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CRY2 rabbit pAb

商品貨號： PLA019982

適應性： 人,小鼠,大鼠

￥600元

規(guī)格：

40μL 100μL 200μL

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MSDS

說明書

商品描述

基因名稱： CRY2 KIAA0658
蛋白名稱： CRY2
Human_gene_id： 1408
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=1408
Human_swiss_prot_no： Q49AN0
Human_swiss_link： https://www.uniprot.org/uniprotkb/Q49AN0/entry
Mouse_gene_id： 12953
Mouse_gene_link： https://www.uniprot.org/uniprot/12953
Mouse_swiss_prot_no： Q9R194
Mouse_swiss_link： https://www.uniprot.org/uniprotkb/Q9R194
Rat_gene_id： 170917
Rat_gene_link： https://www.uniprot.org/uniprot/170917
Rat_swiss_prot_no： Q923I8
Rat_swiss_link： https://www.uniprot.org/uniprotkb/Q923I8
特異性： This antibody detects endogenous levels of CRY2 at Human/Mouse/Rat
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來源： Polyclonal, Rabbit,IgG
稀釋： WB 1：500-2000
純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度： 1 mg/ml
儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
說明書： 1
Msds： MSDS_Antibody.pdf
分子量： 65kD
功能： cofactor:Binds 1 5,10-methenyltetrahydrofolate non-covalently per subunit.,cofactor:Binds 1 FAD per subunit.,function:Blue light-dependent regulator of the circadian feedback loop. Inhibits CLOCK|NPAS2-ARNTL E box-mediated transcription. Acts, in conjunction with CRY2, in maintaining period length and circadian rhythmicity. Has no photolyase activity. Capable of translocating circadian clock core proteins such as PER proteins to the nucleus. May inhibit CLOCK|NPAS2-ARNTL transcriptional activity through stabilizing the unphosphorylated form of ARNTL.,online information:Cryptochrome entry,PTM:Phosphorylation on Ser-266 by MAPK is important for the inhibition of CLOCK-ARNTL-mediated transcriptional activity. Phosphorylation by CSKNE requires interaction with PER1 or PER2.,similarity:Belongs to the DNA photolyase class-1 family.,similarity:Contains 1 DNA photolyase domain.,subcellular location:Translocated to the nucleus through interaction with other Clock proteins such as PER2 or ARNTL.,subunit:Component of the circadian core oscillator, which includes the CRY proteins, CLOCK or NPAS2, ARNTL or ARNTL2, CSNK1D and/or CSNK1E, TIMELESS, and the PER proteins. Interacts directly with PER1 and PER2 C-terminal domains. Interaction with PER2 inhibits its ubiquitination and vice versa. Interacts with NFIL3.,tissue specificity:Expressed in all tissues examined including fetal brain, fibroblasts, heart, brain, placenta, lung, liver, sketal muscle, kidney, pancreas, spleen, thymus, prostate, testis, ovary, small intestine, colon and leukocytes. Highest levels in heart and skeletal muscle.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細胞定位： Cytoplasm . Nucleus . Translocated to the nucleus through interaction with other Clock proteins such as PER2 or ARNTL.
組織表達： Expressed in all tissues examined including fetal brain, fibroblasts, heart, brain, placenta, lung, liver, skeletal muscle, kidney, pancreas, spleen, thymus, prostate, testis, ovary, small intestine, colon and leukocytes. Highest levels in heart and skeletal muscle.
科研貨號： PLA019982

CRY2 rabbit pAb

Catalog No PLA019982

Product information

基因名稱： CRY2 KIAA0658
蛋白名稱： CRY2
Human_gene_id： 1408
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=1408
Human_swiss_prot_no： Q49AN0
Human_swiss_link： https://www.uniprot.org/uniprotkb/Q49AN0/entry
Mouse_gene_id： 12953
Mouse_gene_link： https://www.uniprot.org/uniprot/12953
Mouse_swiss_prot_no： Q9R194
Mouse_swiss_link： https://www.uniprot.org/uniprotkb/Q9R194
Rat_gene_id： 170917
Rat_gene_link： https://www.uniprot.org/uniprot/170917
Rat_swiss_prot_no： Q923I8
Rat_swiss_link： https://www.uniprot.org/uniprotkb/Q923I8
特異性： This antibody detects endogenous levels of CRY2 at Human/Mouse/Rat
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來源： Polyclonal, Rabbit,IgG
稀釋： WB 1：500-2000
純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度： 1 mg/ml
儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
說明書： 1
Msds： MSDS_Antibody.pdf
分子量： 65kD
功能： cofactor:Binds 1 5,10-methenyltetrahydrofolate non-covalently per subunit.,cofactor:Binds 1 FAD per subunit.,function:Blue light-dependent regulator of the circadian feedback loop. Inhibits CLOCK|NPAS2-ARNTL E box-mediated transcription. Acts, in conjunction with CRY2, in maintaining period length and circadian rhythmicity. Has no photolyase activity. Capable of translocating circadian clock core proteins such as PER proteins to the nucleus. May inhibit CLOCK|NPAS2-ARNTL transcriptional activity through stabilizing the unphosphorylated form of ARNTL.,online information:Cryptochrome entry,PTM:Phosphorylation on Ser-266 by MAPK is important for the inhibition of CLOCK-ARNTL-mediated transcriptional activity. Phosphorylation by CSKNE requires interaction with PER1 or PER2.,similarity:Belongs to the DNA photolyase class-1 family.,similarity:Contains 1 DNA photolyase domain.,subcellular location:Translocated to the nucleus through interaction with other Clock proteins such as PER2 or ARNTL.,subunit:Component of the circadian core oscillator, which includes the CRY proteins, CLOCK or NPAS2, ARNTL or ARNTL2, CSNK1D and/or CSNK1E, TIMELESS, and the PER proteins. Interacts directly with PER1 and PER2 C-terminal domains. Interaction with PER2 inhibits its ubiquitination and vice versa. Interacts with NFIL3.,tissue specificity:Expressed in all tissues examined including fetal brain, fibroblasts, heart, brain, placenta, lung, liver, sketal muscle, kidney, pancreas, spleen, thymus, prostate, testis, ovary, small intestine, colon and leukocytes. Highest levels in heart and skeletal muscle.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細胞定位： Cytoplasm . Nucleus . Translocated to the nucleus through interaction with other Clock proteins such as PER2 or ARNTL.
組織表達： Expressed in all tissues examined including fetal brain, fibroblasts, heart, brain, placenta, lung, liver, skeletal muscle, kidney, pancreas, spleen, thymus, prostate, testis, ovary, small intestine, colon and leukocytes. Highest levels in heart and skeletal muscle.
科研貨號： PLA019982

Hunan UPT Biotechnology Co.,Ltd

Website：m.tjdqdt.com Servive hotline :4006916686

E-mail：service@uptbio.com

Address：

Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.

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