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IMDH1 rabbit pAb

商品貨號： PLA020293

適應(yīng) 性： 人,小鼠,大鼠

￥600元

規(guī)格：

40μL 100μL 200μL

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MSDS

說明書

商品描述

基因名稱： IMPDH1 IMPD1
蛋白名稱： IMDH1
Human_gene_id： 3614
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=3614
Human_swiss_prot_no： P20839
Human_swiss_link： https://www.uniprot.org/uniprotkb/P20839/entry
Mouse_gene_id： 23917
Mouse_gene_link： https://www.uniprot.org/uniprot/23917
Mouse_swiss_prot_no： P50096
Mouse_swiss_link： https://www.uniprot.org/uniprotkb/P50096
Rat_swiss_prot_no： D3ZLZ7
Rat_swiss_link： https://www.uniprot.org/uniprotkb/D3ZLZ7
特異性： This antibody detects endogenous levels of IMDH1 at Human/Mouse/Rat
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來源： Polyclonal, Rabbit,IgG
稀釋： WB 1：500-2000
純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度： 1 mg/ml
儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
說明書： 1
Msds： MSDS_Antibody.pdf
分子量： 57kD
功能： catalytic activity:Inosine 5'-phosphate + NAD(+) + H(2)O = xanthosine 5'-phosphate + NADH.,cofactor:Potassium.,disease:Defects in IMPDH1 are the cause of retinitis pigmentosa type 10 (RP10) [MIM:180105]. RP leads to degeneration of retinal photoreceptor cells. Patients typically have night vision blindness and loss of midperipheral visual field. As their condition progresses, they lose their far peripheral visual field and eventually central vision as well. RP10 inheritance is autosomal dominant.,function:Rate limiting enzyme in the de novo synthesis of guanine nucleotides and therefore is involved in the regulation of cell growth. It may also have a role in the development of malignancy and the growth progression of some tumors.,online information:Retina International's Scientific Newsletter,pathway:Purine metabolism; XMP biosynthesis via de novo pathway; XMP from IMP: step 1/1.,similarity:Belongs to the IMPDH/GMPR family.,similarity:Contains 2 CBS domains.,subunit:Homotetramer.,tissue specificity:IMP type I is the main species in normal leukocytes and type II predominates over type I in the tumor.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： Cytoplasm . Nucleus .
組織表達(dá)： IMP type I is the main species in normal leukocytes and type II predominates over type I in the tumor.
科研貨號： PLA020293

IMDH1 rabbit pAb

Catalog No PLA020293

Product information

基因名稱： IMPDH1 IMPD1
蛋白名稱： IMDH1
Human_gene_id： 3614
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=3614
Human_swiss_prot_no： P20839
Human_swiss_link： https://www.uniprot.org/uniprotkb/P20839/entry
Mouse_gene_id： 23917
Mouse_gene_link： https://www.uniprot.org/uniprot/23917
Mouse_swiss_prot_no： P50096
Mouse_swiss_link： https://www.uniprot.org/uniprotkb/P50096
Rat_swiss_prot_no： D3ZLZ7
Rat_swiss_link： https://www.uniprot.org/uniprotkb/D3ZLZ7
特異性： This antibody detects endogenous levels of IMDH1 at Human/Mouse/Rat
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來源： Polyclonal, Rabbit,IgG
稀釋： WB 1：500-2000
純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度： 1 mg/ml
儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
說明書： 1
Msds： MSDS_Antibody.pdf
分子量： 57kD
功能： catalytic activity:Inosine 5'-phosphate + NAD(+) + H(2)O = xanthosine 5'-phosphate + NADH.,cofactor:Potassium.,disease:Defects in IMPDH1 are the cause of retinitis pigmentosa type 10 (RP10) [MIM:180105]. RP leads to degeneration of retinal photoreceptor cells. Patients typically have night vision blindness and loss of midperipheral visual field. As their condition progresses, they lose their far peripheral visual field and eventually central vision as well. RP10 inheritance is autosomal dominant.,function:Rate limiting enzyme in the de novo synthesis of guanine nucleotides and therefore is involved in the regulation of cell growth. It may also have a role in the development of malignancy and the growth progression of some tumors.,online information:Retina International's Scientific Newsletter,pathway:Purine metabolism; XMP biosynthesis via de novo pathway; XMP from IMP: step 1/1.,similarity:Belongs to the IMPDH/GMPR family.,similarity:Contains 2 CBS domains.,subunit:Homotetramer.,tissue specificity:IMP type I is the main species in normal leukocytes and type II predominates over type I in the tumor.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： Cytoplasm . Nucleus .
組織表達(dá)： IMP type I is the main species in normal leukocytes and type II predominates over type I in the tumor.
科研貨號： PLA020293

Hunan UPT Biotechnology Co.,Ltd

Website：m.tjdqdt.com Servive hotline :4006916686

E-mail：service@uptbio.com

Address：

Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.

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