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Histone H2A.Z Polyclonal Antibody

商品貨號： PLA019432

適應性： 人,小鼠,大鼠

￥600元

規(guī)格：

40μL 100μL 200μL

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MSDS

說明書

商品描述

基因名稱： H2AFZ H2AZ
蛋白名稱： Histone H2A.Z (H2A/z)
Human_gene_id： 3015
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=3015
Human_swiss_prot_no： P0C0S5
Human_swiss_link： http://www.uniprot.org/uniprotkb/P0C0S5/entry
Mouse_gene_id： 51788
Mouse_swiss_prot_no： P0C0S6
Mouse_swiss_link： http://www.uniprot.org/uniprot/P0C0S6
Rat_swiss_prot_no： P0C0S7
Rat_swiss_link： http://www.uniprot.org/uniprot/O54941P0C0S7
特異性： The antibody detects endogenous Histone H2A.Z
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來源： Polyclonal, Rabbit,IgG
稀釋： WB 1:500-2000, ELISA 1:10000-20000
純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度： 1 mg/ml
儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
說明書： 1
Msds： MSDS_Antibody.pdf
其他名稱： Histone H2A.Z (H2A/z)
實測條帶： 20kD
信號通路： Systemic lupus erythematosus;
功能： function:Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in the formation of constitutive heterochromatin. May be required for chromosome segregation during cell division.,mass spectrometry:Monoisotopic, not modified PubMed:16457589,PTM:Acetylated on Lys-5, Lys-8 and Lys-12 during interphase. Acetylation disappears at mitosis.,PTM:Monoubiquitination of Lys-122 gives a specific tag for epigenetic transcriptional repression.,PTM:Not phosphorylated.,similarity:Belongs to the histone H2A family.,subunit:The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. H2A or its variant H2AFZ forms an heterodimer with H2B. H2AFZ interacts with INCENP.,
相關產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細胞定位： Nucleus. Chromosome.
組織表達： Brain,Epithelium,Skeletal muscle,Uterus,
科研貨號： PLA019432

Histone H2A.Z Polyclonal Antibody

Catalog No PLA019432

Product information

基因名稱： H2AFZ H2AZ
蛋白名稱： Histone H2A.Z (H2A/z)
Human_gene_id： 3015
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=3015
Human_swiss_prot_no： P0C0S5
Human_swiss_link： http://www.uniprot.org/uniprotkb/P0C0S5/entry
Mouse_gene_id： 51788
Mouse_swiss_prot_no： P0C0S6
Mouse_swiss_link： http://www.uniprot.org/uniprot/P0C0S6
Rat_swiss_prot_no： P0C0S7
Rat_swiss_link： http://www.uniprot.org/uniprot/O54941P0C0S7
特異性： The antibody detects endogenous Histone H2A.Z
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來源： Polyclonal, Rabbit,IgG
稀釋： WB 1:500-2000, ELISA 1:10000-20000
純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度： 1 mg/ml
儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
說明書： 1
Msds： MSDS_Antibody.pdf
其他名稱： Histone H2A.Z (H2A/z)
實測條帶： 20kD
信號通路： Systemic lupus erythematosus;
功能： function:Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in the formation of constitutive heterochromatin. May be required for chromosome segregation during cell division.,mass spectrometry:Monoisotopic, not modified PubMed:16457589,PTM:Acetylated on Lys-5, Lys-8 and Lys-12 during interphase. Acetylation disappears at mitosis.,PTM:Monoubiquitination of Lys-122 gives a specific tag for epigenetic transcriptional repression.,PTM:Not phosphorylated.,similarity:Belongs to the histone H2A family.,subunit:The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. H2A or its variant H2AFZ forms an heterodimer with H2B. H2AFZ interacts with INCENP.,
相關產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細胞定位： Nucleus. Chromosome.
組織表達： Brain,Epithelium,Skeletal muscle,Uterus,
科研貨號： PLA019432

Hunan UPT Biotechnology Co.,Ltd

Website：m.tjdqdt.com Servive hotline :4006916686

E-mail：service@uptbio.com

Address：

Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.

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