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S12A3 rabbit pAb

商品貨號(hào)： PLA020183

適應(yīng) 性： 人,小鼠,大鼠

￥600元

規(guī)格：

40μL 100μL 200μL

在線咨詢(xún)

MSDS

說(shuō)明書(shū)

商品描述

基因名稱(chēng)： SLC12A3 TSC
蛋白名稱(chēng)： S12A3
Human_gene_id： 6559
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=6559
Human_swiss_prot_no： P55017
Human_swiss_link： https://www.uniprot.org/uniprotkb/P55017/entry
Mouse_gene_id： 20497
Mouse_gene_link： https://www.uniprot.org/uniprot/20497
Mouse_swiss_prot_no： P59158
Mouse_swiss_link： https://www.uniprot.org/uniprotkb/P59158
Rat_gene_id： 54300
Rat_gene_link： https://www.uniprot.org/uniprot/54300
Rat_swiss_prot_no： P55018
Rat_swiss_link： https://www.uniprot.org/uniprotkb/P55018
特異性： This antibody detects endogenous levels of S12A3 at Human/Mouse/Rat
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來(lái)源： Polyclonal, Rabbit,IgG
稀釋?zhuān)? WB 1：500-2000
純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度： 1 mg/ml
儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
說(shuō)明書(shū)： 1
Msds： MSDS_Antibody.pdf
分子量： 112kD
功能： disease:Defects in SLC12A3 are the cause of Gitelman syndrome (GS) [MIM:263800]. GS is an autosomal recessive disorder characterized by hypokalemic alkalosis in combination with hypomagnesemia, low urinary calcium, and increased renin activity associated with normal blood pressure. Patients are often asymptomatic or present transient periods of muscular weakness and tetany, usually accompanied by abdominal pain, vomiting and fever. The phenotype is highly heterogeneous in terms of age at onset and severity. Cardinal features such as hypocalciuria and hypomagnesemia might also change during the life cycle of a given patient. GS has overlapping features with Bartter syndrome.,function:Electrically silent transporter system. Mediates sodium and chloride reabsorption.,similarity:Belongs to the SLC12A transporter family.,tissue specificity:Predominant in kidney.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： Cell membrane ; Multi-pass membrane protein . Apical cell membrane ; Multi-pass membrane protein .
組織表達(dá)： Predominantly expressed in the kidney (at protein level) (PubMed:29993276, PubMed:8812482). Localizes to the distal convoluted tubules (at protein level)(PubMed:29993276). Not detected in normal aorta, but abundantly expressed in fatty streaks and advanced atherosclerotic lesions (at protein level) (PubMed:26099046).
科研貨號(hào)： PLA020183

S12A3 rabbit pAb

Catalog No PLA020183

Product information

基因名稱(chēng)： SLC12A3 TSC
蛋白名稱(chēng)： S12A3
Human_gene_id： 6559
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=6559
Human_swiss_prot_no： P55017
Human_swiss_link： https://www.uniprot.org/uniprotkb/P55017/entry
Mouse_gene_id： 20497
Mouse_gene_link： https://www.uniprot.org/uniprot/20497
Mouse_swiss_prot_no： P59158
Mouse_swiss_link： https://www.uniprot.org/uniprotkb/P59158
Rat_gene_id： 54300
Rat_gene_link： https://www.uniprot.org/uniprot/54300
Rat_swiss_prot_no： P55018
Rat_swiss_link： https://www.uniprot.org/uniprotkb/P55018
特異性： This antibody detects endogenous levels of S12A3 at Human/Mouse/Rat
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來(lái)源： Polyclonal, Rabbit,IgG
稀釋?zhuān)? WB 1：500-2000
純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度： 1 mg/ml
儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
說(shuō)明書(shū)： 1
Msds： MSDS_Antibody.pdf
分子量： 112kD
功能： disease:Defects in SLC12A3 are the cause of Gitelman syndrome (GS) [MIM:263800]. GS is an autosomal recessive disorder characterized by hypokalemic alkalosis in combination with hypomagnesemia, low urinary calcium, and increased renin activity associated with normal blood pressure. Patients are often asymptomatic or present transient periods of muscular weakness and tetany, usually accompanied by abdominal pain, vomiting and fever. The phenotype is highly heterogeneous in terms of age at onset and severity. Cardinal features such as hypocalciuria and hypomagnesemia might also change during the life cycle of a given patient. GS has overlapping features with Bartter syndrome.,function:Electrically silent transporter system. Mediates sodium and chloride reabsorption.,similarity:Belongs to the SLC12A transporter family.,tissue specificity:Predominant in kidney.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： Cell membrane ; Multi-pass membrane protein . Apical cell membrane ; Multi-pass membrane protein .
組織表達(dá)： Predominantly expressed in the kidney (at protein level) (PubMed:29993276, PubMed:8812482). Localizes to the distal convoluted tubules (at protein level)(PubMed:29993276). Not detected in normal aorta, but abundantly expressed in fatty streaks and advanced atherosclerotic lesions (at protein level) (PubMed:26099046).
科研貨號(hào)： PLA020183

Hunan UPT Biotechnology Co.,Ltd

Website：m.tjdqdt.com Servive hotline :4006916686

E-mail：service@uptbio.com

Address：

Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.

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