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SMS1 rabbit pAb

商品貨號： PLA020300

適應(yīng) 性： 人,小鼠,大鼠

￥600元

規(guī)格：

40μL 100μL 200μL

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MSDS

說明書

商品描述

基因名稱： SGMS1 MOB SMS1 TMEM23
蛋白名稱： SMS1
Human_gene_id： 259230
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=259230
Human_swiss_prot_no： Q86VZ5
Human_swiss_link： https://www.uniprot.org/uniprotkb/Q86VZ5/entry
Mouse_gene_id： 208449
Mouse_gene_link： https://www.uniprot.org/uniprot/208449
Mouse_swiss_prot_no： Q8VCQ6
Mouse_swiss_link： https://www.uniprot.org/uniprotkb/Q8VCQ6
Rat_gene_id： 353229
Rat_gene_link： https://www.uniprot.org/uniprot/353229
Rat_swiss_prot_no： Q7TSX5
Rat_swiss_link： https://www.uniprot.org/uniprotkb/Q7TSX5
特異性： This antibody detects endogenous levels of SMS1 at Human/Mouse/Rat
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來源： Polyclonal, Rabbit,IgG
稀釋： WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度： 1 mg/ml
儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
說明書： 1
Msds： MSDS_Antibody.pdf
分子量： 46kD
功能： catalytic activity:A ceramide + a phosphatidylcholine = a sphingomyelin + a 1,2-diacyl-sn-glycerol.,enzyme regulation:Inhibited by bacterial PC-phospholipase C inhibitor D609.,function:Bidirectional lipid cholinephosphotransferase capable of converting phosphatidylcholine (PC) and ceramide to sphingomyelin (SM) and diacylglycerol (DAG) and vice versa. Direction is dependent on the relative concentrations of DAG and ceramide as phosphocholine acceptors. Directly and specifically recognizes the choline head group on the substrate. Also requires two fatty chains on the choline-P donor molecule in order to be recognized efficiently as a substrate. Does not function strictly as a SM synthase. Suppresses BAX-mediated apoptosis and also prevents cell death in response to stimuli such as hydrogen peroxide, osmotic stress, elevated temperature and exogenously supplied sphingolipids. May protect against cell death by reversing the stress-inducible increase in levels of proapoptotic ceramide. Required for cell growth.,miscellaneous:Overexpression of the human protein in mouse causes increased non-HDL-sphingomyelin and non-HDL cholesterol levels, decreased HDL-sphingomyelin and HDL-cholesterol levels and increases lipoprotein atherogenic potential.,sequence caution:Unusual initiator. The initiator methionine is coded by a non-canonical CTG leucine codon.,similarity:Belongs to the sphingomyelin synthase family.,similarity:Contains 1 SAM (sterile alpha motif) domain.,tissue specificity:Brain, heart, kidney, liver, muscle and stomach.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： Golgi apparatus membrane ; Multi-pass membrane protein .
組織表達(dá)： Brain, heart, kidney, liver, muscle and stomach.
科研貨號： PLA020300

SMS1 rabbit pAb

Catalog No PLA020300

Product information

基因名稱： SGMS1 MOB SMS1 TMEM23
蛋白名稱： SMS1
Human_gene_id： 259230
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=259230
Human_swiss_prot_no： Q86VZ5
Human_swiss_link： https://www.uniprot.org/uniprotkb/Q86VZ5/entry
Mouse_gene_id： 208449
Mouse_gene_link： https://www.uniprot.org/uniprot/208449
Mouse_swiss_prot_no： Q8VCQ6
Mouse_swiss_link： https://www.uniprot.org/uniprotkb/Q8VCQ6
Rat_gene_id： 353229
Rat_gene_link： https://www.uniprot.org/uniprot/353229
Rat_swiss_prot_no： Q7TSX5
Rat_swiss_link： https://www.uniprot.org/uniprotkb/Q7TSX5
特異性： This antibody detects endogenous levels of SMS1 at Human/Mouse/Rat
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來源： Polyclonal, Rabbit,IgG
稀釋： WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度： 1 mg/ml
儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
說明書： 1
Msds： MSDS_Antibody.pdf
分子量： 46kD
功能： catalytic activity:A ceramide + a phosphatidylcholine = a sphingomyelin + a 1,2-diacyl-sn-glycerol.,enzyme regulation:Inhibited by bacterial PC-phospholipase C inhibitor D609.,function:Bidirectional lipid cholinephosphotransferase capable of converting phosphatidylcholine (PC) and ceramide to sphingomyelin (SM) and diacylglycerol (DAG) and vice versa. Direction is dependent on the relative concentrations of DAG and ceramide as phosphocholine acceptors. Directly and specifically recognizes the choline head group on the substrate. Also requires two fatty chains on the choline-P donor molecule in order to be recognized efficiently as a substrate. Does not function strictly as a SM synthase. Suppresses BAX-mediated apoptosis and also prevents cell death in response to stimuli such as hydrogen peroxide, osmotic stress, elevated temperature and exogenously supplied sphingolipids. May protect against cell death by reversing the stress-inducible increase in levels of proapoptotic ceramide. Required for cell growth.,miscellaneous:Overexpression of the human protein in mouse causes increased non-HDL-sphingomyelin and non-HDL cholesterol levels, decreased HDL-sphingomyelin and HDL-cholesterol levels and increases lipoprotein atherogenic potential.,sequence caution:Unusual initiator. The initiator methionine is coded by a non-canonical CTG leucine codon.,similarity:Belongs to the sphingomyelin synthase family.,similarity:Contains 1 SAM (sterile alpha motif) domain.,tissue specificity:Brain, heart, kidney, liver, muscle and stomach.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： Golgi apparatus membrane ; Multi-pass membrane protein .
組織表達(dá)： Brain, heart, kidney, liver, muscle and stomach.
科研貨號： PLA020300

Hunan UPT Biotechnology Co.,Ltd

Website：m.tjdqdt.com Servive hotline :4006916686

E-mail：service@uptbio.com

Address：

Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.

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