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MBD2 rabbit pAb

商品貨號： PLA020259

適應(yīng) 性： 人,小鼠

￥600元

規(guī)格：

40μL 100μL 200μL

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MSDS

說明書

商品描述

基因名稱： MBD2
蛋白名稱： MBD2
Human_gene_id： 8932
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=8932
Human_swiss_prot_no： Q9UBB5
Human_swiss_link： https://www.uniprot.org/uniprotkb/Q9UBB5/entry
Mouse_gene_id： 17191
Mouse_gene_link： https://www.uniprot.org/uniprot/17191
Mouse_swiss_prot_no： Q9Z2E1
Mouse_swiss_link： https://www.uniprot.org/uniprotkb/Q9Z2E1
特異性： This antibody detects endogenous levels of MBD2 at Human/Mouse
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來源： Polyclonal, Rabbit,IgG
稀釋： WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度： 1 mg/ml
儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
說明書： 1
Msds： MSDS_Antibody.pdf
分子量： 45kD
功能： function:Binds CpG islands in promoters where the DNA is methylated at position 5 of cytosine within CpG dinucleotides. Binds hemi-methylated DNA as well. Recruits histone deacetylases and DNA methyltransferases. Acts as transcriptional repressor and plays a role in gene silencing. Isoform 1 may enhance the activation of some unmethylated cAMP-responsive promoters. Reports about DNA demethylase activity of isoform 2 are contradictory.,similarity:Contains 1 MBD (methyl-CpG-binding) domain.,subcellular location:Nuclear, in discrete foci. Detected at replication foci in late S phase.,subunit:Heterodimer with MBD3. Part of the MeCP1 complex that contains HDAC1 and HDAC2. Binds DNMT1, MIZF, XAB1, SIN3A, p66-alpha and p66-beta. Isoform 1 binds DHX9, but isoform 2 does not.,tissue specificity:Highly expressed in brain, heart, kidney, stomach, testis and placenta.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： Nucleus . Nuclear, in discrete foci. Detected at replication foci in late S phase.
組織表達(dá)： Highly expressed in brain, heart, kidney, stomach, testis and placenta.
科研貨號： PLA020259

MBD2 rabbit pAb

Catalog No PLA020259

Product information

基因名稱： MBD2
蛋白名稱： MBD2
Human_gene_id： 8932
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=8932
Human_swiss_prot_no： Q9UBB5
Human_swiss_link： https://www.uniprot.org/uniprotkb/Q9UBB5/entry
Mouse_gene_id： 17191
Mouse_gene_link： https://www.uniprot.org/uniprot/17191
Mouse_swiss_prot_no： Q9Z2E1
Mouse_swiss_link： https://www.uniprot.org/uniprotkb/Q9Z2E1
特異性： This antibody detects endogenous levels of MBD2 at Human/Mouse
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來源： Polyclonal, Rabbit,IgG
稀釋： WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度： 1 mg/ml
儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
說明書： 1
Msds： MSDS_Antibody.pdf
分子量： 45kD
功能： function:Binds CpG islands in promoters where the DNA is methylated at position 5 of cytosine within CpG dinucleotides. Binds hemi-methylated DNA as well. Recruits histone deacetylases and DNA methyltransferases. Acts as transcriptional repressor and plays a role in gene silencing. Isoform 1 may enhance the activation of some unmethylated cAMP-responsive promoters. Reports about DNA demethylase activity of isoform 2 are contradictory.,similarity:Contains 1 MBD (methyl-CpG-binding) domain.,subcellular location:Nuclear, in discrete foci. Detected at replication foci in late S phase.,subunit:Heterodimer with MBD3. Part of the MeCP1 complex that contains HDAC1 and HDAC2. Binds DNMT1, MIZF, XAB1, SIN3A, p66-alpha and p66-beta. Isoform 1 binds DHX9, but isoform 2 does not.,tissue specificity:Highly expressed in brain, heart, kidney, stomach, testis and placenta.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： Nucleus . Nuclear, in discrete foci. Detected at replication foci in late S phase.
組織表達(dá)： Highly expressed in brain, heart, kidney, stomach, testis and placenta.
科研貨號： PLA020259

Hunan UPT Biotechnology Co.,Ltd

Website：m.tjdqdt.com Servive hotline :4006916686

E-mail：service@uptbio.com

Address：

Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.

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