功能： catalytic activity:GDP-beta-L-fucose + beta-D-galactosyl-(1->3)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide = GDP + alpha-L-fucosyl-(1->2)-beta-D-galactosyl-(1->3)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide.,function:Creates a soluble precursor oligosaccharide FuC-alpha ((1,2)Galbeta-) called the H antigen which is an essential substrate for the final step in the soluble A and B antigen synthesis pathway. H and Se enzymes fucosylate the same acceptor substrates but exhibit different Km values.,miscellaneous:There are two genes (FUT1 and FUT2) which encode galactoside 2-L-fucosyltransferase. They are expressed in a tissue-specific manner with expression restricted to cells of mesodermal or endodermal origin respectively.,online information:Blood group antigen gene mutation database,online information:Fucosyltransferase 1,online information:GlycoGene database,pathway:Protein modification; protein glycosylation.,polymorphism:Nonfunctional mutant of FUT1 are the cause of the H-Bombay blood group.,similarity:Belongs to the glycosyltransferase 11 family.,subcellular location:Membrane-bound form in trans cisternae of Golgi.,
相關產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細胞定位： Golgi apparatus, Golgi stack membrane ; Single-pass type II membrane protein . Membrane-bound form in trans cisternae of Golgi. .
功能： catalytic activity:GDP-beta-L-fucose + beta-D-galactosyl-(1->3)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide = GDP + alpha-L-fucosyl-(1->2)-beta-D-galactosyl-(1->3)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide.,function:Creates a soluble precursor oligosaccharide FuC-alpha ((1,2)Galbeta-) called the H antigen which is an essential substrate for the final step in the soluble A and B antigen synthesis pathway. H and Se enzymes fucosylate the same acceptor substrates but exhibit different Km values.,miscellaneous:There are two genes (FUT1 and FUT2) which encode galactoside 2-L-fucosyltransferase. They are expressed in a tissue-specific manner with expression restricted to cells of mesodermal or endodermal origin respectively.,online information:Blood group antigen gene mutation database,online information:Fucosyltransferase 1,online information:GlycoGene database,pathway:Protein modification; protein glycosylation.,polymorphism:Nonfunctional mutant of FUT1 are the cause of the H-Bombay blood group.,similarity:Belongs to the glycosyltransferase 11 family.,subcellular location:Membrane-bound form in trans cisternae of Golgi.,
相關產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細胞定位： Golgi apparatus, Golgi stack membrane ; Single-pass type II membrane protein . Membrane-bound form in trans cisternae of Golgi. .
科研貨號： PLA019860
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