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DDX1 rabbit pAb

商品貨號： PLA019947

適應(yīng) 性： 人,小鼠,大鼠

￥600元

規(guī)格：

40μL 100μL 200μL

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MSDS

說明書

商品描述

基因名稱： DDX1
蛋白名稱： DDX1
Human_gene_id： 1653
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=1653
Human_swiss_prot_no： Q92499
Human_swiss_link： https://www.uniprot.org/uniprotkb/Q92499/entry
Mouse_gene_id： 104721
Mouse_gene_link： https://www.uniprot.org/uniprot/104721
Mouse_swiss_prot_no： Q91VR5
Mouse_swiss_link： https://www.uniprot.org/uniprotkb/Q91VR5
Rat_gene_id： 84474
Rat_gene_link： https://www.uniprot.org/uniprot/84474
Rat_swiss_prot_no： Q641Y8
Rat_swiss_link： https://www.uniprot.org/uniprotkb/Q641Y8
特異性： This antibody detects endogenous levels of DDX1 at Human/Mouse/Rat
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來源： Polyclonal, Rabbit,IgG
稀釋： WB 1：500-2000
純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度： 1 mg/ml
儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
說明書： 1
Msds： MSDS_Antibody.pdf
分子量： 81kD
功能： similarity:Belongs to the DEAD box helicase family. DDX1 subfamily.,similarity:Contains 1 B30.2/SPRY domain.,similarity:Contains 1 helicase ATP-binding domain.,similarity:Contains 1 helicase C-terminal domain.,tissue specificity:Highest levels of transcription in 2 retinoblastoma cell lines and in tissues of neuroectodermal origin including the retina, brain, and spinal cord.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： Nucleus. Cytoplasm. Cytoplasmic granule. Cytoplasm, cytosol . Mitochondrion . Localized with MBNL1, TIAL1 and YBX1 in stress granules upon stress. Localized with CSTF2 in cleavage bodies. Forms large aggregates called DDX1 bodies. Relocalized into multiple foci (IR-induced foci or IRIF) after IR treatment, a process that depends on the presence of chromosomal DNA and/or RNA-DNA duplexes. Relocalized at sites of DNA double-strand breaks (DSBs) in an ATM-dependent manner after IR treatment. Colocalized with RELA in the nucleus upon TNF-alpha induction. Enters into the nucleus in case of active transcription while it accumulates in cytosol when transcription level is low (PubMed:24608264). Colocalizes in the cytosol with DDX21, DHX36 and TICAM1. Colocalizes in the mitochondria with TICAM1 and poly(I:C) RNA ligand. The multi-helicase-TICAM1 complex may translocate to the mitochondria upon poly(I:C) stimulation (By similarity). .; Cytoplasm . (Microbial infection) Relocalized to the cytoplasm with a perinuclear staining pattern in avian infectious bronchitis virus (IBV)-infected cells (PubMed:20573827). Required for proper localization of HIV-1 Rev (PubMed:15567440). .
組織表達(dá)： Highest levels of transcription in 2 retinoblastoma cell lines and in tissues of neuroectodermal origin including the retina, brain, and spinal cord.
科研貨號： PLA019947

DDX1 rabbit pAb

Catalog No PLA019947

Product information

基因名稱： DDX1
蛋白名稱： DDX1
Human_gene_id： 1653
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=1653
Human_swiss_prot_no： Q92499
Human_swiss_link： https://www.uniprot.org/uniprotkb/Q92499/entry
Mouse_gene_id： 104721
Mouse_gene_link： https://www.uniprot.org/uniprot/104721
Mouse_swiss_prot_no： Q91VR5
Mouse_swiss_link： https://www.uniprot.org/uniprotkb/Q91VR5
Rat_gene_id： 84474
Rat_gene_link： https://www.uniprot.org/uniprot/84474
Rat_swiss_prot_no： Q641Y8
Rat_swiss_link： https://www.uniprot.org/uniprotkb/Q641Y8
特異性： This antibody detects endogenous levels of DDX1 at Human/Mouse/Rat
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來源： Polyclonal, Rabbit,IgG
稀釋： WB 1：500-2000
純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度： 1 mg/ml
儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
說明書： 1
Msds： MSDS_Antibody.pdf
分子量： 81kD
功能： similarity:Belongs to the DEAD box helicase family. DDX1 subfamily.,similarity:Contains 1 B30.2/SPRY domain.,similarity:Contains 1 helicase ATP-binding domain.,similarity:Contains 1 helicase C-terminal domain.,tissue specificity:Highest levels of transcription in 2 retinoblastoma cell lines and in tissues of neuroectodermal origin including the retina, brain, and spinal cord.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： Nucleus. Cytoplasm. Cytoplasmic granule. Cytoplasm, cytosol . Mitochondrion . Localized with MBNL1, TIAL1 and YBX1 in stress granules upon stress. Localized with CSTF2 in cleavage bodies. Forms large aggregates called DDX1 bodies. Relocalized into multiple foci (IR-induced foci or IRIF) after IR treatment, a process that depends on the presence of chromosomal DNA and/or RNA-DNA duplexes. Relocalized at sites of DNA double-strand breaks (DSBs) in an ATM-dependent manner after IR treatment. Colocalized with RELA in the nucleus upon TNF-alpha induction. Enters into the nucleus in case of active transcription while it accumulates in cytosol when transcription level is low (PubMed:24608264). Colocalizes in the cytosol with DDX21, DHX36 and TICAM1. Colocalizes in the mitochondria with TICAM1 and poly(I:C) RNA ligand. The multi-helicase-TICAM1 complex may translocate to the mitochondria upon poly(I:C) stimulation (By similarity). .; Cytoplasm . (Microbial infection) Relocalized to the cytoplasm with a perinuclear staining pattern in avian infectious bronchitis virus (IBV)-infected cells (PubMed:20573827). Required for proper localization of HIV-1 Rev (PubMed:15567440). .
組織表達(dá)： Highest levels of transcription in 2 retinoblastoma cell lines and in tissues of neuroectodermal origin including the retina, brain, and spinal cord.
科研貨號： PLA019947

Hunan UPT Biotechnology Co.,Ltd

Website：m.tjdqdt.com Servive hotline :4006916686

E-mail：service@uptbio.com

Address：

Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.

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