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C8AP2 rabbit pAb

商品貨號： PLA019923

適應(yīng) 性： 人,小鼠

￥600元

規(guī)格：

40μL 100μL 200μL

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MSDS

說明書

商品描述

基因名稱： CASP8AP2 FLASH KIAA1315 RIP25
蛋白名稱： C8AP2
Human_gene_id： 9994
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=9994
Human_swiss_prot_no： Q9UKL3
Human_swiss_link： https://www.uniprot.org/uniprotkb/Q9UKL3/entry
Mouse_gene_id： 26885
Mouse_gene_link： https://www.uniprot.org/uniprot/26885
Mouse_swiss_prot_no： Q9WUF3
Mouse_swiss_link： https://www.uniprot.org/uniprotkb/Q9WUF3
特異性： This antibody detects endogenous levels of C8AP2 at Human/Mouse
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來源： Polyclonal, Rabbit,IgG
稀釋： WB 1：500-2000
純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度： 1 mg/ml
儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
說明書： 1
Msds： MSDS_Antibody.pdf
分子量： 218kD
功能： function:Participates in TNF-alpha-induced blockade of glucocorticoid receptor (GR) transactivation at the nuclear receptor coactivator level, upstream and independently of NF-kappa-B. Suppresses both NCOA2- and NCOA3-induced enhancement of GR transactivation. Involved in TNF-alpha-induced activation of NF-kappa-B via a TRAF2-dependent pathway. Acts as a downstream mediator for CASP8-induced activation of NF-kappa-B. Required for the activation of CASP8 in FAS-mediated apoptosis. Required for histone gene transcription and progression through S phase.,induction:By TNF-alpha, which induces strong nuclear localization.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,sequence caution:Contaminating sequence. Potential poly-A sequence starting in position 364.,subcellular location:Localizes to discrete nuclear foci.,subunit:Self-associates. Component of the death-inducing signaling complex (DISC) with CASP8, FADD and FAS. Interacts with NCOA2, NCOA3 and TRAF2. Interacts with NPAT.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： Cytoplasm. Nucleus. Nucleus, PML body. Mitochondrion. Exported from the nucleus to the mitochondria upon FAS activation.
科研貨號： PLA019923

C8AP2 rabbit pAb

Catalog No PLA019923

Product information

基因名稱： CASP8AP2 FLASH KIAA1315 RIP25
蛋白名稱： C8AP2
Human_gene_id： 9994
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=9994
Human_swiss_prot_no： Q9UKL3
Human_swiss_link： https://www.uniprot.org/uniprotkb/Q9UKL3/entry
Mouse_gene_id： 26885
Mouse_gene_link： https://www.uniprot.org/uniprot/26885
Mouse_swiss_prot_no： Q9WUF3
Mouse_swiss_link： https://www.uniprot.org/uniprotkb/Q9WUF3
特異性： This antibody detects endogenous levels of C8AP2 at Human/Mouse
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來源： Polyclonal, Rabbit,IgG
稀釋： WB 1：500-2000
純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度： 1 mg/ml
儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
說明書： 1
Msds： MSDS_Antibody.pdf
分子量： 218kD
功能： function:Participates in TNF-alpha-induced blockade of glucocorticoid receptor (GR) transactivation at the nuclear receptor coactivator level, upstream and independently of NF-kappa-B. Suppresses both NCOA2- and NCOA3-induced enhancement of GR transactivation. Involved in TNF-alpha-induced activation of NF-kappa-B via a TRAF2-dependent pathway. Acts as a downstream mediator for CASP8-induced activation of NF-kappa-B. Required for the activation of CASP8 in FAS-mediated apoptosis. Required for histone gene transcription and progression through S phase.,induction:By TNF-alpha, which induces strong nuclear localization.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,sequence caution:Contaminating sequence. Potential poly-A sequence starting in position 364.,subcellular location:Localizes to discrete nuclear foci.,subunit:Self-associates. Component of the death-inducing signaling complex (DISC) with CASP8, FADD and FAS. Interacts with NCOA2, NCOA3 and TRAF2. Interacts with NPAT.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： Cytoplasm. Nucleus. Nucleus, PML body. Mitochondrion. Exported from the nucleus to the mitochondria upon FAS activation.
科研貨號： PLA019923

Hunan UPT Biotechnology Co.,Ltd

Website：m.tjdqdt.com Servive hotline :4006916686

E-mail：service@uptbio.com

Address：

Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.

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