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CLIC5 rabbit pAb

商品貨號： PLA019977

適應性： 人,小鼠,大鼠

￥600元

規(guī)格：

40μL 100μL 200μL

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MSDS

說明書

商品描述

基因名稱： CLIC5
蛋白名稱： CLIC5
Human_gene_id： 53405
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=53405
Human_swiss_prot_no： Q9NZA1
Human_swiss_link： https://www.uniprot.org/uniprotkb/Q9NZA1/entry
Mouse_gene_id： 224796
Mouse_gene_link： https://www.uniprot.org/uniprot/224796
Mouse_swiss_prot_no： Q8BXK9
Mouse_swiss_link： https://www.uniprot.org/uniprotkb/Q8BXK9
Rat_gene_id： 94272
Rat_gene_link： https://www.uniprot.org/uniprot/94272
Rat_swiss_prot_no： Q9EPT8
Rat_swiss_link： https://www.uniprot.org/uniprotkb/Q9EPT8
特異性： This antibody detects endogenous levels of CLIC5 at Human/Mouse/Rat
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來源： Polyclonal, Rabbit,IgG
稀釋： WB 1：500-2000
純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度： 1 mg/ml
儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
說明書： 1
Msds： MSDS_Antibody.pdf
分子量： 45kD
功能： domain:Members of this family may change from a globular, soluble state to a state where the N-terminal domain is inserted into the membrane and functions as chloride channel. A conformation change of the N-terminal domain is thought to expose hydrophobic surfaces that trigger membrane insertion.,function:Can insert into membranes and form poorly selective ion channels that may also transport chloride ions. May play a role in the regulation of transepithelial ion absorption and secretion. Required for normal formation of stereocilia in the inner ear and normal development of the organ of Corti.,similarity:Belongs to the chloride channel CLIC family.,similarity:Contains 1 GST C-terminal domain.,subcellular location:Associates with the cortical actin cytoskeleton. Exists both as soluble cytoplasmic protein and as membrane protein with probably a single transmembrane domain.,subcellular location:Colocalized with AKAP9 at the Golgi apparatus as well as, to a lesser extent, the centrosome. Exists both as soluble cytoplasmic protein and as membrane protein with probably a single transmembrane domain.,subunit:Component of a multimeric complex consisting of several cytoskeletal proteins, including actin, ezrin, alpha-actinin, gelsolin, and IQGAP1.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細胞定位： [Isoform 1]: Cytoplasm, cytoskeleton . Cytoplasm, cell cortex . Membrane ; Single-pass membrane protein . Apical cell membrane ; Single-pass membrane protein . Cytoplasm . Associates with the cortical actin cytoskeleton (PubMed:10793131, PubMed:15184393). Localizes to the apical region of cochlear hair cells, at the base of the actin-rich hair bundle (By similarity). Colocalizes with podocalyxin at the apical cell membrane in renal glomeruli (PubMed:20335315). May localize to the centrosome in lens epithelial cells (By similarity). Exists both as soluble cytoplasmic protein and as membrane protein with probably a single transmembrane domain (By similarity). .; [Isoform 2]: Golgi apparatus . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Colocalizes with AKAP9 at the Golgi apparatus as well as, to a lesser extent, the centrosome. .
組織表達： Widely expressed in both fetal and adult human tissues (PubMed:24781754). Isoform 1 is expressed in renal glomeruli endothelial cells and podocytes (at protein level).
科研貨號： PLA019977

CLIC5 rabbit pAb

Catalog No PLA019977

Product information

基因名稱： CLIC5
蛋白名稱： CLIC5
Human_gene_id： 53405
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=53405
Human_swiss_prot_no： Q9NZA1
Human_swiss_link： https://www.uniprot.org/uniprotkb/Q9NZA1/entry
Mouse_gene_id： 224796
Mouse_gene_link： https://www.uniprot.org/uniprot/224796
Mouse_swiss_prot_no： Q8BXK9
Mouse_swiss_link： https://www.uniprot.org/uniprotkb/Q8BXK9
Rat_gene_id： 94272
Rat_gene_link： https://www.uniprot.org/uniprot/94272
Rat_swiss_prot_no： Q9EPT8
Rat_swiss_link： https://www.uniprot.org/uniprotkb/Q9EPT8
特異性： This antibody detects endogenous levels of CLIC5 at Human/Mouse/Rat
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來源： Polyclonal, Rabbit,IgG
稀釋： WB 1：500-2000
純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度： 1 mg/ml
儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
說明書： 1
Msds： MSDS_Antibody.pdf
分子量： 45kD
功能： domain:Members of this family may change from a globular, soluble state to a state where the N-terminal domain is inserted into the membrane and functions as chloride channel. A conformation change of the N-terminal domain is thought to expose hydrophobic surfaces that trigger membrane insertion.,function:Can insert into membranes and form poorly selective ion channels that may also transport chloride ions. May play a role in the regulation of transepithelial ion absorption and secretion. Required for normal formation of stereocilia in the inner ear and normal development of the organ of Corti.,similarity:Belongs to the chloride channel CLIC family.,similarity:Contains 1 GST C-terminal domain.,subcellular location:Associates with the cortical actin cytoskeleton. Exists both as soluble cytoplasmic protein and as membrane protein with probably a single transmembrane domain.,subcellular location:Colocalized with AKAP9 at the Golgi apparatus as well as, to a lesser extent, the centrosome. Exists both as soluble cytoplasmic protein and as membrane protein with probably a single transmembrane domain.,subunit:Component of a multimeric complex consisting of several cytoskeletal proteins, including actin, ezrin, alpha-actinin, gelsolin, and IQGAP1.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細胞定位： [Isoform 1]: Cytoplasm, cytoskeleton . Cytoplasm, cell cortex . Membrane ; Single-pass membrane protein . Apical cell membrane ; Single-pass membrane protein . Cytoplasm . Associates with the cortical actin cytoskeleton (PubMed:10793131, PubMed:15184393). Localizes to the apical region of cochlear hair cells, at the base of the actin-rich hair bundle (By similarity). Colocalizes with podocalyxin at the apical cell membrane in renal glomeruli (PubMed:20335315). May localize to the centrosome in lens epithelial cells (By similarity). Exists both as soluble cytoplasmic protein and as membrane protein with probably a single transmembrane domain (By similarity). .; [Isoform 2]: Golgi apparatus . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Colocalizes with AKAP9 at the Golgi apparatus as well as, to a lesser extent, the centrosome. .
組織表達： Widely expressed in both fetal and adult human tissues (PubMed:24781754). Isoform 1 is expressed in renal glomeruli endothelial cells and podocytes (at protein level).
科研貨號： PLA019977

Hunan UPT Biotechnology Co.,Ltd

Website：m.tjdqdt.com Servive hotline :4006916686

E-mail：service@uptbio.com

Address：

Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.

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