniprotkb/Q9WVJ5
Rat_gene_id： 25421
Rat_gene_link： https://www.uniprot.org/uniprot/25421
Rat_swiss_prot_no： P02523
Rat_swiss_link： https://www.uniprot.org/uniprotkb/P02523
特異性： This antibody detects endogenous levels of CRBB1 at Human/Mouse/Rat
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來源： Polyclonal, Rabbit,IgG
稀釋： WB 1：500-2000
純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度： 1 mg/ml
儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
說明書： 1
Msds： MSDS_Antibody.pdf
分子量： 28kD
功能： disease:Defects in CRYBB1 are the cause of autosomal recessive congenital nuclear cataract type 3 (CATCN3) [MIM:611544]. CATCN3 is a form of non-syndromic congenital cataract. Non-syndromic congenital cataracts vary markedly in severity and morphology, affecting the nuclear, cortical, polar, or subcapsular parts of the lens or, in severe cases, the entire lens, with a variety of types of opacity. They are one of the major causes of vision loss in children worldwide and are responsible for approximately one third of blindness in infants. Congenital cataracts can lead to permanent blindness by interfering with the sharp focus of light on the retina during critical developmental intervals.,domain:Has a two-domain beta-structure, folded into four very similar Greek key motifs.,function:Crystallins are the dominant structural components of the vertebrate eye lens.,mass spectrometry: PubMed:8626774,PTM:Specific cleavages in the N-terminal arm occur during lens maturation and give rise to truncated forms, leading to impaired oligomerization and protein insolubilization.,similarity:Belongs to the beta/gamma-crystallin family.,similarity:Contains 4 beta/gamma crystallin 'Greek key' domains.,subunit:Homo/heterodimer, or complexes of higher order. The structure of beta-crystallin oligomers seems to be stabilized through interactions between the N-terminal arms.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
科研貨號(hào)： PLA020460

CRBB1 rabbit pAb

Catalog No PLA020460

Product information

基因名稱： CRYBB1
蛋白名稱： CRBB1
Human_gene_id： 1414
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=1414
Human_swiss_prot_no： P53674
Human_swiss_link： https://www.uniprot.org/uniprotkb/P53674/entry
Mouse_gene_id： 12960
Mouse_gene_link： https://www.uniprot.org/uniprot/12960
Mouse_swiss_prot_no： Q9WVJ5
Mouse_swiss_link： https://www.uniprot.org/uniprotkb/Q9WVJ5
Rat_gene_id： 25421
Rat_gene_link： https://www.uniprot.org/uniprot/25421
Rat_swiss_prot_no： P02523
Rat_swiss_link： https://www.uniprot.org/uniprotkb/P02523
特異性： This antibody detects endogenous levels of CRBB1 at Human/Mouse/Rat
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來源： Polyclonal, Rabbit,IgG
稀釋： WB 1：500-2000
純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度： 1 mg/ml
儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
說明書： 1
Msds： MSDS_Antibody.pdf
分子量： 28kD
功能： disease:Defects in CRYBB1 are the cause of autosomal recessive congenital nuclear cataract type 3 (CATCN3) [MIM:611544]. CATCN3 is a form of non-syndromic congenital cataract. Non-syndromic congenital cataracts vary markedly in severity and morphology, affecting the nuclear, cortical, polar, or subcapsular parts of the lens or, in severe cases, the entire lens, with a variety of types of opacity. They are one of the major causes of vision loss in children worldwide and are responsible for approximately one third of blindness in infants. Congenital cataracts can lead to permanent blindness by interfering with the sharp focus of light on the retina during critical developmental intervals.,domain:Has a two-domain beta-structure, folded into four very similar Greek key motifs.,function:Crystallins are the dominant structural components of the vertebrate eye lens.,mass spectrometry: PubMed:8626774,PTM:Specific cleavages in the N-terminal arm occur during lens maturation and give rise to truncated forms, leading to impaired oligomerization and protein insolubilization.,similarity:Belongs to the beta/gamma-crystallin family.,similarity:Contains 4 beta/gamma crystallin 'Greek key' domains.,subunit:Homo/heterodimer, or complexes of higher order. The structure of beta-crystallin oligomers seems to be stabilized through interactions between the N-terminal arms.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
科研貨號(hào)： PLA020460

Hunan UPT Biotechnology Co.,Ltd

Website：m.tjdqdt.com Servive hotline :4006916686

E-mail：service@uptbio.com

Address：

Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.

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