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LCAT rabbit pAb

商品貨號： PLA020240

適應(yīng) 性： 人,小鼠,大鼠

￥600元

規(guī)格：

40μL 100μL 200μL

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MSDS

說明書

商品描述

基因名稱： LCAT
蛋白名稱： LCAT
Human_gene_id： 3931
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=3931
Human_swiss_prot_no： P04180
Human_swiss_link： https://www.uniprot.org/uniprotkb/P04180/entry
Mouse_gene_id： 16816
Mouse_gene_link： https://www.uniprot.org/uniprot/16816
Mouse_swiss_prot_no： P16301
Mouse_swiss_link： https://www.uniprot.org/uniprotkb/P16301
Rat_swiss_prot_no： P18424
Rat_swiss_link： https://www.uniprot.org/uniprotkb/P18424
特異性： This antibody detects endogenous levels of LCAT at Human/Mouse/Rat
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來源： Polyclonal, Rabbit,IgG
稀釋： WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度： 1 mg/ml
儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
說明書： 1
Msds： MSDS_Antibody.pdf
分子量： 48kD
功能： catalytic activity:Phosphatidylcholine + a sterol = 1-acylglycerophosphocholine + a sterol ester.,disease:Defects in LCAT are a cause of fish-eye disease (FED) [MIM:136120]; also known as dyslipoproteinemic corneal dystrophy or alpha-LCAT deficiency. FED is due to a partial LCAT deficiency that affects only alpha-LCAT activity. It is characterized by low plasma HDL and corneal opacities due to accumulation of cholesterol deposits in the cornea ('fish-eye').,disease:Defects in LCAT are the cause of lecithin-cholesterol acyltransferase deficiency (LCATD) [MIM:245900]; also called Norum disease. LCATD is a disorder of lipoprotein metabolism characterized by inadequate esterification of plasmatic cholesterol. Two clinical forms are recognized: familial LCAT deficiency and fish-eye disease. Familial LCAT deficiency is associated with a complete absence of alpha and beta LCAT activities and results in esterification anomalies involving both HDL (alpha-LCAT activity) and LDL (beta-LCAT activity). It causes a typical triad of diffuse corneal opacities, target cell hemolytic anemia, and proteinuria with renal failure.,enzyme regulation:Apolipoprotein A-I is a potent activator for this enzyme.,function:Central enzyme in the extracellular metabolism of plasma lipoproteins. Among other substrates it esterifies the free cholesterol transported in plasma lipoproteins.,online information:Lecithin-cholesterol acyltransferase entry,similarity:Belongs to the AB hydrolase superfamily. Lipase family.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： Secreted . Secreted into blood plasma (PubMed:3458198, PubMed:8820107, PubMed:10222237). Produced in astrocytes and secreted into cerebral spinal fluid (CSF) (PubMed:10222237). .
組織表達(dá)： Detected in blood plasma (PubMed:3458198, PubMed:8820107, PubMed:10222237). Detected in cerebral spinal fluid (at protein level) (PubMed:10222237). Detected in liver (PubMed:3797244, PubMed:3458198). Expressed mainly in brain, liver and testes.
科研貨號： PLA020240

LCAT rabbit pAb

Catalog No PLA020240

Product information

基因名稱： LCAT
蛋白名稱： LCAT
Human_gene_id： 3931
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=3931
Human_swiss_prot_no： P04180
Human_swiss_link： https://www.uniprot.org/uniprotkb/P04180/entry
Mouse_gene_id： 16816
Mouse_gene_link： https://www.uniprot.org/uniprot/16816
Mouse_swiss_prot_no： P16301
Mouse_swiss_link： https://www.uniprot.org/uniprotkb/P16301
Rat_swiss_prot_no： P18424
Rat_swiss_link： https://www.uniprot.org/uniprotkb/P18424
特異性： This antibody detects endogenous levels of LCAT at Human/Mouse/Rat
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來源： Polyclonal, Rabbit,IgG
稀釋： WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度： 1 mg/ml
儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
說明書： 1
Msds： MSDS_Antibody.pdf
分子量： 48kD
功能： catalytic activity:Phosphatidylcholine + a sterol = 1-acylglycerophosphocholine + a sterol ester.,disease:Defects in LCAT are a cause of fish-eye disease (FED) [MIM:136120]; also known as dyslipoproteinemic corneal dystrophy or alpha-LCAT deficiency. FED is due to a partial LCAT deficiency that affects only alpha-LCAT activity. It is characterized by low plasma HDL and corneal opacities due to accumulation of cholesterol deposits in the cornea ('fish-eye').,disease:Defects in LCAT are the cause of lecithin-cholesterol acyltransferase deficiency (LCATD) [MIM:245900]; also called Norum disease. LCATD is a disorder of lipoprotein metabolism characterized by inadequate esterification of plasmatic cholesterol. Two clinical forms are recognized: familial LCAT deficiency and fish-eye disease. Familial LCAT deficiency is associated with a complete absence of alpha and beta LCAT activities and results in esterification anomalies involving both HDL (alpha-LCAT activity) and LDL (beta-LCAT activity). It causes a typical triad of diffuse corneal opacities, target cell hemolytic anemia, and proteinuria with renal failure.,enzyme regulation:Apolipoprotein A-I is a potent activator for this enzyme.,function:Central enzyme in the extracellular metabolism of plasma lipoproteins. Among other substrates it esterifies the free cholesterol transported in plasma lipoproteins.,online information:Lecithin-cholesterol acyltransferase entry,similarity:Belongs to the AB hydrolase superfamily. Lipase family.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： Secreted . Secreted into blood plasma (PubMed:3458198, PubMed:8820107, PubMed:10222237). Produced in astrocytes and secreted into cerebral spinal fluid (CSF) (PubMed:10222237). .
組織表達(dá)： Detected in blood plasma (PubMed:3458198, PubMed:8820107, PubMed:10222237). Detected in cerebral spinal fluid (at protein level) (PubMed:10222237). Detected in liver (PubMed:3797244, PubMed:3458198). Expressed mainly in brain, liver and testes.
科研貨號： PLA020240

Hunan UPT Biotechnology Co.,Ltd

Website：m.tjdqdt.com Servive hotline :4006916686

E-mail：service@uptbio.com

Address：

Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.

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