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UBA3 rabbit pAb

商品貨號： PLA020396

適應(yīng) 性： 人,小鼠,大鼠

￥600元

規(guī)格：

40μL 100μL 200μL

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MSDS

說明書

商品描述

基因名稱： UBA3 UBE1C
蛋白名稱： UBA3
Human_gene_id： 9039
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=9039
Human_swiss_prot_no： Q8TBC4
Human_swiss_link： https://www.uniprot.org/uniprotkb/Q8TBC4/entry
Mouse_gene_id： 22200
Mouse_gene_link： https://www.uniprot.org/uniprot/22200
Mouse_swiss_prot_no： Q8C878
Mouse_swiss_link： https://www.uniprot.org/uniprotkb/Q8C878
Rat_gene_id： 117553
Rat_gene_link： https://www.uniprot.org/uniprot/117553
Rat_swiss_prot_no： Q99MI7
Rat_swiss_link： https://www.uniprot.org/uniprotkb/Q99MI7
特異性： This antibody detects endogenous levels of UBA3 at Human/Mouse/Rat
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來源： Polyclonal, Rabbit,IgG
稀釋： WB 1：500-2000
純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度： 1 mg/ml
儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
說明書： 1
Msds： MSDS_Antibody.pdf
分子量： 51kD
功能： enzyme regulation:Binding of TP53BP2 to the regulatory subunit NAE1 decreases activity.,function:Catalytic subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Down-regulates steroid receptor activity. Necessary for cell cycle progression.,miscellaneous:Arg-211 acts as a selectivity gate, preventing misactivation of ubiquitin by this NEDD8-specific E1 complex.,pathway:Protein modification; protein neddylation.,similarity:Belongs to the ubiquitin-activating E1 family. UBA3 subfamily.,subunit:Heterodimer of UBA3 and NAE1. Interacts with NEDD8, UBE2F and UBE2M. Binds ESR1 and ESR2 with bound steroid ligand.,tissue specificity:Ubiquitously expressed.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： nucleus,cytosol,
組織表達(dá)： Ubiquitously expressed.
科研貨號： PLA020396

UBA3 rabbit pAb

Catalog No PLA020396

Product information

基因名稱： UBA3 UBE1C
蛋白名稱： UBA3
Human_gene_id： 9039
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=9039
Human_swiss_prot_no： Q8TBC4
Human_swiss_link： https://www.uniprot.org/uniprotkb/Q8TBC4/entry
Mouse_gene_id： 22200
Mouse_gene_link： https://www.uniprot.org/uniprot/22200
Mouse_swiss_prot_no： Q8C878
Mouse_swiss_link： https://www.uniprot.org/uniprotkb/Q8C878
Rat_gene_id： 117553
Rat_gene_link： https://www.uniprot.org/uniprot/117553
Rat_swiss_prot_no： Q99MI7
Rat_swiss_link： https://www.uniprot.org/uniprotkb/Q99MI7
特異性： This antibody detects endogenous levels of UBA3 at Human/Mouse/Rat
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來源： Polyclonal, Rabbit,IgG
稀釋： WB 1：500-2000
純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度： 1 mg/ml
儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
說明書： 1
Msds： MSDS_Antibody.pdf
分子量： 51kD
功能： enzyme regulation:Binding of TP53BP2 to the regulatory subunit NAE1 decreases activity.,function:Catalytic subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Down-regulates steroid receptor activity. Necessary for cell cycle progression.,miscellaneous:Arg-211 acts as a selectivity gate, preventing misactivation of ubiquitin by this NEDD8-specific E1 complex.,pathway:Protein modification; protein neddylation.,similarity:Belongs to the ubiquitin-activating E1 family. UBA3 subfamily.,subunit:Heterodimer of UBA3 and NAE1. Interacts with NEDD8, UBE2F and UBE2M. Binds ESR1 and ESR2 with bound steroid ligand.,tissue specificity:Ubiquitously expressed.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： nucleus,cytosol,
組織表達(dá)： Ubiquitously expressed.
科研貨號： PLA020396

Hunan UPT Biotechnology Co.,Ltd

Website：m.tjdqdt.com Servive hotline :4006916686

E-mail：service@uptbio.com

Address：

Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.

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