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PLCD3 rabbit pAb

商品貨號： PLA020131

適應(yīng) 性： 人,小鼠

￥600元

規(guī)格：

40μL 100μL 200μL

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MSDS

說明書

商品描述

基因名稱： PLCD3 KIAA1964
蛋白名稱： PLCD3
Human_gene_id： 113026
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=113026
Human_swiss_prot_no： Q8N3E9
Human_swiss_link： https://www.uniprot.org/uniprotkb/Q8N3E9/entry
Mouse_gene_id： 72469
Mouse_gene_link： https://www.uniprot.org/uniprot/72469
Mouse_swiss_prot_no： Q8K2J0
Mouse_swiss_link： https://www.uniprot.org/uniprotkb/Q8K2J0
特異性： This antibody detects endogenous levels of PLCD3 at Human/Mouse
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來源： Polyclonal, Rabbit,IgG
稀釋： WB 1:500-2000;IHC-p 1:50-300
純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度： 1 mg/ml
儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
說明書： 1
Msds： MSDS_Antibody.pdf
分子量： 87kD
功能： catalytic activity:1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H(2)O = 1D-myo-inositol 1,4,5-trisphosphate + diacylglycerol.,cofactor:Binds 3 calcium ions per subunit. Two of the calcium ions are bound to the C2 domain.,domain:The C2 domain is a Ca(2+)-dependent membrane-targeting module.,domain:The PH domain mediates interaction with the surface membrane by binding to PIP2.,enzyme regulation:Strongly activated by phosphatidic acid. Inhibited by phosphatidylethanolamine (PtdEtn), phosphatidylcholine (PtdCho), sphingomyelin and phosphatidylserine (PtdSer).,function:Hydrolyzes the phosphatidylinositol 4,5-bisphosphate (PIP2) to generate 2 second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). DAG mediates the activation of protein kinase C (PKC), while IP3 releases Ca(2+) from intracellular stores. Essential for trophoblast and placental development. May participate in cytokinesis by hydrolyzing PIP2 at the cleavage furrow.,induction:Down-regulated by Ca(2+) and cAMP.,similarity:Contains 1 C2 domain.,similarity:Contains 1 PH domain.,similarity:Contains 1 PI-PLC X-box domain.,similarity:Contains 1 PI-PLC Y-box domain.,similarity:Contains 3 EF-hand domains.,subcellular location:Localizes at the cleavage furrow during cytokinesis.,tissue specificity:Present in corneal epithelial cells (at protein level).,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： Membrane; Peripheral membrane protein. Cytoplasm. Cleavage furrow . Localizes at the cleavage furrow during cytokinesis. .
組織表達(dá)： Present in corneal epithelial cells (at protein level).
科研貨號： PLA020131

PLCD3 rabbit pAb

Catalog No PLA020131

Product information

基因名稱： PLCD3 KIAA1964
蛋白名稱： PLCD3
Human_gene_id： 113026
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=113026
Human_swiss_prot_no： Q8N3E9
Human_swiss_link： https://www.uniprot.org/uniprotkb/Q8N3E9/entry
Mouse_gene_id： 72469
Mouse_gene_link： https://www.uniprot.org/uniprot/72469
Mouse_swiss_prot_no： Q8K2J0
Mouse_swiss_link： https://www.uniprot.org/uniprotkb/Q8K2J0
特異性： This antibody detects endogenous levels of PLCD3 at Human/Mouse
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來源： Polyclonal, Rabbit,IgG
稀釋： WB 1:500-2000;IHC-p 1:50-300
純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度： 1 mg/ml
儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
說明書： 1
Msds： MSDS_Antibody.pdf
分子量： 87kD
功能： catalytic activity:1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H(2)O = 1D-myo-inositol 1,4,5-trisphosphate + diacylglycerol.,cofactor:Binds 3 calcium ions per subunit. Two of the calcium ions are bound to the C2 domain.,domain:The C2 domain is a Ca(2+)-dependent membrane-targeting module.,domain:The PH domain mediates interaction with the surface membrane by binding to PIP2.,enzyme regulation:Strongly activated by phosphatidic acid. Inhibited by phosphatidylethanolamine (PtdEtn), phosphatidylcholine (PtdCho), sphingomyelin and phosphatidylserine (PtdSer).,function:Hydrolyzes the phosphatidylinositol 4,5-bisphosphate (PIP2) to generate 2 second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). DAG mediates the activation of protein kinase C (PKC), while IP3 releases Ca(2+) from intracellular stores. Essential for trophoblast and placental development. May participate in cytokinesis by hydrolyzing PIP2 at the cleavage furrow.,induction:Down-regulated by Ca(2+) and cAMP.,similarity:Contains 1 C2 domain.,similarity:Contains 1 PH domain.,similarity:Contains 1 PI-PLC X-box domain.,similarity:Contains 1 PI-PLC Y-box domain.,similarity:Contains 3 EF-hand domains.,subcellular location:Localizes at the cleavage furrow during cytokinesis.,tissue specificity:Present in corneal epithelial cells (at protein level).,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： Membrane; Peripheral membrane protein. Cytoplasm. Cleavage furrow . Localizes at the cleavage furrow during cytokinesis. .
組織表達(dá)： Present in corneal epithelial cells (at protein level).
科研貨號： PLA020131

Hunan UPT Biotechnology Co.,Ltd

Website：m.tjdqdt.com Servive hotline :4006916686

E-mail：service@uptbio.com

Address：

Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.

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