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KMO rabbit pAb

商品貨號(hào)： PLA020125

適應(yīng) 性： 人,小鼠,大鼠

￥600元

規(guī)格：

40μL 100μL 200μL

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MSDS

說明書

商品描述

基因名稱： KMO
蛋白名稱： KMO
Human_gene_id： 8564
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=8564
Human_swiss_prot_no： O15229
Human_swiss_link： https://www.uniprot.org/uniprotkb/O15229/entry
Mouse_gene_id： 98256
Mouse_gene_link： https://www.uniprot.org/uniprot/98256
Mouse_swiss_prot_no： Q91WN4
Mouse_swiss_link： https://www.uniprot.org/uniprotkb/Q91WN4
Rat_gene_id： 59113
Rat_gene_link： https://www.uniprot.org/uniprot/59113
Rat_swiss_prot_no： O88867
Rat_swiss_link： https://www.uniprot.org/uniprotkb/O88867
特異性： This antibody detects endogenous levels of KMO at Human/Mouse/Rat
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來源： Polyclonal, Rabbit,IgG
稀釋： WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度： 1 mg/ml
儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
說明書： 1
Msds： MSDS_Antibody.pdf
分子量： 53kD
功能： catalytic activity:L-kynurenine + NADPH + O(2) = 3-hydroxy-L-kynurenine + NADP(+) + H(2)O.,cofactor:FAD.,function:Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid, a neurotoxic NMDA receptor antagonist and potential endogenous inhibitor of NMDA receptor signaling in axonal targeting, synaptogenesis and apoptosis during brain development. Quinolinic acid may also affect NMDA receptor signaling in pancreatic beta cells, osteoblasts, myocardial cells, and the gastrointestinal tract.,miscellaneous:Increased in neuroinflammatory conditions. Inhibitors are investigated as potential neuroprotective drugs since they lead to an increased level of kynurenic acid, a neuroprotective NMDA receptor agonist.,pathway:Cofactor biosynthesis; NAD(+) biosynthesis; pyridine-2,3-dicarboxylate from L-kynurenine: step 1/3.,similarity:Belongs to the aromatic-ring hydroxylase family. KMO subfamily.,tissue specificity:Highest levels in placenta and liver. Detectable in kidney.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： Mitochondrion outer membrane ; Multi-pass membrane protein .
組織表達(dá)： Highest levels in placenta and liver. Detectable in kidney.
科研貨號(hào)： PLA020125

KMO rabbit pAb

Catalog No PLA020125

Product information

基因名稱： KMO
蛋白名稱： KMO
Human_gene_id： 8564
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=8564
Human_swiss_prot_no： O15229
Human_swiss_link： https://www.uniprot.org/uniprotkb/O15229/entry
Mouse_gene_id： 98256
Mouse_gene_link： https://www.uniprot.org/uniprot/98256
Mouse_swiss_prot_no： Q91WN4
Mouse_swiss_link： https://www.uniprot.org/uniprotkb/Q91WN4
Rat_gene_id： 59113
Rat_gene_link： https://www.uniprot.org/uniprot/59113
Rat_swiss_prot_no： O88867
Rat_swiss_link： https://www.uniprot.org/uniprotkb/O88867
特異性： This antibody detects endogenous levels of KMO at Human/Mouse/Rat
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來源： Polyclonal, Rabbit,IgG
稀釋： WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度： 1 mg/ml
儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
說明書： 1
Msds： MSDS_Antibody.pdf
分子量： 53kD
功能： catalytic activity:L-kynurenine + NADPH + O(2) = 3-hydroxy-L-kynurenine + NADP(+) + H(2)O.,cofactor:FAD.,function:Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid, a neurotoxic NMDA receptor antagonist and potential endogenous inhibitor of NMDA receptor signaling in axonal targeting, synaptogenesis and apoptosis during brain development. Quinolinic acid may also affect NMDA receptor signaling in pancreatic beta cells, osteoblasts, myocardial cells, and the gastrointestinal tract.,miscellaneous:Increased in neuroinflammatory conditions. Inhibitors are investigated as potential neuroprotective drugs since they lead to an increased level of kynurenic acid, a neuroprotective NMDA receptor agonist.,pathway:Cofactor biosynthesis; NAD(+) biosynthesis; pyridine-2,3-dicarboxylate from L-kynurenine: step 1/3.,similarity:Belongs to the aromatic-ring hydroxylase family. KMO subfamily.,tissue specificity:Highest levels in placenta and liver. Detectable in kidney.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： Mitochondrion outer membrane ; Multi-pass membrane protein .
組織表達(dá)： Highest levels in placenta and liver. Detectable in kidney.
科研貨號(hào)： PLA020125

Hunan UPT Biotechnology Co.,Ltd

Website：m.tjdqdt.com Servive hotline :4006916686

E-mail：service@uptbio.com

Address：

Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.

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